Page last updated: 2024-11-05

trimethoprim and Dermatitis Medicamentosa

trimethoprim has been researched along with Dermatitis Medicamentosa in 66 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Research Excerpts

ExcerptRelevanceReference
"The efficacy of orally administered trimethoprim-sulfamethoxazole was compared with that of oral amoxicillin in therapy of typhoid fever due to both epidemic chloramphenicol-resistant and endemic chloramphenicol-sensitive Salmonella typhi."9.04Comparison of trimethoprim-sulfamethoxazole and amoxicillin in therapy of chloramphenicol-resistant and chloramphenicol-sensitive typhoid fever. ( Calderone, E; Gilman, RH; Hernandez-Mendosa, P; Hornick, RB; Levine, MM; Martinez, E; Snyder, MJ; Terminel, M; Vasquez, V, 1975)
" Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation."7.67Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984)
"In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy."7.67Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989)
"All patients with the acquired immunodeficiency syndrome and a first episode of Pneumocystis carinii pneumonia seen at the San Francisco General Hospital between November 1984 and April 1985 were evaluated for oral treatment with dapsone (100 mg/d) plus trimethoprim (20 mg/kg body weight X d)."7.67Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. ( Hopewell, PC; Hughes, W; Leoung, GS; Mills, J; Wofsy, C, 1986)
"These results suggest a drug exanthema, in all probability triggered by the leech therapy."5.33[Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy]. ( Beer, AM; Ciborovius, J; Fey, S; Knorr, M, 2005)
"The efficacy of orally administered trimethoprim-sulfamethoxazole was compared with that of oral amoxicillin in therapy of typhoid fever due to both epidemic chloramphenicol-resistant and endemic chloramphenicol-sensitive Salmonella typhi."5.04Comparison of trimethoprim-sulfamethoxazole and amoxicillin in therapy of chloramphenicol-resistant and chloramphenicol-sensitive typhoid fever. ( Calderone, E; Gilman, RH; Hernandez-Mendosa, P; Hornick, RB; Levine, MM; Martinez, E; Snyder, MJ; Terminel, M; Vasquez, V, 1975)
"We present two patients who experienced life-threatening immediate reactions and one patient who developed generalized urticaria following oral administration of trimethoprim (TMP) and sulfamethoxazole (SMX) combination."3.68Hypersensitivity to trimethoprim. ( Alonso, MD; Davila, I; de la Hoz, B; Diez, ML; Marcos, C; Martin, JA; Parra, F, 1992)
" Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation."3.67Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984)
" In the second patient, a radiodermatitis of the left upper arm due to electron beam therapy for metastatic breast cancer was followed 7 weeks later by a codeine drug reaction confined to the area of the radiodermatitis."3.67Drug eruptions presenting at sites of prior radiation damage (sunlight and electron beam). ( Campbell, AC; Shelley, ED; Shelley, WB; Weigensberg, IJ, 1984)
"In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy."3.67Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989)
"All patients with the acquired immunodeficiency syndrome and a first episode of Pneumocystis carinii pneumonia seen at the San Francisco General Hospital between November 1984 and April 1985 were evaluated for oral treatment with dapsone (100 mg/d) plus trimethoprim (20 mg/kg body weight X d)."3.67Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. ( Hopewell, PC; Hughes, W; Leoung, GS; Mills, J; Wofsy, C, 1986)
"The onset of cutaneous adverse effects attributable to sulfamethoxazole-trimethoprim therapy within 3 months after desensitization."2.68Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus. ( Bricaire, F; Caumes, E; Guermonprez, G; Katlama, C; Lecomte, C, 1997)
"Treatment with trimethoprim reduced significantly the periurethral colonization of Escherichia coli."2.65Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine. ( Brumfitt, W; Cooper, J; Gargan, RA; Hamilton-Miller, JM; Smith, GW, 1983)
"These results suggest a drug exanthema, in all probability triggered by the leech therapy."1.33[Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy]. ( Beer, AM; Ciborovius, J; Fey, S; Knorr, M, 2005)
"We studied an acute generalized exanthematous pustulosis (AGEP) due to sulfamethoxazol in a 48-year-old woman with unusual findings in allergy testing."1.32Acute generalized exanthematous pustulosis due to sulfamethoxazol with positive lymphocyte transformation test (LTT). ( Anliker, MD; Wüthrich, B, 2003)
"Thirty-four homosexual patients with AIDS were treated for Pneumocystis carinii pneumonia between April 1984 and November 1985."1.28Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions. ( Seitzman, PA; Shafer, RW; Tapper, ML, 1989)
"Clinical features of 49 episodes of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome were compared with those of 39 episodes in patients with other immunosuppressive diseases."1.27Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. ( Hiemenz, JW; Honig, C; Kovacs, JA; Lane, HC; Longo, DL; Macher, AM; Murray, HW; Shelhamer, J; Stover, D; Urmacher, C, 1984)
"It was administered for the treatment of urinary tract infections (n = 125), bronchial infections (n = 24), intestinal infections (n = 25) and ENT infections (n = 37)."1.26[Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)]. ( Bulla, M; Helwig, H; Loh, K; Schreier, K; Sitzmann, W; Wodetzky, A, 1976)
" Long-term administration does not per se seem to represent an additional hazard provided the dose is the correct one and the hematologic monitoring of the patient is performed regularly."1.25Adverse reactions to trimethoprim-sulfamethoxazole, with particular reference to long-term therapy. ( Bernstein, LS, 1975)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199048 (72.73)18.7374
1990's10 (15.15)18.2507
2000's5 (7.58)29.6817
2010's1 (1.52)24.3611
2020's2 (3.03)2.80

