trimethoprim has been researched along with Diabetes Mellitus in 5 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since diabetics frequently suffer from urinary tract infections which can be successfully treated with a combination of sulphonamide derivatives and the bacteriocide trimethoprim, the question of possible interactions between such agents and diabetic therapy is of interest." | 5.05 | [An absence of interaction of sulfametrol-trimethoprim with insulin or sulphonylurea derivatives in diabetics (author's transl)]. ( Kaspar, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niemi, M | 1 |
| Kajosaari, LI | 1 |
| Neuvonen, M | 1 |
| Backman, JT | 1 |
| Neuvonen, PJ | 1 |
| Kaspar, L | 1 |
| Etzel, M | 1 |
| Wesenberg, W | 1 |
| Mihic, M | 1 |
| Mautner, LS | 1 |
| Feness, JZ | 1 |
| Grant, K | 1 |
| Schwedes, U | 1 |
| Haupt, E | 1 |
| Bartelt, KM | 1 |
| Beyer, J | 1 |
| Schöffling, K | 1 |
3 trials available for trimethoprim and Diabetes Mellitus
| Article | Year |
|---|---|
The CYP2C8 inhibitor trimethoprim increases the plasma concentrations of repaglinide in healthy subjects.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbamates; Cross-Over Studies; Cytochrome | 2004 |
[An absence of interaction of sulfametrol-trimethoprim with insulin or sulphonylurea derivatives in diabetics (author's transl)].
Topics: Diabetes Complications; Diabetes Mellitus; Drug Interactions; Female; Humans; Insulin; Middle Aged; | 1980 |
[Clinical trial of the antibacterial combination sulfamoxole/trimethoprim (CN 3123)/Sixth communication: Results of compatibility of CN 3123 (author's transl)].
Topics: Adolescent; Adult; Aged; Blood Glucose; Child; Child, Preschool; Clinical Trials as Topic; Diabetes | 1976 |
2 other studies available for trimethoprim and Diabetes Mellitus
| Article | Year |
|---|---|
Effect of trimethoprim-sulfamethoxazole on blood insulin and glucose concentrations of diabetics.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus; Drug Combinations; Humans; Hypoglycemic Agen | 1975 |
[Effect of a combined antibacterial therapy using sulfamethoxazole and trimethoprim on the metabolism of diabetics].
Topics: Diabetes Mellitus; Drug Combinations; Humans; Sulfamethoxazole; Trimethoprim; Urinary Tract Infectio | 1974 |