trimethoprim has been researched along with Fetal Death in 3 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this dose range the pup weights and the weight gain of the offspring of dams with continued dosing during lactation were also reduced." | 1.26 | [Investigations on the effect of the combination sulfamoxole/trimethoprim on fertility and fetal development in rats and rabbits (author's tranls)]. ( Helm, F; Kretzschmar, R; Leuschner, F; Neumann, W, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haliniarz, W | 2 |
| Sikorski, R | 2 |
| Helm, F | 1 |
| Kretzschmar, R | 1 |
| Leuschner, F | 1 |
| Neumann, W | 1 |
3 other studies available for trimethoprim and Fetal Death
| Article | Year |
|---|---|
[Evaluation of embryotoxicity of Biseptol-Polfa in pregnant female rats and rabbits].
Topics: Animals; Drug Combinations; Drug Evaluation, Preclinical; Ecchymosis; Edema; Embryo, Mammalian; Fema | 1980 |
[Studies on the embryotoxicity of the preparation Biseptol-Polfa in pregnant hamsters].
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Drug Combinations; Drug Evaluation, Preclinical; E | 1979 |
[Investigations on the effect of the combination sulfamoxole/trimethoprim on fertility and fetal development in rats and rabbits (author's tranls)].
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Birth Weight; Drug Combinations; Female; Fer | 1976 |