trimethoprim has been researched along with Burkholderia pseudomallei Infection in 16 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethoprim-sulfamethoxazole (co-trimoxazole) is the primary drug used for oral eradication therapy of Burkholderia pseudomallei infections (melioidosis)." | 3.79 | The BpeEF-OprC efflux pump is responsible for widespread trimethoprim resistance in clinical and environmental Burkholderia pseudomallei isolates. ( Peacock, SJ; Podnecky, NL; Schweizer, HP; Wuthiekanun, V, 2013) |
| "Treatment for melioidosis is unaffordable for many in endemic areas of the developing world, but the relative costs have reduced over the past decade." | 2.50 | Treatment and prophylaxis of melioidosis. ( Dance, D, 2014) |
| "We describe 58 adult patients with melioidosis in Cambodia (2007-2010)." | 1.37 | Melioidosis, phnom penh, Cambodia. ( De Smet, B; Jacobs, J; Kham, C; Koole, O; Kruy, L; Lynen, L; Phe, T; Thai, S; Veng, CH; Vlieghe, E, 2011) |
| " A pharmacokinetic (PK) simulation study was performed to determine the optimal dosing of cotrimoxazole (trimethoprim-sulfamethoxazole [TMP-SMX]) used in current eradication regimens in Thailand and Australia." | 1.35 | Dosing regimens of cotrimoxazole (trimethoprim-sulfamethoxazole) for melioidosis. ( Amornchai, P; Cheng, AC; Chierakul, W; Day, NP; McBryde, ES; Peacock, SJ; White, NJ; Wuthiekanun, V, 2009) |
| "The first case of melioidosis diagnosed in New Zealand is described." | 1.27 | Melioidosis: a new disease to New Zealand. ( Corkill, MM; Cornere, B, 1987) |
| "Previous reports of melioidosis in Sabah are reviewed and a detailed account of a case, presenting as prostatitis, in a 40-year-old British male is given." | 1.26 | Melioidosis presenting as prostatitis--a case report from Sabah. ( Kan, SK; Kay, RW, 1978) |
| "When treated with trimethoprim-sulfamethoxazole, there was prompt resolution of his symptoms and the left upper lobe abscess cavity." | 1.26 | Trimethoprim-sulfamethoxazole therapy of pulmonary melioidosis. ( John, JF, 1976) |
| "An instance of melioidosis is described in a five-year-old Papua New Guinean." | 1.25 | Melioidosis in a child in papua new guinea successful treatment with kanamycin and trimethoprim-sulphamethoxazole. ( De Buse, PJ; Henderson, A; White, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bugrysheva, JV | 1 |
| Sue, D | 1 |
| Gee, JE | 1 |
| Elrod, MG | 1 |
| Hoffmaster, AR | 1 |
| Randall, LB | 1 |
| Chirakul, S | 2 |
| Tuanyok, A | 1 |
| Schweizer, HP | 3 |
| Weigel, LM | 1 |
| Jun, JB | 1 |
| Lee, T | 1 |
| Jeong, J | 1 |
| Chun, JH | 1 |
| Shin, YW | 1 |
| Jung, J | 1 |
| Podnecky, NL | 2 |
| Rhodes, KA | 1 |
| Mima, T | 1 |
| Drew, HR | 1 |
| Wuthiekanun, V | 4 |
| Schupp, JM | 1 |
| Sarovich, DS | 1 |
| Currie, BJ | 1 |
| Keim, P | 1 |
| Young, A | 1 |
| Tacon, C | 1 |
| Smith, S | 1 |
| Reeves, B | 1 |
| Wiseman, G | 1 |
| Hanson, J | 1 |
| Peacock, SJ | 2 |
| Dance, D | 1 |
| Cheng, AC | 1 |
| McBryde, ES | 1 |
| Chierakul, W | 1 |
| Amornchai, P | 1 |
| Day, NP | 1 |
| White, NJ | 2 |
| Vlieghe, E | 1 |
| Kruy, L | 1 |
| De Smet, B | 1 |
| Kham, C | 1 |
| Veng, CH | 1 |
| Phe, T | 1 |
| Koole, O | 1 |
| Thai, S | 1 |
| Lynen, L | 1 |
| Jacobs, J | 1 |
| Fuller, PB | 1 |
| Fisk, DE | 1 |
| Byrd, RB | 1 |
| Griggs, GA | 1 |
| Smith, MR | 1 |
| Kan, SK | 1 |
| Kay, RW | 1 |
| Morrison, RE | 1 |
| Young, EJ | 1 |
| Harper, WK | 1 |
| Maldonado, L | 1 |
| John, JF | 1 |
| De Buse, PJ | 1 |
| Henderson, A | 1 |
| White, M | 1 |
| Dance, DA | 1 |
| Chaowagul, W | 1 |
| Wattanagoon, Y | 1 |
| Pitakwatchara, N | 1 |
| Germain, M | 1 |
| Auger, F | 1 |
| Murray, G | 1 |
| Corkill, MM | 1 |
| Cornere, B | 1 |
1 review available for trimethoprim and Burkholderia pseudomallei Infection
| Article | Year |
|---|---|
Treatment and prophylaxis of melioidosis.
Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Burkhold | 2014 |
1 trial available for trimethoprim and Burkholderia pseudomallei Infection
| Article | Year |
|---|---|
Halving of mortality of severe melioidosis by ceftazidime.
Topics: Actuarial Analysis; Administration, Oral; Adolescent; Adult; Aged; Ceftazidime; Child; Chloramphenic | 1989 |
14 other studies available for trimethoprim and Burkholderia pseudomallei Infection
| Article | Year |
|---|---|
Antibiotic Resistance Markers in Burkholderia pseudomallei Strain Bp1651 Identified by Genome Sequence Analysis.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Burkholderia | 2017 |
Accidental Occupational Exposure to Burkholderia pseudomallei in South Korea Did Not Result in Melioidosis.
Topics: Burkholderia pseudomallei; Cross Infection; Drug Combinations; Humans; Male; Melioidosis; Middle Age | 2017 |
Mechanisms of Resistance to Folate Pathway Inhibitors in
Topics: Anti-Bacterial Agents; Burkholderia pseudomallei; Drug Resistance, Multiple, Bacterial; Folic Acid; | 2017 |
Case Report: Fatal Pediatric Melioidosis Despite Optimal Intensive Care.
Topics: Anti-Bacterial Agents; Australia; Burkholderia pseudomallei; Child; Fatal Outcome; Humans; Intensive | 2017 |
The BpeEF-OprC efflux pump is responsible for widespread trimethoprim resistance in clinical and environmental Burkholderia pseudomallei isolates.
Topics: Anti-Bacterial Agents; Australia; Bacterial Proteins; Base Sequence; Burkholderia pseudomallei; Gene | 2013 |
Dosing regimens of cotrimoxazole (trimethoprim-sulfamethoxazole) for melioidosis.
Topics: Anti-Infective Agents; Burkholderia pseudomallei; Melioidosis; Microbial Sensitivity Tests; Models, | 2009 |
Melioidosis, phnom penh, Cambodia.
Topics: Adolescent; Adult; Aged; Burkholderia pseudomallei; Cambodia; Carbapenems; Cephalosporins; Diabetes | 2011 |
Treatment of pulmonary melioidosis with combination of trimethoprim and sulfamethoxazole.
Topics: Adult; Asia, Southeastern; Drug Combinations; Humans; Lung Diseases; Male; Melioidosis; Philippines; | 1978 |
Melioidosis presenting as prostatitis--a case report from Sabah.
Topics: Adult; Ampicillin; Drug Combinations; Gentamicins; Humans; Infertility, Male; Male; Melioidosis; Min | 1978 |
Chronic prostatic melioidosis treated with trimethoprim-sulfamethoxazole.
Topics: Adult; Antibodies, Bacterial; Chronic Disease; Humans; Male; Melioidosis; Prostatic Diseases; Pseudo | 1979 |
Trimethoprim-sulfamethoxazole therapy of pulmonary melioidosis.
Topics: Adult; Bacteriological Techniques; Dose-Response Relationship, Drug; Drug Therapy, Combination; Huma | 1976 |
Melioidosis in a child in papua new guinea successful treatment with kanamycin and trimethoprim-sulphamethoxazole.
Topics: Child, Preschool; Humans; Kanamycin; Male; Melioidosis; New Guinea; Sulfamethoxazole; Trimethoprim | 1975 |
Melioidosis in a traveller--Quebec.
Topics: Adult; Anti-Infective Agents; Drug Combinations; Humans; Lung Diseases; Male; Melioidosis; Quebec; S | 1989 |
Melioidosis: a new disease to New Zealand.
Topics: Administration, Oral; Adult; Drug Combinations; Humans; Liver Abscess; Male; Melioidosis; New Zealan | 1987 |