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trimethoprim and Cytomegalovirus Infections

trimethoprim has been researched along with Cytomegalovirus Infections in 17 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Cytomegalovirus Infections: Infection with CYTOMEGALOVIRUS, characterized by enlarged cells bearing intranuclear inclusions. Infection may be in almost any organ, but the salivary glands are the most common site in children, as are the lungs in adults.

Research Excerpts

ExcerptRelevanceReference
"We investigated the pharmacokinetics and safety profile of oral ganciclovir coadministered with trimethoprim in HIV-and CMV-seropositive patients."9.09The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients. ( AbdelHameed, MH; Dorr, A; Griffy, K; Hunter, J; Jung, D; Teitelbaum, P, 1999)
"We investigated the pharmacokinetics and safety profile of oral ganciclovir coadministered with trimethoprim in HIV-and CMV-seropositive patients."5.09The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients. ( AbdelHameed, MH; Dorr, A; Griffy, K; Hunter, J; Jung, D; Teitelbaum, P, 1999)
"In MRC-5 cell cultures, the efficacy of the acyclic nucleoside ganciclovir (GCV) against human cytomegalovirus (CMV) was unaffected when combined with either amphotericin B (AMP B), ketoconazole (KCZ), dapsone (DAP), or trimethoprim/sulfamethoxazole (TMP/SMX)."1.29Efficacy of ganciclovir in combination with other antimicrobial agents against cytomegalovirus in vitro and in vivo. ( Fraser-Smith, EB; Freitas, VR; Matthews, TR, 1993)
"In 11 of these a diagnosis of AIDS was confirmed because of an alternative opportunistic infection within 6 months."1.28Diagnosis, treatment and outcome of pneumonia in the acquired immune deficiency syndrome. ( Collins, JV; Gardner, TD; Gazzard, BG; Griffiths, PD; Hanson, PJ; Youle, M, 1989)
"Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients."1.28[Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin]. ( Arai, Y; Ishida, A; Kim, CJ; Konishi, T; Kounami, T; Okino, K; Pak, K; Sako, H; Tomoyoshi, T; Wakabayashi, Y, 1989)
"The cause of AIDS is unknown."1.27Infectious complications of the acquired immune deficiency syndrome. ( Armstrong, D; Gold, JW, 1984)
"Pneumocystis carinii pneumonia has rarely been reported in previously healthy persons over the age of 6 months."1.26An outbreak of Pneumocystis carinii pneumonia in homosexual men. ( Aurigemma, GP; Busch, DF; Coleman, DL; Drew, WL; Follansbee, SE; Gullet, J; Hadley, WK; Ross, T; Wofsy, CB, 1982)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199011 (64.71)18.7374
1990's4 (23.53)18.2507
2000's1 (5.88)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goussard, P1
Kling, S1
Gie, RP1
Nel, ED1
Heyns, L1
Rossouw, GJ1
Janson, JT1
Peterson, PK1
Simmons, RL1
Gold, JW1
Armstrong, D1
Follansbee, SE1
Busch, DF1
Wofsy, CB1
Coleman, DL1
Gullet, J1
Aurigemma, GP1
Ross, T1
Hadley, WK1
Drew, WL1
Hardy, AM1
Wajszczuk, CP1
Suffredini, AF1
Hakala, TR1
Ho, M1
Murray, JF1
Felton, CP1
Garay, SM1
Gottlieb, MS1
Hopewell, PC1
Stover, DE1
Teirstein, AS1
Green, M1
Reyes, J1
Nour, B1
Tzakis, A1
Todo, S1
Freitas, VR1
Fraser-Smith, EB1
Matthews, TR1
Wu, D1
Hockenberry, DM1
Brentnall, TA1
Baehr, PH1
Ponec, RJ1
Kuver, R1
Tzung, SP1
Todaro, JL1
McDonald, GB1
Jung, D1
AbdelHameed, MH1
Hunter, J1
Teitelbaum, P1
Dorr, A1
Griffy, K1
Asencio Marchante, R1
Lissen Otero, E1
Ryning, FW1
Mills, J1
Ehninger, G1
Vallbracht, A1
Schüch, K1
Kumbier, I1
Dopfer, R1
Schmidt, H1
Ostendorf, P1
Gardner, TD1
Youle, M1
Hanson, PJ1
Griffiths, PD1
Collins, JV1
Gazzard, BG1
Kim, CJ1
Pak, K1
Wakabayashi, Y1
Ishida, A1
Arai, Y1
Konishi, T1
Kounami, T1
Tomoyoshi, T1
Sako, H1
Okino, K1
Santiago-Delpín, EA1
Mora, E1
González, ZA1
Morales-Otero, LA1
Bermudez, R1
Santana, JL1
Ramírez-Ronda, CH1

