trimethoprim has been researched along with Exanthema in 18 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Exanthema: Diseases in which skin eruptions or rashes are a prominent manifestation. Classically, six such diseases were described with similar rashes; they were numbered in the order in which they were reported. Only the fourth (Duke's disease), fifth (ERYTHEMA INFECTIOSUM), and sixth (EXANTHEMA SUBITUM) numeric designations survive as occasional synonyms in current terminology.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the pharmacokinetics and safety profile of oral ganciclovir coadministered with trimethoprim in HIV-and CMV-seropositive patients." | 9.09 | The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients. ( AbdelHameed, MH; Dorr, A; Griffy, K; Hunter, J; Jung, D; Teitelbaum, P, 1999) |
| "These results suggest a drug exanthema, in all probability triggered by the leech therapy." | 5.33 | [Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy]. ( Beer, AM; Ciborovius, J; Fey, S; Knorr, M, 2005) |
| "The observed risks of developing an exanthema are as follows: aminopenicillin without allopurinol 10." | 5.27 | [Exanthema during frequent use of antibiotics and antibacterial drugs (penicillin, especially aminopenicillin, cephalosporin and cotrimoxazole) as well as allopurinol. Results of The Berne Comprehensive Hospital Drug Monitoring Program]. ( Buchli, W; Fritschy, D; Hess, T; Hoigné, R; Maibach, R; Sollberger, J; Sonntag, MR; Stocker, F; Zoppi, M, 1986) |
| "We investigated the pharmacokinetics and safety profile of oral ganciclovir coadministered with trimethoprim in HIV-and CMV-seropositive patients." | 5.09 | The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients. ( AbdelHameed, MH; Dorr, A; Griffy, K; Hunter, J; Jung, D; Teitelbaum, P, 1999) |
| "Trimethoprim (TMP)-induced skin rash and liver injury are likely to involve the formation of reactive metabolites." | 1.62 | Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury. ( Bairam, A; Cao, Y; Jee, A; Liu, M; Uetrecht, J, 2021) |
| "Brucellosis is considered a known widespread zoonotic disease and is endemic in Mediterranean region, like Iran." | 1.39 | Clinical manifestations, laboratory findings, and therapeutic regimen in hospitalized children with brucellosis in an Iranian Referral Children Medical Centre. ( Fanni, F; Mahmoudi, S; Mamishi, S; Pourakbari, B; Shahbaznejad, L, 2013) |
| "These results suggest a drug exanthema, in all probability triggered by the leech therapy." | 1.33 | [Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy]. ( Beer, AM; Ciborovius, J; Fey, S; Knorr, M, 2005) |
| "We studied an acute generalized exanthematous pustulosis (AGEP) due to sulfamethoxazol in a 48-year-old woman with unusual findings in allergy testing." | 1.32 | Acute generalized exanthematous pustulosis due to sulfamethoxazol with positive lymphocyte transformation test (LTT). ( Anliker, MD; Wüthrich, B, 2003) |
| "The observed risks of developing an exanthema are as follows: aminopenicillin without allopurinol 10." | 1.27 | [Exanthema during frequent use of antibiotics and antibacterial drugs (penicillin, especially aminopenicillin, cephalosporin and cotrimoxazole) as well as allopurinol. Results of The Berne Comprehensive Hospital Drug Monitoring Program]. ( Buchli, W; Fritschy, D; Hess, T; Hoigné, R; Maibach, R; Sollberger, J; Sonntag, MR; Stocker, F; Zoppi, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Connolly, A | 1 |
| Walsh, S | 1 |
| Philippidou, M | 1 |
| Salisbury, J | 1 |
| Creamer, D | 1 |
| Cao, Y | 1 |
| Bairam, A | 1 |
| Jee, A | 1 |
| Liu, M | 1 |
| Uetrecht, J | 1 |
| Piper, KJ | 1 |
| Foster, H | 1 |
| Susanto, D | 1 |
| Maree, CL | 1 |
| Thornton, SD | 1 |
| Cobbs, CS | 1 |
| Fanni, F | 1 |
| Shahbaznejad, L | 1 |
| Pourakbari, B | 1 |
| Mahmoudi, S | 1 |
| Mamishi, S | 1 |
| Boyd, A | 1 |
| Mills, D | 1 |
| Hook, K | 1 |
| Kaila, R | 1 |
| Iaccheri, B | 1 |
| Fiore, T | 1 |
| Papadaki, T | 1 |
| Androudi, S | 1 |
| Janjua, S | 1 |
| Bhaila, I | 1 |
| Stephen Foster, C | 1 |
| El-Ghaiesh, S | 1 |
| Sanderson, JP | 1 |
| Farrell, J | 1 |
| Lavergne, SN | 1 |
| Syn, WK | 1 |
| Pirmohamed, M | 1 |
| Park, BK | 1 |
