trimethoprim has been researched along with Canine Diseases in 45 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of a 9-year-old spayed female mixed-breed dog with trimethoprim-sulfadiazine for a prolonged period resulted in clinical signs of hypothyroidism, and results of thyroid gland function tests were indistinguishable from those associated with endogenous hypothyroidism." | 7.70 | Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog. ( Bunch, SE; Gookin, JL; Trepanier, LA, 1999) |
| "A diagnosis of trimethoprim/sulfadiazine-induced, immune-mediated thrombocytopenia in a dog was made, using a novel in vitro assay for thrombolytic activity." | 7.68 | Thrombocytopenia associated with administration of trimethoprim/sulfadiazine in a dog. ( Arrington, K; McDonald, TP; Sullivan, PS; West, R, 1992) |
| "In vitro susceptibility testing correctly predicted the outcome of ampicillin therapy in all 56 urinary tract infections (UTI) caused by coagulase-positive staphylococci (Staphylococcus aureus and S intermedius), in all 26 UTI caused by Proteus mirabilis, in 38 of 44 UTI caused by Escherichia coli, in 29 of 31 UTI caused by Streptococcus spp, in 8 of 10 UTI caused by Klebsiella pneumoniae, and in 16 of 20 UTI caused by other bacterial species." | 7.67 | Canine urinary tract infections: a comparison of in vitro antimicrobial susceptibility test results and response to oral therapy with ampicillin or with trimethoprim-sulfa. ( Jang, SS; Johnson, DL; Ling, GV; Rohrich, PJ; Ruby, AL, 1984) |
| "Efficacy of single-dose and 3-day trimethoprim-sulfadiazine (TMS) and amikacin treatment regimens for induced Escherichia coli urinary tract infections (UTI) in dogs was evaluated." | 7.67 | Effects of single-dose and three-day trimethoprim-sulfadiazine and amikacin treatment of induced Escherichia coli urinary tract infections in dogs. ( Lees, GE; Rogers, KS; Simpson, RB, 1988) |
| "Trimethoprim, in combination with sulfadiazine or sulfamethoxazole was administered orally for 7 to 14 days to 84 dogs with urinary tract infections (UTI)." | 7.66 | Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections. ( Ling, GV; Ruby, AL, 1979) |
| " Starting 2 days after infection was induced, group-II dogs were treated with trimethoprim-sulfadiazine at a dosage of 15 mg/kg given orally 2 times a day for 21 days; groups-III and -IV dogs were treated with single oral dosages of the antibiotic at 60 mg/kg and 90 mg/kg, respectively." | 5.27 | Comparison of single-dose and conventional trimethoprim-sulfadiazine therapy in experimental Staphylococcus intermedius cystitis in the female dog. ( Cox, HU; Gossett, KA; Kearney, MT; Roy, AF; Thomas, DE; Troy, GC; Turnwald, GH, 1986) |
| "Treatment of a 9-year-old spayed female mixed-breed dog with trimethoprim-sulfadiazine for a prolonged period resulted in clinical signs of hypothyroidism, and results of thyroid gland function tests were indistinguishable from those associated with endogenous hypothyroidism." | 3.70 | Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog. ( Bunch, SE; Gookin, JL; Trepanier, LA, 1999) |
| "A diagnosis of trimethoprim/sulfadiazine-induced, immune-mediated thrombocytopenia in a dog was made, using a novel in vitro assay for thrombolytic activity." | 3.68 | Thrombocytopenia associated with administration of trimethoprim/sulfadiazine in a dog. ( Arrington, K; McDonald, TP; Sullivan, PS; West, R, 1992) |
