trimethoprim has been researched along with Drug-Related Side Effects and Adverse Reactions in 17 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This exploratory study assessed the safety of the combination of sulfamethoxazole, trimethoprim and guaifenesin (STG) in adult and pediatric patients with acute bronchitis according to local labelling in Peru." | 7.91 | A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis. ( Carrasco, R; Casas, A; de Los Ríos, J; Diaz, ME; Falcon, M; Felix, E; Flores, M; Guerra, F; Iberico, C; Reyes, I; Sanchez-Gambetta, S, 2019) |
| "This exploratory study assessed the safety of the combination of sulfamethoxazole, trimethoprim and guaifenesin (STG) in adult and pediatric patients with acute bronchitis according to local labelling in Peru." | 3.91 | A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis. ( Carrasco, R; Casas, A; de Los Ríos, J; Diaz, ME; Falcon, M; Felix, E; Flores, M; Guerra, F; Iberico, C; Reyes, I; Sanchez-Gambetta, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, JM | 1 |
| Matsson, P | 1 |
| Bergström, CA | 1 |
| Norinder, U | 1 |
| Hoogstraate, J | 1 |
| Artursson, P | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Goldman, JL | 1 |
| van Haandel, L | 1 |
| Falcon, M | 1 |
| Iberico, C | 1 |
| Guerra, F | 1 |
| Reyes, I | 1 |
| Felix, E | 1 |
| Flores, M | 1 |
| de Los Ríos, J | 1 |
| Diaz, ME | 1 |
| Casas, A | 1 |
| Sanchez-Gambetta, S | 1 |
| Carrasco, R | 1 |
| Iaccheri, B | 1 |
| Fiore, T | 1 |
| Papadaki, T | 1 |
| Androudi, S | 1 |
| Janjua, S | 1 |
| Bhaila, I | 1 |
| Stephen Foster, C | 1 |
| Ognongo-Ibiaho, AN | 1 |
| Atanda, HL | 1 |
| Wormser, GP | 1 |
| Krupp, LB | 1 |
| Hanrahan, JP | 1 |
| Gavis, G | 1 |
| Spira, TJ | 1 |
| Cunningham-Rundles, S | 1 |
| Andreev, E | 1 |
| Koopman, M | 1 |
| Arisz, L | 1 |
| Heilmann, E | 1 |
| Masera, G | 1 |
| Baronciani, D | 1 |
| Conti, A | 1 |
| Jankovic, M | 1 |
| Uderzo, C | 1 |
| Mitchell, AS | 1 |
| Henry, DA | 1 |
| Sanson-Fisher, R | 1 |
| O'Connell, DL | 1 |
| Johnson, RA | 1 |
| Poskitt, EM | 1 |
| McQueen, EG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Multicentric and Observational Study of Safety of Sulfamethoxazole + Trimethoprim + Guaifenesin (Balsamic Bactrim) in Adult Patients With Acute Bronchitis[NCT02902640] | 52 participants (Actual) | Observational | 2016-11-15 | Completed | |||
| A Pilot, Multicentric and Observational Study of Safety of Sulfamethoxazole + Trimethoprim + Guaifenesin (Balsamic Bactrim) in Pediatric Patients With Acute Bronchitis[NCT02879981] | 51 participants (Actual) | Observational | 2016-11-10 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for trimethoprim and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
A rise in plasma creatinine that is not a sign of renal failure: which drugs can be responsible?
Topics: Adrenal Cortex Hormones; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvuls | 1999 |
[Drug-induced megaloblastic anemia].
Topics: Alcoholism; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Anticonvulsants; Antim | 1979 |
15 other studies available for trimethoprim and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi | 2008 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Trimethoprim: The overlooked component of trimethoprim-sulfamethoxazole idiosyncratic adverse drug reactions.
Topics: Adult; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Protein B | 2018 |
A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bronchitis; Child; Child, Preschool; Drug Combinations; | 2019 |
A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bronchitis; Child; Child, Preschool; Drug Combinations; | 2019 |
A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bronchitis; Child; Child, Preschool; Drug Combinations; | 2019 |
A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis.
Topics: Acute Disease; Adult; Anti-Infective Agents; Bronchitis; Child; Child, Preschool; Drug Combinations; | 2019 |
Adverse drug reactions to treatments for ocular toxoplasmosis: a retrospective chart review.
Topics: Adolescent; Adult; Atovaquone; Clindamycin; Drug Combinations; Drug-Related Side Effects and Adverse | 2008 |
Epidemiological study of fixed drug eruption in Pointe-Noire.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Child, Preschool; Congo; Counterfeit Drugs; D | 2012 |
Acquired immunodeficiency syndrome in male prisoners. New insights into an emerging syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candida albicans; Drug-Related Side Effects and Adverse R | 1983 |
[Hemopathies caused by drugs in children: aplastic anemia, agranulocytosis, megaloblastic anemia].
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; | 1978 |
Patients as a direct source of information on adverse drug reactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Infective Agents; Australia; Child; Ch | 1988 |
Adverse reactions in ten years' general practice, computer analysed.
Topics: Ampicillin; Computers; Contraceptives, Oral; Contraceptives, Oral, Combined; Drug Combinations; Drug | 1986 |
CSM update. Blood dyscrasias.
Topics: Adult; Age Factors; Aged; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Hemato | 1985 |
Clinical problems related to the use of drugs in malnutrition.
Topics: Child; Child Nutritional Physiological Phenomena; Chloramphenicol; Chloroquine; Drug-Related Side Ef | 1974 |
New Zealand Committee on Adverse Drug Reactions: Ninth Annual Report 1974.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Aged; Antineoplastic Agents; Drug Interactions; Drug | 1974 |