Authors

AuthorsStudies
Connolly, A1
Walsh, S1
Philippidou, M1
Salisbury, J1
Creamer, D1
Pereira, ARF1
Aun, MV1
Kelmann, NCP1
Motta, AA1
Kalil, J1
Giavina-Bianchi, P1
Moreno Escobosa, MC1
Cruz Granados, S1
Moya Quesada, MC1
Amat López, J1
Ognongo-Ibiaho, AN1
Atanda, HL1
Anliker, MD1
Wüthrich, B1
Beer, AM1
Fey, S1
Ciborovius, J1
Knorr, M1
Shimanovich, I1
Rose, C1
Zillikens, D1
Grabbe, J1
Kauppinen, K1
Stubb, S1
Gibson, JR1
Mitsuyasu, R1
Groopman, J1
Volberding, P1
Bartram, R1
Kastrup, J1
Andersen, C1
Brumfitt, W1
Hamilton-Miller, JM1
Gargan, RA1
Cooper, J1
Smith, GW1
Gordin, FM1
Simon, GL1
Wofsy, CB1
Mills, J2
Kovacs, JA1
Hiemenz, JW1
Macher, AM1
Stover, D1
Murray, HW1
Shelhamer, J1
Lane, HC1
Urmacher, C1
Honig, C1
Longo, DL1
Shelley, WB1
Shelley, ED1
Campbell, AC1
Weigensberg, IJ1
Nagy, G1
Meszáros, A1
Deroń, Z1
Jabłkowski, M1
Talbot, MD1
Noli, C1
Koeman, JP1
Willemse, T1
Caumes, E1
Guermonprez, G1
Lecomte, C1
Katlama, C1
Bricaire, F1
Feeney, J1
Ozkaya-Bayazit, E4
Baykal, C1
Hattori, N1
Hino, H1
Güngör, H1
Usatine, RP1
Bayazit, H2
Ozarmagan, G2
Wãhlin, A1
Rosman, N1
Finlayson, WB1
Johnson, G1
Bernstein, LS1
Gilman, RH1
Terminel, M1
Levine, MM1
Hernandez-Mendosa, P1
Calderone, E1
Vasquez, V1
Martinez, E1
Snyder, MJ1
Hornick, RB1
Krivanek, J1
Doyle, J1
Paver, K1
Kossard, S1
Helwig, H1
Bulla, M1
Sitzmann, W1
Schreier, K1
Loh, K1
Wodetzky, A1
Knudsen, L1
Weismann, K1
Kasanen, A1
Anttila, M1
Elfving, R1
Kahela, P1
Saarimaa, H1
Sundquist, H1
Tikkanen, R1
Toivanen, P1
Beck, MH1
Portnoy, B1
Lim, JT1
Chan, HL1
Alonso, MD1
Marcos, C1
Davila, I1
de la Hoz, B1
Martin, JA1
Parra, F1
Diez, ML1
White, MV1
Haddad, ZH1
Brunner, E1
Sainz, C1
Liddle, BJ1
Marsden, JR1
Shafer, RW1
Seitzman, PA1
Tapper, ML1
Varsano, I2
Amir, Y1
Rudra, T1
Webb, DB1
Evans, AG1
Sawada, Y1
Chandler, MJ1
Leoung, GS1
Hopewell, PC1
Hughes, W1
Wofsy, C1
Amir, J1
Shuper, A1
Livni, E1
Mimouni, M1
Hughes, BR1
Holt, PJ1
Marks, R1
Verhagen, C1
Stalpers, LJ1
de Pauw, BE1
Haanen, C1
Colebunders, R1
Izaley, L1
Bila, K1
Kabumpangi, K1
