trimethoprim has been researched along with Conjunctivitis, Bacterial in 9 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Conjunctivitis, Bacterial: Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A safety and efficacy study comparing the clinical and bacteriologic effectiveness of trimethoprim-sulfacetamide-polymyxin B-neomycin-gramicidin in a group of patients with surface ocular bacterial infections was conducted." | 9.05 | Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections. ( Austin, R; Knowlton, G; Nozik, RA; Smolin, G, 1985) |
| "A safety and efficacy study comparing the clinical and bacteriologic effectiveness of trimethoprim-sulfacetamide-polymyxin B-neomycin-gramicidin in a group of patients with surface ocular bacterial infections was conducted." | 5.05 | Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections. ( Austin, R; Knowlton, G; Nozik, RA; Smolin, G, 1985) |
| "Although evidence suggests that erythromycin at 50 mg/kg per day for 14 days results in higher numbers of cure than does azithromycin, compliance and risk of pyloric stenosis related to their use for other infections in neonates will factor into treatment recommendations." | 4.98 | Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis. ( Broutet, N; Lincetto, O; Santesso, N; Schünemann, H; Wi, T; Zikic, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zikic, A | 1 |
| Schünemann, H | 1 |
| Wi, T | 1 |
| Lincetto, O | 1 |
| Broutet, N | 1 |
| Santesso, N | 1 |
| Asbell, PA | 1 |
| DeCory, HH | 1 |
| Henao, MP | 1 |
| Ghaffari, G | 1 |
| Williams, L | 1 |
| Malhotra, Y | 1 |
| Murante, B | 1 |
| Laverty, S | 1 |
| Cook, S | 1 |
| Topa, D | 1 |
| Hardy, D | 1 |
| Wang, H | 1 |
| Gigliotti, F | 1 |
| Yolton, DP | 1 |
| Nozik, RA | 1 |
| Smolin, G | 1 |
| Knowlton, G | 1 |
| Austin, R | 1 |
| Lohr, JA | 1 |
| Austin, RD | 1 |
| Grossman, M | 1 |
| Hayden, GF | 1 |
| Knowlton, GM | 1 |
| Dudley, SM | 1 |
| Behrens-Baumann, W | 1 |
| Quentin, CD | 1 |
| Gibson, JR | 1 |
| Calthrop, JG | 1 |
| Harvey, SG | 1 |
| Booth, K | 1 |
2 reviews available for trimethoprim and Conjunctivitis, Bacterial
| Article | Year |
|---|---|
Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis.
Topics: Anti-Bacterial Agents; Azithromycin; Bias; Chlamydia Infections; Chlamydia trachomatis; Conjunctivit | 2018 |
New antibacterial drugs for topical ophthalmic use.
Topics: Ciprofloxacin; Conjunctivitis, Bacterial; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, | 1992 |
5 trials available for trimethoprim and Conjunctivitis, Bacterial
| Article | Year |
|---|---|
A single-blinded randomized clinical trial comparing polymyxin B-trimethoprim and moxifloxacin for treatment of acute conjunctivitis in children.
Topics: Adolescent; Anti-Bacterial Agents; Aza Compounds; Child; Child, Preschool; Conjunctiva; Conjunctivit | 2013 |
Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Blepharitis; Child; Conjunctivitis, Bacterial; Double | 1985 |
Trimethoprim-polymyxin B sulphate ophthalmic ointment versus chloramphenicol ophthalmic ointment in the treatment of bacterial conjunctivitis--a review of four clinical studies. The Trimethoprim-Polymyxin B Sulphate Ophthalmic Ointment Study Group.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chloramphenicol; Conjunctivitis, Bacterial; Humans | 1989 |
Comparison of three topical antimicrobials for acute bacterial conjunctivitis.
Topics: Administration, Topical; Adolescent; Adult; Child; Child, Preschool; Conjunctivitis, Bacterial; Drug | 1988 |
Trimethoprim-polymyxin B sulphate ophthalmic ointment in the treatment of bacterial conjunctivitis: a double-blind study versus chloramphenicol ophthalmic ointment.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chloramphenicol; Conjunctivitis, Bacterial; Double | 1988 |
2 other studies available for trimethoprim and Conjunctivitis, Bacterial
| Article | Year |
|---|---|
Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azithromycin; Child; | 2018 |
Anaphylaxis to polymyxin B-trimethoprim eye drops.
Topics: Anaphylaxis; Child, Preschool; Conjunctivitis, Bacterial; Drug Combinations; Drug Hypersensitivity; | 2016 |