| "In vitro susceptibility testing correctly predicted the outcome of ampicillin therapy in all 56 urinary tract infections (UTI) caused by coagulase-positive staphylococci (Staphylococcus aureus and S intermedius), in all 26 UTI caused by Proteus mirabilis, in 38 of 44 UTI caused by Escherichia coli, in 29 of 31 UTI caused by Streptococcus spp, in 8 of 10 UTI caused by Klebsiella pneumoniae, and in 16 of 20 UTI caused by other bacterial species." | 3.67 | Canine urinary tract infections: a comparison of in vitro antimicrobial susceptibility test results and response to oral therapy with ampicillin or with trimethoprim-sulfa. ( Jang, SS; Johnson, DL; Ling, GV; Rohrich, PJ; Ruby, AL, 1984) |
| "Efficacy of single-dose and 3-day trimethoprim-sulfadiazine (TMS) and amikacin treatment regimens for induced Escherichia coli urinary tract infections (UTI) in dogs was evaluated." | 3.67 | Effects of single-dose and three-day trimethoprim-sulfadiazine and amikacin treatment of induced Escherichia coli urinary tract infections in dogs. ( Lees, GE; Rogers, KS; Simpson, RB, 1988) |
| "During a 4-year period, keratoconjunctivitis sicca developed in 14 dogs treated with sulfonamides (13, sulfasalazine; 1, sulfadiazine and trimethoprim)." | 3.66 | Keratoconjunctivitis sicca associated with sulfonamide therapy in dogs. ( Bachrach, A; Morgan, RV, 1982) |
| "Trimethoprim, in combination with sulfadiazine or sulfamethoxazole was administered orally for 7 to 14 days to 84 dogs with urinary tract infections (UTI)." | 3.66 | Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections. ( Ling, GV; Ruby, AL, 1979) |
| "Pyometra is a common infectious condition, especially in elderly bitches." | 3.30 | A double-blinded randomized placebo-controlled non-inferiority trial protocol for postoperative infections associated with canine pyometra. ( Grönthal, T; Junnila, J; Laitinen-Vapaavuori, O; Mölsä, S; Rantala, M; Thomson, K; Ylhäinen, A, 2023) |
| "Records of 8 dogs with drug-associated aplastic anemia were reviewed." | 1.28 | Drug-associated aplastic anemia in dogs: eight cases (1984-1988). ( Klausner, JS; Weiss, DJ, 1990) |
| " Starting 2 days after infection was induced, group-II dogs were treated with trimethoprim-sulfadiazine at a dosage of 15 mg/kg given orally 2 times a day for 21 days; groups-III and -IV dogs were treated with single oral dosages of the antibiotic at 60 mg/kg and 90 mg/kg, respectively." | 1.27 | Comparison of single-dose and conventional trimethoprim-sulfadiazine therapy in experimental Staphylococcus intermedius cystitis in the female dog. ( Cox, HU; Gossett, KA; Kearney, MT; Roy, AF; Thomas, DE; Troy, GC; Turnwald, GH, 1986) |
| "Treatment with sulfadiazine-trimethoprim caused serious, but reversible, allergic drug reactions in 6 Doberman Pinschers 10 to 21 days after the first drug exposure and/or within 1 hour to 10 days after reexposure." | 1.27 | Sulfadiazine-induced allergy in six Doberman pinschers. ( Giger, U; Gorman, NT; Millichamp, NJ; Werner, LL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (46.67) | 18.7374 |
| 1990's | 15 (33.33) | 18.2507 |
| 2000's | 4 (8.89) | 29.6817 |
| 2010's | 3 (6.67) | 24.3611 |
| 2020's | 2 (4.44) | 2.80 |
| Authors | Studies |
|---|---|
| Ylhäinen, A | 1 |
| Mölsä, S | 1 |
| Grönthal, T | 1 |
| Junnila, J | 1 |
| Rantala, M | 1 |
| Laitinen-Vapaavuori, O | 1 |
| Thomson, K | 1 |
| Birckhead, A | 1 |
| Combs, M | 1 |
| Croser, E | 1 |