Melameka, N1
Francis, H1
Curran, JW1
Ryder, R1
Piot, P1
Schöpf, E1
Van Voorhees, A1
Stenn, KS1
Bharija, SC1
Singh, M1
Belhaj, MS1
Borucki, MJ1
Matzke, DS1
Pollard, RB1
De Raeve, L1
Song, M1
Van Maldergem, L1
DeHovitz, JA1
Johnson, WD1
Pape, JW1
Klein, U1
Gikalov, I1
Keller, M1
Hoigné, R1
Halpern, G1
Halpern, GM1
Dungan, RW1
Navarro, J1
Salter, AJ1
Frisch, JM1
Marks, MI1
Kazemi, M1
Hales, B1
Neims, AH1
Drach, GW1
D'Alessandro, L1
Faenza, L1
Di Palma, D1
Russo, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing Due to New Episodes of Urinary Tract Infections (UTI) in Elderly Women With Recurrent UTI - a Triple- Blinded, Randomized Placebo-controlled Phase IV Study[NCT04077580]Phase 4400 participants (Anticipated)Interventional2019-11-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for trimethoprim and Dermatitis Medicamentosa

ArticleYear
Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine.
    The Journal of urology, 1983, Volume: 130, Issue:6

    Topics: Administration, Topical; Adult; Clinical Trials as Topic; Drug Eruptions; Drug Resistance, Microbial

1983
Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus.
    Archives of dermatology, 1997, Volume: 133, Issue:4

    Topics: Adult; Anti-Infective Agents; Desensitization, Immunologic; Drug Administration Schedule; Drug Erupt

1997
Comparison of trimethoprim-sulfamethoxazole and amoxicillin in therapy of chloramphenicol-resistant and chloramphenicol-sensitive typhoid fever.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:6

    Topics: Adolescent; Adult; Amoxicillin; Ampicillin; Child; Chloramphenicol; Clinical Trials as Topic; Drug C

1975
Trimethoprim. Pharmacology, antimicrobial activity and clinical use in urinary tract infections.
    Annals of clinical research, 1978, Volume: 10 Suppl 22

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Dose-Respons

1978
[Trimethoprim-sulfamethoxazole (TM-SMZ) combination in the treatment of brucellosis].
    Minerva medica, 1974, May-30, Volume: 65, Issue:41