Trials

2 trials available for trimethoprim and Cytomegalovirus Infections

ArticleYear
CMV pneumonia in HIV-infected ventilated infants.
    Pediatric pulmonology, 2010, Volume: 45, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Antiviral Agents; Cytomegalovirus Infectio

2010
The pharmacokinetics and safety profile of oral ganciclovir in combination with trimethoprim in HIV- and CMV-seropositive patients.
    British journal of clinical pharmacology, 1999, Volume: 47, Issue:3

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Cross-Over Studies; Cytomegalo

1999

Other Studies

15 other studies available for trimethoprim and Cytomegalovirus Infections

ArticleYear
Infectious diseases in renal allograft recipients: new developments in therapy and prevention.
    Transplantation proceedings, 1984, Volume: 16, Issue:4

    Topics: Acyclovir; Bacterial Infections; Cryptococcosis; Cytomegalovirus Infections; Drug Combinations; Huma

1984
Infectious complications of the acquired immune deficiency syndrome.
    Annals of the New York Academy of Sciences, 1984, Volume: 437

    Topics: Acquired Immunodeficiency Syndrome; Adult; Bacterial Infections; Cytomegalovirus Infections; Drug Co

1984
An outbreak of Pneumocystis carinii pneumonia in homosexual men.
    Annals of internal medicine, 1982, Volume: 96, Issue:6 Pt 1

    Topics: Adult; California; Candidiasis, Oral; Cytomegalovirus Infections; Disease Outbreaks; Drug Combinatio

1982
Pneumocystis carinii pneumonia in renal-transplant recipients treated with cyclosporine and steroids.
    The Journal of infectious diseases, 1984, Volume: 149, Issue:2

    Topics: Adolescent; Adult; Aged; Cyclosporins; Cytomegalovirus Infections; Drug Combinations; Female; Humans

1984
Pulmonary complications of the acquired immunodeficiency syndrome. Report of a National Heart, Lung, and Blood Institute workshop.
    The New England journal of medicine, 1984, Jun-21, Volume: 310, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Biopsy; Bronchoscopy; Cytomegalovirus Infections; Drug Combinati

1984
Early infectious complications of liver-intestinal transplantation in children: preliminary analysis.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Acyclovir; Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Cytomeg

1994
Efficacy of ganciclovir in combination with other antimicrobial agents against cytomegalovirus in vitro and in vivo.
    Antiviral research, 1993, Volume: 20, Issue:1

    Topics: Amphotericin B; Animals; Antifungal Agents; Antiviral Agents; Cells, Cultured; Cytomegalovirus Infec

1993
Persistent nausea and anorexia after marrow transplantation: a prospective study of 78 patients.
    Transplantation, 1998, Nov-27, Volume: 66, Issue:10

    Topics: Adolescent; Adult; Anorexia; Anti-Infective Agents; Bone Marrow Transplantation; Child; Child, Presc

1998
[Secondary prevention of opportunistic infections in HIV-infected patients].
    Revista clinica espanola, 2001, Volume: 201, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal A

2001
Pneumocystis carinii, Toxoplasma gondii, Cytomegalovirus and the compromised host.
    The Western journal of medicine, 1979, Volume: 130, Issue:1

    Topics: Adolescent; Adult; Animals; Cats; Child; Child, Preschool; Cytomegalovirus Infections; Female; Human

1979
[Oral prophylaxis of herpes infections using acyclovir following bone marrow transplantation: a clinical and clinico-pharmacological study].
    Klinische Wochenschrift, 1986, Jun-16, Volume: 64, Issue:12

    Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Presc

1986
Diagnosis, treatment and outcome of pneumonia in the acquired immune deficiency syndrome.
    The Journal of infection, 1989, Volume: 18, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Biopsy; Bronchoscopy; Cytomegalovirus Infections; Drug Combinati

1989
[Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:4

    Topics: Adult; Cyclosporins; Cytomegalovirus Infections; Humans; Kidney Failure, Chronic; Kidney Transplanta

1989
Factors in an outbreak of Pneumocystis carinii in a transplant unit.
    Transplantation proceedings, 1988, Volume: 20, Issue:1 Suppl 1

    Topics: Cross Infection; Cyclosporins; Cytomegalovirus Infections; Disease Outbreaks; Drug Combinations; Hum

1988
[The pregnant woman infected with the human immunodeficiency virus: recommendations for her management].
    Boletin de la Asociacion Medica de Puerto Rico, 1988, Volume: 80, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Cytomegalovirus Infections; Female; Humans; Ketocon

1988