trimethoprim has been researched along with Equine Diseases in 30 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Horses with lower respiratory tract infections caused by S equi subsp zooepidemicus were treated with a new formulation of combined trimethoprim-sulfadiazine oral suspension at a dosage of 24 mg/kg (10." | 5.20 | A randomized controlled field trial of a novel trimethoprim-sulfadiazine oral suspension for treatment of Streptococcus equi subsp zooepidemicus infection of the lower respiratory tract in horses. ( Hawkins, PA; Koenig, R; McClure, SR, 2015) |
| "Trimethoprim/sulfadiazine treatment resulted in a marked reduction of viable bacteria in the tissue chamber but did not eliminate the infection, resulting in abscessation from day 19 onwards in all six ponies." | 1.33 | Clinical efficacy of prophylactic administration of trimethoprim/sulfadiazine in a Streptococcus equi subsp. zooepidemicus infection model in ponies. ( Bosch, G; Ensink, JM; van Duijkeren, E, 2005) |
| "Pyrimethamine was coccidiocidal at 1." | 1.30 | Determination of the activity of pyrimethamine, trimethoprim, sulfonamides, and combinations of pyrimethamine and sulfonamides against Sarcocystis neurona in cell cultures. ( Dubey, JP; Lindsay, DS, 1999) |
| " No adverse effects other than loose faeces and diarrhoea were detected." | 1.29 | Side effects of oral antimicrobial agents in the horse: a comparison of pivampicillin and trimethoprim/sulphadiazine. ( Barneveld, A; Ensink, JM; Klein, WR; van Miert, AS; Vulto, AG, 1996) |
| " Administration of the TMP-SDZ combination at a dosage of 30 mg/kg once daily was not effective in maintaining TMP or SDZ concentrations above the MIC of TMP-SDZ for the S aureus (0." | 1.27 | Serum and synovial fluid steady-state concentrations of trimethoprim and sulfadiazine in horses with experimentally induced infectious arthritis. ( Bertone, AL; Jones, RL; McIlwraith, CW, 1988) |
| " The route of administration, size of the dose and dosing interval must be appropriate for the drug preparation selected." | 1.27 | Antimicrobial selection and dosage in the treatment of equine bacterial infections. ( Baggot, JD; Prescott, JF, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (23.33) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 4 (13.33) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Collinet, A | 1 |
| Grimm, P | 1 |
| Jacotot, E | 1 |
| Julliand, V | 1 |
| Potocnik, E | 1 |
| Drozdzewska, K | 1 |
| Schwarz, B | 1 |
| Johns, IC | 1 |
| Adams, EL | 1 |
| McClure, SR | 1 |
| Koenig, R | 1 |
| Hawkins, PA | 1 |
| Stack, A | 1 |
| Schott, HC | 1 |
| Ensink, JM | 3 |
| Smit, JA | 1 |
| van Duijkeren, E | 4 |
| Bosch, G | 1 |
| Katz, L | 1 |
| Divers, TJ | 2 |
| Byars, TD | 1 |
| Murch, O | 1 |
| Sigel, CW | 1 |
| Fey, K | 1 |
| Schmid, P | 1 |
| Golland, LC | 1 |
| Hodgson, DR | 1 |
| Davis, RE | 1 |
| Rawlinson, RJ | 1 |
| Collins, MB | 1 |
| McClintock, SA | 1 |
| Hutchins, DR | 1 |
| Rohner, K | 1 |
| Demuth, D | 1 |
| Vulto, AG | 3 |
| Van Miert, AS | 3 |
| Smith, JC | 1 |
| de Groot, J | 1 |
| Sloet van Oldruitenborgh-Oosterbaan, MM | 2 |
| van der Linda-Sipman, JS | 1 |
| Kalsbeek, HC | 1 |
| Klein, WR | 1 |
| Barneveld, A | 1 |
| Hillyer, MH | 1 |
| Innes, JF | 1 |
| Patteson, MW | 1 |
| Barr, AR | 1 |
| Breukink, HJ | 1 |
| Hawkins, JF | 1 |
| Lescun, TB | 1 |
| Dechan, J | 1 |
| Sertich, PL | 1 |
| Pozor, MA | 1 |
| Meyers, SA | 1 |
| Brown, JS | 1 |
| Lindsay, DS | 1 |
| Dubey, JP | 1 |
| Peek, SF | 1 |
| Gray, LC | 1 |
| Magdesian, KG | 1 |
| Sturges, BK | 1 |
| Madigan, JE | 1 |
| El Sanousi, SM | 1 |
| El Tayeb Amna, B | 1 |
| Shadad, EY | 1 |
| Bertone, AL | 1 |
| Jones, RL | 1 |
| McIlwraith, CW | 1 |
| Baggot, JD | 1 |
| Prescott, JF | 1 |
| Ikeda, JS | 1 |
| Hirsh, DC | 1 |
| Vaala, WE | 1 |
| Fubini, SL | 1 |
| Todhunter, RJ | 1 |
| Vivrette, SL | 1 |
| Hackett, RP | 1 |
3 reviews available for trimethoprim and Equine Diseases
| Article | Year |
|---|---|
Trimethoprim/sulfonamide combinations in the horse: a review.
Topics: Animals; Bacterial Infections; Drug Therapy, Combination; Horse Diseases; Horses; Sulfonamides; Trim | 1994 |
[Heart diseases in foals. A literature review exemplified by 2 case reports].
Topics: Animals; Drug Combinations; Endocarditis; Heart Defects, Congenital; Heart Diseases; Horse Diseases; | 1996 |
Aspects of pharmacology in the neonatal foal.