| Montgomery, A | 1 |
| Peters, A | 1 |
| Stark, D | 1 |
| Malik, R | 2 |
| Best, MP | 1 |
| Boyd, SP | 1 |
| Danesi, P | 1 |
| Worthing, KA | 1 |
| Norris, JM | 1 |
| Briscoe, KA | 1 |
| Prandini da Costa Reis, R | 1 |
| Crisman, R | 1 |
| Roser, M | 1 |
| Šlapeta, J | 1 |
| Vincent-Johnson, N | 1 |
| Morgan, RV | 1 |
| Bachrach, A | 1 |
| Johnson, CA | 1 |
| Bennett, M | 1 |
| Jensen, RK | 1 |
| Schirmer, R | 1 |
| Ling, GV | 3 |
| Rohrich, PJ | 1 |
| Ruby, AL | 2 |
| Johnson, DL | 1 |
| Jang, SS | 1 |
| Anderson, WI | 1 |
| Campbell, KL | 1 |
| Wilson, RC | 1 |
| Goetsch, DD | 1 |
| Toth, DM | 1 |
| Derwelis, SK | 1 |
| Sigel, CW | 1 |
| Macklin, AW | 1 |
| Grace, ME | 1 |
| Tracy, CH | 1 |
| Hinton, M | 1 |
| Marston, M | 1 |
| Crisfield, J | 1 |
| Powers, TE | 1 |
| Powers, JD | 1 |
| Garg, RC | 1 |
| Scialli, VT | 1 |
| Hajian, GH | 1 |
| Rohner, K | 1 |
| Demuth, D | 1 |
| Dodds, WJ | 1 |
| Schrauwen, E | 1 |
| Bunch, SE | 2 |
| Noli, C | 1 |
| Koeman, JP | 1 |
| Willemse, T | 1 |
| Pellerin, JL | 1 |
| Bourdeau, P | 1 |
| Sebbag, H | 1 |
| Person, JM | 1 |
| Gookin, JL | 1 |
| Trepanier, LA | 1 |
| Speakman, AJ | 1 |
| Dawson, S | 1 |
| Corkill, JE | 1 |
| Binns, SH | 1 |
| Hart, CA | 1 |
| Gaskell, RM | 1 |
| Pelle, G | 1 |
| Makrai, L | 1 |
| Fodor, L | 1 |
| Dobos-Kovács, M | 1 |
| Macintire, DK | 1 |
| Vincent-Johnson, NA | 1 |
| Kane, CW | 1 |
| Lindsay, DS | 2 |
| Blagburn, BL | 1 |
| Dillon, AR | 1 |
| McCandlish, IA | 1 |
| Thompson, H | 1 |
| Cannon, RW | 1 |
| Sullivan, PS | 1 |
| Arrington, K | 1 |
| West, R | 1 |
| McDonald, TP | 1 |
| McNeil, PE | 1 |
| Busch, DS | 1 |
| Noxon, JO | 1 |
| Rowland, PH | 1 |
| Center, SA | 1 |
| Dougherty, SA | 1 |
| Little, CJ | 1 |
| Carmichael, S | 1 |
| Gray, A | 1 |
| Weiss, DJ | 2 |
| Klausner, JS | 1 |
| Hay, WH | 1 |
| Shell, LG | 1 |
| Dubey, JP | 1 |
| Rogers, KS | 1 |
| Lees, GE | 1 |
| Simpson, RB | 1 |
| Sutton, DJ | 1 |
| Roach, NJ | 1 |
| Collins, BK | 1 |
| Moore, CP | 1 |
| Hagee, JH | 1 |
| Whur, P | 1 |
| Harvey, RG | 1 |
| Adams, LG | 1 |
| Turnwald, GH | 1 |
| Gossett, KA | 1 |
| Cox, HU | 1 |
| Kearney, MT | 1 |
| Roy, AF | 1 |
| Thomas, DE | 1 |
| Troy, GC | 1 |
| Giger, U | 1 |
| Werner, LL | 1 |
| Millichamp, NJ | 1 |
| Gorman, NT | 1 |
| Craig, GR | 1 |
2 reviews available for trimethoprim and Canine Diseases
| Article | Year |
|---|---|
Treatment of urinary tract infections.
Topics: Ampicillin; Animals; Dog Diseases; Dogs; Escherichia coli Infections; Penicillin G; Penicillin Resis | 1980 |
Hepatotoxicity associated with pharmacologic agents in dogs and cats.
Topics: Animals; Anthelmintics; Benzimidazoles; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; | 1993 |
1 trial available for trimethoprim and Canine Diseases
| Article | Year |
|---|---|
A double-blinded randomized placebo-controlled non-inferiority trial protocol for postoperative infections associated with canine pyometra.
Topics: Animals; Bacterial Infections; Bacteriuria; Clinical Trials, Veterinary as Topic; Dog Diseases; Dogs | 2023 |
42 other studies available for trimethoprim and Canine Diseases
| Article | Year |
|---|---|
Presumptive neural microsporidiosis in a young adult German Shepherd dog from rural Australia.
Topics: Animals; Australia; Dog Diseases; Dogs; Male; Microsporidiosis; Trimethoprim | 2021 |
Confirmed case of Pneumocystis pneumonia in a Maltese Terrier × Papillon dog being treated with toceranib phosphate.
Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Female; Indoles; Mast-Cell Sarcoma; Pneumonia, Pneum | 2019 |
Severe acute cellulitis and sepsis caused by Aeromonas spp. in a dog on immunosuppressive therapy.
Topics: Aeromonas; Animals; Anti-Bacterial Agents; Cellulitis; Dog Diseases; Dogs; Drug Combinations; Female | 2019 |
Neonatal neosporosis in a 2-week-old Bernese mountain dog infected with multiple Neospora caninum strains based on MS10 microsatellite analysis.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Clindamycin; Coccidiosis; Dog Diseases; Dogs; | 2016 |
Questions limitation in treatment of hepatozoonosis.
Topics: Animals; Clindamycin; Coccidiosis; Coccidiostats; Decoquinate; Dog Diseases; Dogs; Drug Combinations | 2005 |
Keratoconjunctivitis sicca associated with sulfonamide therapy in dogs.
Topics: Animals; Dog Diseases; Dogs; Female; Keratoconjunctivitis; Male; Sulfadiazine; Sulfasalazine; Sulfon | 1982 |
Effect of combined antibiotic therapy on fertility in brood bitches infected with Brucella canis.
Topics: Abortion, Septic; Abortion, Veterinary; Animals; Brucellosis; Dihydrostreptomycin Sulfate; Dog Disea | 1982 |
Canine urinary tract infections: a comparison of in vitro antimicrobial susceptibility test results and response to oral therapy with ampicillin or with trimethoprim-sulfa.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacteria; Bacterial Infe | 1984 |
Hepatitis in a dog given sulfadiazine-trimethoprim and cyclophosphamide.
Topics: Animals; Anti-Infective Agents, Urinary; Chemical and Drug Induced Liver Injury; Cyclophosphamide; D | 1984 |
Drug-induced hepatitis in a dog: a case report.
Topics: Animals; Cystitis; Dog Diseases; Dogs; Female; Hepatitis, Animal; Prednisone; Sulfonamides; Trimetho | 1980 |
Trimethoprim and sulfadiazine concentrations in aqueous and vitreous humors of the dog.
Topics: Animals; Aqueous Humor; Dog Diseases; Dogs; Endophthalmitis; Female; Male; Sulfadiazine; Trimethopri | 1981 |
The in vitro resistance of canine staphylococci to trimethoprim and sulphamethoxazole alone and in combination.
Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug Resistance, Microbial; Microbial Sensitivity Te | 1981 |
Trimethoprim and sulfadiazine: experimental infection of Beagles.
Topics: Animals; Blood; Dog Diseases; Dogs; Drug Combinations; Female; Injections, Subcutaneous; Male; Strep | 1980 |
[Adverse effects of veterinary drugs].
Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dipyrone; Dog Diseases; Dogs; Drug Combinations; | 1994 |
Hemorrhagic complications attributable to certain drugs.
Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Combinations; Hemorrhage; Sulfonamides; Thromb | 1993 |
Canine dysautonomia: another case report.
Topics: Animals; Autonomic Nervous System Diseases; Bone Neoplasms; Cisplatin; Dog Diseases; Dogs; Drug Comb | 1993 |
A retrospective evaluation of adverse reactions to trimethoprim-sulphonamide combinations in dogs and cats.
Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Combinations; Drug Erup | 1995 |
Epidemiosurveillance of antimicrobial compound resistance of Staphylococcus intermedium clinical isolates from canine pyodermas.
Topics: Aminoglycosides; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Ceph | 1998 |
Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog.
Topics: Animals; Anti-Infective Agents, Urinary; Dog Diseases; Dogs; Drug Combinations; Female; Hypothyroidi | 1999 |
Antibiotic susceptibility of canine Bordetella bronchiseptica isolates.
Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infe | 2000 |
Actinomycosis of dogs caused by Actinomyces hordeovulneris.
Topics: Actinomyces; Actinomycosis; Amoxicillin; Animals; Anti-Infective Agents; Dog Diseases; Dogs; Drug Th | 2000 |
Treatment of dogs infected with Hepatozoon americanum: 53 cases (1989-1998).
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antiprotozoal | 2001 |
Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections.
Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Escherichia coli Infec | 1979 |
Canine bordetellosis: chemotherapy using a sulphadiazine-trimethoprim combination.