    Topics: Adolescent; Adult; Aged; Brucellosis; Clinical Trials as Topic; Drug Combinations; Drug Eruptions; D

1974

Other Studies

61 other studies available for trimethoprim and Dermatitis Medicamentosa

ArticleYear
Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS).
    The British journal of dermatology, 2023, 07-07, Volume: 189, Issue:1

    Topics: Drug Eruptions; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Liver Failure, Acut

2023
Loss of tolerance 5 days after discontinuing sulphonamide introduced via desensitization in delayed reaction.
    Einstein (Sao Paulo, Brazil), 2020, Volume: 18

    Topics: Aged; Desensitization, Immunologic; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Sulfamethox

2020
Enanthema and fixed drug eruption caused by trimethoprim.
    Journal of investigational allergology & clinical immunology, 2009, Volume: 19, Issue:3

    Topics: Anti-Bacterial Agents; Drug Eruptions; Humans; Male; Middle Aged; Patch Tests; Sulfamethoxazole; Tri

2009
Epidemiological study of fixed drug eruption in Pointe-Noire.
    International journal of dermatology, 2012, Volume: 51 Suppl 1

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Child, Preschool; Congo; Counterfeit Drugs; D

2012
Acute generalized exanthematous pustulosis due to sulfamethoxazol with positive lymphocyte transformation test (LTT).
    Journal of investigational allergology & clinical immunology, 2003, Volume: 13, Issue:1

    Topics: Administration, Topical; Anti-Infective Agents; Anti-Inflammatory Agents; Betamethasone; Drug Erupti

2003
[Drug exanthema in connection with trimethoprim and sulfamethoxazole treatment, triggered by leech therapy].
    Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine, 2005, Volume: 12, Issue:1

    Topics: Anti-Infective Agents; Drug Eruptions; Exanthema; Female; Humans; Leeching; Lymphocyte Activation; M

2005
Erythema and blistering of the left leg. Fixed drug eruption (FDE).
    Archives of dermatology, 2007, Volume: 143, Issue:4

    Topics: Aged, 80 and over; Anti-Infective Agents, Urinary; Drug Eruptions; Erythema; Female; Humans; Leg Der

2007
Drug eruptions: causative agents and clinical types. A series of in-patients during a 10-year period.
    Acta dermato-venereologica, 1984, Volume: 64, Issue:4

    Topics: Ampicillin; Anti-Bacterial Agents; Barbiturates; Drug Eruptions; Humans; Penicillins; Stevens-Johnso

1984
Recurrent trimethoprim-associated fixed skin eruption.
    British medical journal (Clinical research ed.), 1982, May-22, Volume: 284, Issue:6328

    Topics: Drug Eruptions; Female; Humans; Middle Aged; Recurrence; Trimethoprim; Urinary Tract Infections

1982
Cutaneous reaction to trimethoprim-sulfamethoxazole in patients with AIDS and Kaposi's sarcoma.
    The New England journal of medicine, 1983, Jun-23, Volume: 308, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Eruptions; Humans; Pneumonia, Pneumocyst

1983
[Erythema nodosum following trimethoprim treatment].
    Ugeskrift for laeger, 1983, Apr-04, Volume: 145, Issue:14

    Topics: Drug Eruptions; Erythema Nodosum; Female; Humans; Middle Aged; Trimethoprim

1983
Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1984, Volume: 100, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Eruptions; Drug Hypersensitivity;

1984
Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies.
    Annals of internal medicine, 1984, Volume: 100, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Child; Drug Combinations; Drug Eruption

1984
Drug eruptions presenting at sites of prior radiation damage (sunlight and electron beam).
    Journal of the American Academy of Dermatology, 1984, Volume: 11, Issue:1

    Topics: Adult; Breast Neoplasms; Codeine; Drug Combinations; Drug Eruptions; Female; Humans; Middle Aged; Ra