Topics: Aminoglycosides; Animals; Animals, Newborn; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infla | 1985 |
3 trials available for trimethoprim and Equine Diseases
| Article | Year |
|---|---|
A randomized controlled field trial of a novel trimethoprim-sulfadiazine oral suspension for treatment of Streptococcus equi subsp zooepidemicus infection of the lower respiratory tract in horses.
Topics: Administration, Oral; Animals; Drug Combinations; Female; Horse Diseases; Horses; Male; Respiratory | 2015 |
Clinical efficacy of trimethoprim/sulfadiazine and procaine penicillin G in a Streptococcus equi subsp. zooepidemicus infection model in ponies.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Drug Combinations; Drug Therapy, Combination; | 2003 |
A survey of horses with acute diarrhoea: diagnosis, assessment of the prognosis, and comparison of two antibiotic therapies.
Topics: Acute Disease; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Appetite; Blood Vo | 1996 |
24 other studies available for trimethoprim and Equine Diseases
| Article | Year |
|---|---|
Biomarkers for monitoring the equine large intestinal inflammatory response to stress-induced dysbiosis and probiotic supplementation.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biomarkers; Dietary Supplements; Dysbiosis; Fatty Acids; H | 2022 |
Presumed Sulfonamide-Associated Uveitis With Stevens-Johnson Syndrome in a Quarter Horse Mare.
Topics: Acinetobacter; Animals; Female; Horse Diseases; Horses; Stevens-Johnson Syndrome; Sulfanilamide; Sul | 2019 |
Trends in antimicrobial resistance in equine bacterial isolates: 1999-2012.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Enrof | 2015 |
Suspect novel adverse drug reactions to trimethoprim-sulphonamide combinations in horses: a case series.
Topics: Animals; Anti-Bacterial Agents; Central Nervous System Diseases; Drug Overdose; Drug Therapy, Combin | 2011 |
Clinical efficacy of prophylactic administration of trimethoprim/sulfadiazine in a Streptococcus equi subsp. zooepidemicus infection model in ponies.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Disease Models, Animal | 2005 |
Left otitis media/interna and right maxillary sinusitis in a Percheron mare.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Dimethyl Sulfoxide; Drug Combinations; Fac | 2006 |
Experimental induction of Proteus mirabilis cystitis in the pony and evaluation of therapy with trimethoprim-sulfadiazine.
Topics: Administration, Oral; Animals; Cystitis; Drug Combinations; Female; Horse Diseases; Horses; Nitrofur | 1981 |
[Susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine and combinations of these compounds].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Enterobacter; Esche | 1995 |
Retropharyngeal lymph node infection in horses: 46 cases (1977-1992).
Topics: Administration, Oral; Animals; Drainage; Drug Therapy, Combination; Female; Horse Diseases; Horses; | 1995 |
[Adverse effects of veterinary drugs].
Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dipyrone; Dog Diseases; Dogs; Drug Combinations; | 1994 |
Osteitis and sequestrum formation of the interdental region of the mandible in 11 polo ponies.
Topics: Animals; Anti-Infective Agents; Dogs; Drug Combinations; Female; Horse Diseases; Horses; Mandibular | 1993 |
Side effects of oral antimicrobial agents in the horse: a comparison of pivampicillin and trimethoprim/sulphadiazine.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Diarrhea; Drug Combinations; Female; Horse Dis | 1996 |
Discospondylitis in an adult horse.
Topics: Animals; Discitis; Drug Combinations; Horse Diseases; Horses; Male; Sulfadoxine; Thoracic Vertebrae; | 1996 |
Sepsis of the common digital extensor tendon sheath secondary to hemicircumferential periosteal transection in a foal.
Topics: Animals; Anti-Bacterial Agents; Combined Modality Therapy; Forelimb; Gentamicins; Horse Diseases; Ho | 1997 |
Combination of medical and surgical therapy for pleuropneumonia in a horse.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antitrichomonal Agents; Cep | 1997 |
Medical management of urinary calculi in a stallion with breeding dysfunction.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Anti-Inflamma | 1998 |
Determination of the activity of pyrimethamine, trimethoprim, sulfonamides, and combinations of pyrimethamine and sulfonamides against Sarcocystis neurona in cell cultures.
Topics: Animals; Anti-Infective Agents; Antimetabolites; Antiprotozoal Agents; Cattle; Cells, Cultured; Drug | 1999 |
Medical treatment of cholangiohepatitis and cholelithiasis in mature horses: 9 cases (1991-1998).
Topics: Animals; Anti-Infective Agents; Cephalosporins; Cholangitis; Cholelithiasis; Drug Combinations; Enro | 2000 |
Suspected protozoal myeloencephalitis in a two-month-old colt.
Topics: Animals; Animals, Newborn; Antibodies, Protozoan; Antiprotozoal Agents; Blotting, Western; Diagnosis | 2001 |
Bacteria isolated from uterine washings from mares in the Sudan.
Topics: Animals; Bacteria; Bacterial Infections; Female; Horse Diseases; Horses; Infertility, Female; Pregna | 1979 |
Serum and synovial fluid steady-state concentrations of trimethoprim and sulfadiazine in horses with experimentally induced infectious arthritis.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Arthritis, Infectious; Disease Models, Animal; | 1988 |
Antimicrobial selection and dosage in the treatment of equine bacterial infections.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Horse | 1987 |
Common plasmid encoding resistance to ampicillin, chloramphenicol, gentamicin, and trimethoprim-sulfadiazine in two serotypes of Salmonella isolated during an outbreak of equine salmonellosis.
Topics: Ampicillin; Animals; Anti-Infective Agents, Urinary; Chloramphenicol; Conjugation, Genetic; Disease | 1985 |
Tracheal rupture in two horses.
Topics: Animals; Anti-Infective Agents, Urinary; Bandages; Combined Modality Therapy; Drug Combinations; Emp | 1985 |