| Naisbitt, DJ | 1 |
| Anliker, MD | 1 |
| Wüthrich, B | 1 |
| Beer, AM | 1 |
| Fey, S | 1 |
| Ciborovius, J | 1 |
| Knorr, M | 1 |
| Christensen, G | 1 |
| Jans, H | 1 |
| Larsen, S | 1 |
| Jung, D | 1 |
| AbdelHameed, MH | 1 |
| Hunter, J | 1 |
| Teitelbaum, P | 1 |
| Dorr, A | 1 |
| Griffy, K | 1 |
| Hauser, GA | 1 |
| Jans, J | 1 |
| Sonntag, MR | 1 |
| Zoppi, M | 1 |
| Fritschy, D | 1 |
| Maibach, R | 1 |
| Stocker, F | 1 |
| Sollberger, J | 1 |
| Buchli, W | 1 |
| Hess, T | 1 |
| Hoigné, R | 1 |
| Kerstan, J | 1 |
| Wolf, H | 1 |
| Schulz, KH | 1 |
| Wahnbeck, D | 1 |
| Hohenauer, L | 1 |
| Lalla, M | 1 |
| Virolainen, M | 1 |
| Melén, B | 1 |
| Orsten, PA | 1 |
1 trial available for trimethoprim and Exanthema
| Article | Year |
|---|---|
The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Cross-Over Studies; Cytomegalo | 1999 |
17 other studies available for trimethoprim and Exanthema
| Article | Year |
|---|---|
Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS).
Topics: Drug Eruptions; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Liver Failure, Acut | 2023 |
Investigating the Mechanism of Trimethoprim-Induced Skin Rash and Liver Injury.
Topics: Animals; Exanthema; Humans; Liver; Mice; Nevirapine; Rats; Skin; Trimethoprim | 2021 |
Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage.
Topics: Aged; Balamuthia mandrillaris; Brain; Brain Diseases; Exanthema; Fatal Outcome; Female; Humans; Nasa | 2018 |
Clinical manifestations, laboratory findings, and therapeutic regimen in hospitalized children with brucellosis in an Iranian Referral Children Medical Centre.
Topics: Adolescent; Anti-Infective Agents; Arthritis; Brucellosis; Child; Child, Hospitalized; Child, Presch | 2013 |
Seventeen-year-old sexually active male with rash.
Topics: Acne Vulgaris; Adolescent; Anti-Infective Agents; Drug Hypersensitivity Syndrome; Exanthema; Fever; | 2016 |
Adverse drug reactions to treatments for ocular toxoplasmosis: a retrospective chart review.
Topics: Adolescent; Adult; Atovaquone; Clindamycin; Drug Combinations; Drug-Related Side Effects and Adverse | 2008 |
Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Huma | 2011 |
Acute generalized exanthematous pustulosis due to sulfamethoxazol with positive lymphocyte transformation test (LTT).
Topics: Administration, Topical; Anti-Infective Agents; Anti-Inflammatory Agents; Betamethasone; Drug Erupti | 2003 |
[Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy].
Topics: Anti-Infective Agents; Drug Eruptions; Exanthema; Female; Humans; Leeching; Lymphocyte Activation; M | 2005 |
[Multiple organ involvement following treatment with sulphamethoxazole-trimethoprim (Bactrim)].
Topics: Anti-Infective Agents, Urinary; Arteritis; Drug Combinations; Exanthema; Female; Humans; Liver Funct | 1982 |
[The effect of Bactrim and Tandearil on abnormal tubal patency in cases of infertility (author's transl)].
Topics: Drug Combinations; Endometriosis; Exanthema; Fallopian Tube Patency Tests; Female; Humans; Infertili | 1975 |
[Exanthema during frequent use of antibiotics and antibacterial drugs (penicillin, especially aminopenicillin, cephalosporin and cotrimoxazole) as well as allopurinol. Results of The Berne Comprehensive Hospital Drug Monitoring Program].
Topics: Allopurinol; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Cephalosporins; Dose-Response Relations | 1986 |
[Therapeutic experience with trimethoprim and sulfamethoxazole in infections of infancy and childhood].
Topics: Adolescent; Anti-Infective Agents; Bacterial Infections; Bronchitis; Child; Child, Preschool; Drug S | 1972 |
[Lymphocyte transformation test in drug hypersensitivity].
Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; | 1972 |
[Clinical experiences with the combination of trimethoprim and sulfamethoxazol (Bactrim) in pediatric patients].
Topics: Anti-Infective Agents; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Exanthema; | 1972 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |
[Results of trimethoprim and sulfamethoxazole therapy in chronic urinary tract infections].
Topics: Adult; Aged; Anti-Infective Agents; Chronic Disease; Drug Resistance, Microbial; Drug Synergism; Exa | 1971 |