1984
[Acetylsalicylic acid intolerance in Lyell syndrome].
    Dermatologische Monatschrift, 1984, Volume: 170, Issue:5

    Topics: Aspirin; Drug Combinations; Drug Eruptions; Female; Humans; Middle Aged; Respiratory Tract Infection

1984
[Side effects of toxoplasmosis treatment].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Jun-09, Volume: 35, Issue:23

    Topics: Adolescent; Adult; Anemia; Antiprotozoal Agents; Child; Child, Preschool; Drug Eruptions; Dyspepsia;

1980
Fixed genital drug eruption.
    The Practitioner, 1980, Volume: 224, Issue:1346

    Topics: Adult; Balanitis; Drug Combinations; Drug Eruptions; Humans; Male; Middle Aged; Penile Diseases; Ski

1980
A retrospective evaluation of adverse reactions to trimethoprim-sulphonamide combinations in dogs and cats.
    The veterinary quarterly, 1995, Volume: 17, Issue:4

    Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Combinations; Drug Erup

1995
Diaminopyrimidines and severe cutaneous adverse reactions.
    Archives of dermatology, 1997, Volume: 133, Issue:9

    Topics: Acute Disease; Anticonvulsants; Antimalarials; Drug Eruptions; Humans; Lamotrigine; Pyrimethamine; P

1997
Trimethoprim-induced linear fixed drug eruption.
    The British journal of dermatology, 1997, Volume: 137, Issue:6

    Topics: Adult; Arm; Drug Eruptions; Female; Folic Acid Antagonists; Humans; Trimethoprim

1997
Generalized erythematous skin eruptions due to trimethoprim itself and co-trimoxazole.
    The Journal of dermatology, 1998, Volume: 25, Issue:4

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Cystitis; Drug Eruptions; Erythema; Female; Humans; Mal

1998
Trimethoprim-induced fixed drug eruption: positive topical provocation on previously involved and uninvolved skin.
    Contact dermatitis, 1998, Volume: 39, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Drug Eruptions; Female; Humans; Patch Tests; Skin; Trimethoprim

1998
A 4-year-old girl with a rash and joint pain.
    The Western journal of medicine, 1999, Volume: 171, Issue:2

    Topics: Anti-Infective Agents; Arthralgia; Child, Preschool; Drug Eruptions; Female; Humans; IgA Vasculitis;

1999
Topical provocation in 27 cases of cotrimoxazole-induced fixed drug eruption.
    Contact dermatitis, 1999, Volume: 41, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Dose-Response Relationship, Drug; Drug Erupti

1999
Drug related clinical pattern in fixed drug eruption.
    European journal of dermatology : EJD, 2000, Volume: 10, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Infective Agents; Anti-Inflam

2000
Skin manifestations with vasculitis due to co-trimoxazole.
    Lancet (London, England), 1976, Dec-25, Volume: 2, Issue:8000

    Topics: Aged; Bronchitis; Drug Combinations; Drug Eruptions; Erythema; Humans; Male; Sulfamethoxazole; Trime

1976
Multisystem toxicity after co-trimoxazole.
    Lancet (London, England), 1978, Sep-23, Volume: 2, Issue:8091

    Topics: Acute Kidney Injury; Aged; Anuria; Drug Combinations; Drug Eruptions; Female; Hepatic Encephalopathy

1978
Adverse reactions to trimethoprim-sulfamethoxazole, with particular reference to long-term therapy.
    Canadian Medical Association journal, 1975, Jun-14, Volume: 112, Issue:13 Spec No

    Topics: Adult; Aged; Bacterial Infections; Blood Cell Count; Blood Cells; Blood Platelets; Child; Drug Combi

1975
A case report on the psoriatic sparing of a drug reaction.
    The Australasian journal of dermatology, 1975, Volume: 16, Issue:1

    Topics: Drug Eruptions; Female; Humans; Middle Aged; Psoriasis; Trimethoprim

1975
[Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)].
    Klinische Padiatrie, 1976, Volume: 188, Issue:6