Topics: Animals; Bordetella Infections; Bronchi; Dog Diseases; Dogs; Drug Therapy, Combination; Sulfadiazine | 1979 |
Clinical evaluation of Tribrissen. New antibacterial agent for dogs and cats.
Topics: Animals; Bacterial Infections; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Combinations; Sulfadiazi | 1976 |
Thrombocytopenia associated with administration of trimethoprim/sulfadiazine in a dog.
Topics: Animals; Anti-Infective Agents; Blood Platelets; Dog Diseases; Dogs; Drug Combinations; Epistaxis; F | 1992 |
Acute tubulo-interstitial nephritis in a dog after halothane anaesthesia and administration of flunixin meglumine and trimethoprim-sulphadiazine.
Topics: Anesthesia, Inhalation; Animals; Anti-Infective Agents, Urinary; Clonixin; Dog Diseases; Dogs; Drug | 1992 |
Pneumothorax in a dog infected with Dirofilaria immitis.
Topics: Animals; Chemotherapy, Adjuvant; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Drug Combi | 1992 |
Presumptive trimethoprim-sulfadiazine-related hepatotoxicosis in a dog.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dog Diseases; Dogs; Drug Combinations; Follow-Up St | 1992 |
Trimethoprim-sulphonamide hypersensitivity in dogs.
Topics: Animals; Dog Diseases; Dogs; Drug Hypersensitivity; Joint Diseases; Male; Sulfonamides; Trimethoprim | 1990 |
Trimethoprim-sulphonamide hypersensitivity in dogs.
Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug Hypersensitivity; Female; Male; Sulfonamides; T | 1990 |
Drug-associated aplastic anemia in dogs: eight cases (1984-1988).
Topics: Anemia, Aplastic; Animals; Anti-Infective Agents; Antimalarials; Dog Diseases; Dogs; Drug Combinatio | 1990 |
Diagnosis and treatment of Neospora caninum infection in a dog.
Topics: Animals; Antibodies, Protozoan; Biopsy; Clindamycin; Dog Diseases; Dogs; Drug Therapy, Combination; | 1990 |
Effects of single-dose and three-day trimethoprim-sulfadiazine and amikacin treatment of induced Escherichia coli urinary tract infections in dogs.
Topics: Amikacin; Animals; Anti-Infective Agents, Urinary; Bacteriuria; Dog Diseases; Dogs; Drug Administrat | 1988 |
Keratoconjunctivitis sicca associated with potentiated sulphonamides.
Topics: Animals; Anti-Infective Agents; Dog Diseases; Dogs; Drug Combinations; Keratoconjunctivitis; Keratoc | 1988 |
Sulfonamide-associated keratoconjunctivitis sicca and corneal ulceration in a dysuric dog.
Topics: Animals; Corneal Ulcer; Dog Diseases; Dogs; Drug Combinations; Keratoconjunctivitis; Keratoconjuncti | 1986 |
Possible trimethoprim-sulphonamide induced polyarthritis.
Topics: Animals; Anti-Infective Agents; Arthritis; Dog Diseases; Dogs; Drug Combinations; Female; Pyoderma; | 1987 |
Possible sulphadiazine-trimethoprim induced polyarthritis.
Topics: Animals; Anti-Infective Agents, Urinary; Arthritis; Dog Diseases; Dogs; Drug Combinations; Female; M | 1987 |
Aplastic anemia associated with trimethoprim-sulfadiazine and fenbendazole administration in a dog.
Topics: Anemia, Aplastic; Animals; Anti-Infective Agents; Benzimidazoles; Bronchiectasis; Bronchitis; Dog Di | 1987 |
Comparison of single-dose and conventional trimethoprim-sulfadiazine therapy in experimental Staphylococcus intermedius cystitis in the female dog.
Topics: Administration, Oral; Animals; Cystitis; Dog Diseases; Dogs; Drug Administration Schedule; Drug Comb | 1986 |
Sulfadiazine-induced allergy in six Doberman pinschers.
Topics: Animals; Arthritis; Dog Diseases; Dogs; Drug Hypersensitivity; Drug Therapy, Combination; Glomerulon | 1985 |
The place of potentiated trimethoprim in the therapy of diseases of the skin in dogs and cats.
Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Folic Acid Antagonists; Pyri | 1972 |