trimethoprim has been researched along with ENT Diseases in 22 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The new sulfa-trimethoprim combination showed activity similar to the reference drug, but it may have the advantage of a simpler dosage schedule." | 2.65 | Double-blind comparative trial of trimethoprim/sulfamethopyrazine once daily vs erythromycin 4 X daily in patients with ENT infections. ( Federspil, P; Koch, J, 1983) |
| "It was administered for the treatment of urinary tract infections (n = 125), bronchial infections (n = 24), intestinal infections (n = 25) and ENT infections (n = 37)." | 1.26 | [Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)]. ( Bulla, M; Helwig, H; Loh, K; Schreier, K; Sitzmann, W; Wodetzky, A, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Romanet, P | 1 |
| Federspil, P | 1 |
| Koch, J | 1 |
| Coudray, C | 1 |
| Camuzet, JP | 1 |
| De Braquilanges, E | 1 |
| Cornec, C | 1 |
| Bourguet, J | 1 |
| Dubreuil, C | 1 |
| Pignal, JL | 1 |
| Joly, B | 1 |
| Sirot, D | 1 |
| Cluzel, M | 1 |
| Chanal, M | 1 |
| Bruneau, D | 1 |
| Schwartz, RH | 1 |
| Serra, A | 1 |
| Tringali, G | 1 |
| Toscano, MA | 1 |
| Gismondo, MR | 1 |
| Piaia, F | 1 |
| Helwig, H | 1 |
| Bulla, M | 1 |
| Sitzmann, W | 1 |
| Schreier, K | 1 |
| Loh, K | 1 |
| Wodetzky, A | 1 |
| Winterbauer, RH | 1 |
| Etzel, M | 1 |
| Neuhof, F | 1 |
| Wesenberg, W | 1 |
| Quick, CA | 1 |
| Steinböck, VH | 1 |
| Sischka, O | 1 |
| Lenoir, JL | 1 |
| Pardes, P | 1 |
| Verhulst, J | 1 |
| Jacquemard, C | 1 |
| Ariano, M | 1 |
| Mesure, R | 1 |
| Chüden, HG | 1 |
| Callegari, E | 1 |
| Usoz, O | 1 |
| Diaz, A | 1 |
| Hongre, JF | 1 |
| Farriaux, JP | 1 |
| Fontaine, G | 1 |
| Gignoux, M | 1 |
| Gignoux, B | 1 |
| Chalard, R | 1 |
| Trepsat, F | 1 |
| Engelbert, J | 1 |
5 trials available for trimethoprim and ENT Diseases
| Article | Year |
|---|---|
Double-blind comparative trial of trimethoprim/sulfamethopyrazine once daily vs erythromycin 4 X daily in patients with ENT infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Drug A | 1983 |
[Trial of a new bactericide: Quam, in infectious otorhinolaryngologic pathology].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; Female; | 1981 |
[Clinical trial of the antibacterial combination sulfamoxole/trimethoprim (CN 3123)/Third communication: Clinical results of a field trial with CN 3123 in bronchopulmonary and ENT (ear/nose/throat) infections (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Child; Chronic Disease; Clinical Trials as Topic; Drug Combination | 1976 |
Comparison of penicillin and trimethoprim-sulfamethoxazole in the treatment of ear, nose and throat infections.
Topics: Adolescent; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; Drug Evalua | 1975 |
[Double-blind study of the association of sulfamethoxazole and trimethoprim in otorhinolaryngological infections].
Topics: Anti-Infective Agents; Bacterial Infections; Drug Combinations; Drug Synergism; Folic Acid Antagonis | 1973 |
17 other studies available for trimethoprim and ENT Diseases
| Article | Year |
|---|---|
[Trial of pediatric quam in common ORL. infections in children].
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Female; Humans; Infections; Male; Otorhinola | 1982 |
[Clinical study of Supristol in the treatment of acute infections in otorhinolaryngology].
Topics: Acute Disease; Adult; Aged; Child; Communicable Diseases; Cross Infection; Drug Combinations; Drug R | 1981 |
[Comparative activity of sulfamethoxazole-trimethoprim (SMZ-TMP) on bacteria responsible for ORL infections].
Topics: Ampicillin; Bacteria; Drug Combinations; Haemophilus; Humans; Microbial Sensitivity Tests; Oleandomy | 1984 |
The sulfonamides.
Topics: Bacterial Infections; Drug Combinations; Erythromycin; Humans; Otorhinolaryngologic Diseases; Sulfam | 1981 |
[Antibacterial activity of a sulfonamide combination (Kelfiprim) in some otorhinolaryngological diseases].
Topics: Acute Disease; Adolescent; Adult; Bacteria; Bacterial Infections; Chronic Disease; Drug Combinations | 1980 |
[Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)].
Topics: Child; Child, Preschool; Drug Combinations; Drug Eruptions; Enteritis; Humans; Infant; Otorhinolaryn | 1976 |
Comments on current antibiotic therapy.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Clindamycin; Drug | 1979 |
[Experience with a combination of sulfametrol and trimethoprim (Lidaprim) in otorhinilaryngologic infections].
Topics: Adolescent; Adult; Age Factors; Aged; Bacterial Infections; Child; Child, Preschool; Drug Therapy, C | 1975 |
[Evaluation of the use of the combination sulfamethoxazole-trimethoprim-ornidazole in the prevention of infections in major ORL surgery and otoneurosurgery (on 100 cases)].
Topics: Adult; Aged; Bacterial Infections; Drug Combinations; Female; Humans; Male; Middle Aged; Neurosurger | 1985 |
[Clinical trial of Bactrim in otorhinolaryngology].
Topics: Adolescent; Adult; Anti-Infective Agents; Drug Synergism; Drug Tolerance; Humans; Middle Aged; Otorh | 1971 |
[Results obtained with the combination of trimethoprim (2,4-diamino-3[3,4,5]-pyrimidine) and sulfamethoxazole (5-methyl-3-sulfanylamidoxazole) in the treatment of acute infections of otorhinolaryngologic import].
Topics: Acute Disease; Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Drug Combinations; | 1973 |
[Experimentation with the sulfamethoxazole-trimethoprim combination].
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Female; Folic Acid Antagonists; Humans; | 1972 |
[Indications for trimethoprim in otorhinolaryngology].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Child; Drug Combinations; Drug | 1972 |
[Clinical experience with a trimethoprim-sulfamethoxazole combination in pediatrics].
Topics: Anti-Infective Agents; Child; Child, Preschool; Drug Synergism; Folic Acid Antagonists; Humans; Infa | 1971 |
[Value of Eusaprim suspension in pediatrics].
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Female; Folic Acid Antagonists; Gastroen | 1971 |
[Bactrim in otorhinolaryngology].
Topics: Adolescent; Adult; Anti-Infective Agents; Female; Folic Acid Antagonists; Humans; Male; Middle Aged; | 1971 |
[Pediatric clinical study on the trimethoprim-sulfamethoxazole assoication].
Topics: Administration, Oral; Anti-Infective Agents; Child; Child, Preschool; Drug Combinations; Folic Acid | 1971 |