    Topics: Child; Child, Preschool; Drug Combinations; Drug Eruptions; Enteritis; Humans; Infant; Otorhinolaryn

1976
[Pustular eruption and damage of internal organs after sulfamethoxazole combined with trimethoprim].
    Ugeskrift for laeger, 1977, Apr-25, Volume: 139, Issue:17

    Topics: Aged; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Eruptions; Humans; Kidney; Kid

1977
Severe erythema multiforme complicated by fatal gastrointestinal involvement following co-trimoxazole therapy.
    Clinical and experimental dermatology, 1979, Volume: 4, Issue:2

    Topics: Abdomen, Acute; Drug Combinations; Drug Eruptions; Erythema Multiforme; Female; Humans; Middle Aged;

1979
Fixed drug eruptions due to co-trimoxazole.
    Annals of the Academy of Medicine, Singapore, 1992, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Child; Drug Eruptions; Female; Humans; Male; Sulfamethoxazole; Trimethoprim; Trim

1992
Hypersensitivity to trimethoprim.
    Allergy, 1992, Volume: 47, Issue:4 Pt 1

    Topics: Adult; Drug Eruptions; Female; Humans; Respiratory Tract Infections; Trimethoprim; Trimethoprim, Sul

1992
Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia.
    Annals of allergy, 1989, Volume: 62, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Desensitizat

1989
Drug interactions with methotrexate.
    The British journal of dermatology, 1989, Volume: 120, Issue:4

    Topics: Aged; Drug Combinations; Drug Eruptions; Drug Interactions; Female; Humans; Leg Dermatoses; Methotre

1989
Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions.
    Journal of acquired immune deficiency syndromes, 1989, Volume: 2, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Cohort Studi

1989
Fixed drug eruption due to cotrimexasole.
    Dermatologica, 1989, Volume: 178, Issue:4

    Topics: Anti-Infective Agents; Drug Combinations; Drug Eruptions; Humans; Sulfamethoxazole; Trimethoprim; Tr

1989
Acute tubular necrosis following co-trimoxazole therapy.
    Nephron, 1989, Volume: 53, Issue:1

    Topics: Acute Kidney Injury; Aged; Drug Combinations; Drug Eruptions; Humans; Kidney; Kidney Tubular Necrosi

1989
Adverse reaction to sulphonamides in a burned patient--a case report.
    Burns, including thermal injury, 1985, Volume: 12, Issue:2

    Topics: Adult; Anti-Infective Agents, Urinary; Burns; Drug Combinations; Drug Eruptions; Humans; Male; Patch

1985
Recurrence of phototoxic skin eruption due to trimethoprim.
    The Journal of infectious diseases, 1986, Volume: 153, Issue:5

    Topics: Adult; Drug Eruptions; Female; Humans; Photosensitivity Disorders; Recurrence; Trimethoprim

1986
Dapsone-trimethoprim for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1986, Volume: 105, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Bronchoscopy; Dapsone; Drug Eruptions; Drug Therapy, Combination

1986
Fixed drug eruption of the penis due to co-trimoxazole.
    Drug intelligence & clinical pharmacy, 1987, Volume: 21, Issue:1 Pt 1

    Topics: Child; Child, Preschool; Drug Combinations; Drug Eruptions; Humans; Male; Penile Diseases; Sulfameth

1987
Trimethoprim associated fixed drug eruption.
    The British journal of dermatology, 1987, Volume: 116, Issue:2

    Topics: Adult; Drug Combinations; Drug Eruptions; Female; Humans; Sulfamethoxazole; Trimethoprim; Trimethopr

1987
Drug-induced skin reactions in patients with acute non-lymphocytic leukaemia.
    European journal of haematology, 1987, Volume: 38, Issue:3

    Topics: Acute Disease; Adult; Allopurinol; Cephalosporins; Drug Combinations; Drug Eruptions; Female; Humans

