trimethoprim has been researched along with Cell Transformation, Neoplastic in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cultures of Friend erythroleukemia cells were subjected to the antibiotics trimethoprim (T) and sulfamethoxazole (S) at levels equal to or below the usual therapeutic range." | 1.26 | The effect of trimethoprim/sulfamethoxazole on Friend erythroleukemia cells. ( Campbell, CL; Hillman, RS; Rabinovitch, PS; Steinberg, SE, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steinberg, SE | 1 |
| Campbell, CL | 1 |
| Rabinovitch, PS | 1 |
| Hillman, RS | 1 |
1 other study available for trimethoprim and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
The effect of trimethoprim/sulfamethoxazole on Friend erythroleukemia cells.
Topics: Cell Transformation, Neoplastic; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Erythrocyte | 1980 |