1987
Cutaneous reactions to trimethoprim-sulfamethoxazole in African patients with the acquired immunodeficiency syndrome.
    Annals of internal medicine, 1987, Volume: 107, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Black People; Democratic Republic of the Congo; Drug Combination

1987
Skin reactions to co-trimoxazole.
    Infection, 1987, Volume: 15 Suppl 5

    Topics: Anti-Infective Agents; Drug Combinations; Drug Eruptions; Humans; Skin; Stevens-Johnson Syndrome; Su

1987
Histological phases of Bactrim-induced fixed drug eruption. The report of one case.
    The American Journal of dermatopathology, 1987, Volume: 9, Issue:6

    Topics: Aged; Ampicillin; Anti-Infective Agents, Urinary; Biopsy; Drug Combinations; Drug Eruptions; Humans;

1987
Fixed drug eruption in an 8-month-old infant.
    Dermatologica, 1988, Volume: 176, Issue:2

    Topics: Drug Combinations; Drug Eruptions; Humans; Infant; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sul

1988
Tremor induced by trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome (AIDS).
    Annals of internal medicine, 1988, Jul-01, Volume: 109, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Ataxia; Drug Combinations; Drug Eruptions; Emotions; Huma

1988
Adverse cutaneous drug reactions in AIDS.
    The British journal of dermatology, 1988, Volume: 119, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Anti-Infective Agents; Drug Combinations; Drug Eruptions; Female

1988
Cutaneous reactions to trimethoprim-sulfamethoxazole in Haitians.
    Annals of internal medicine, 1985, Volume: 103, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Eruptions; Haiti; Humans; Sulfamethoxazo

1985
[Drug monitoring in the medical ward of a regional hospital].
    Schweizerische medizinische Wochenschrift, 1972, Aug-05, Volume: 102, Issue:31

    Topics: Adult; Ampicillin; Anticoagulants; Antidepressive Agents; Central Nervous System Stimulants; Chemica

1972
[Allergic reactons and composite drugs].
    La Presse medicale, 1971, Oct-16, Volume: 79, Issue:43

    Topics: Adult; Anti-Infective Agents; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Female; Foli

1971
Unusual reaction to trimethoprim in combined therapy.
    British medical journal, 1972, Mar-11, Volume: 1, Issue:5801

    Topics: Anti-Infective Agents; Asthma; Drug Eruptions; Female; Folic Acid Antagonists; Humans; Middle Aged;

1972
The use of trimethoprim-sulphamethoxazole in urinary tract infections in domiciliary practice.
    The Medical journal of Australia, 1973, Mar-17, Volume: 1, Issue:11

    Topics: Anti-Infective Agents; Bacteriuria; Child, Preschool; Chronic Disease; Drug Eruptions; Escherichia c

1973
[Biological tolerance of the trimethoprim-sulfamethoxazole combination in pediatrics. Its influence on serum folic and folinic acid levels].
    Therapeutique (La Semaine des hopitaux), 1972, Volume: 48, Issue:10

    Topics: Adolescent; Age Factors; Anti-Infective Agents; Bacterial Infections; Child; Child, Preschool; Drug

1972
The toxicity profile of trimethoprim-sulphamethoxazole after four years of widespread use.
    The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Anti-Infective Agents; Child; Child, Presch

1973
Clinical experience with adverse reactions to trimethoprim-sulfamethoxazole.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Aged; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Child; Depression; Drug Combinations; D

1973
Pharmacokinetic studies of trimethoprim-sulfamethoxazole in children with gastroenteritis.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Drug Eruptions; Dysentery, Bacillary; Gastro

1973
Trimethoprim sulfamethoxazole therapy of chronic bacterial prostatitis.
    The Journal of urology, 1974, Volume: 111, Issue:5

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Candidiasis, Oral; Child; Drug Eruptions; Escherichia

1974