trimethoprim has been researched along with Brain Diseases in 7 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A mouse model of cerebral nocardiosis was used to determine relative antibiotic efficacy by reducing bacterial colony counts per gram of brain tissue." | 5.27 | Therapy of experimental cerebral nocardiosis with imipenem, amikacin, trimethoprim-sulfamethoxazole, and minocycline. ( Aulicino, TM; duBouchet, L; Gombert, ME; Sheinbaum, WM; Silverman, GE, 1986) |
| "A mouse model of cerebral nocardiosis was used to determine the efficacy of synergistic antimicrobial combinations in reducing bacterial colony counts per gram of brain tissue." | 1.28 | Antimicrobial synergism in the therapy of experimental cerebral nocardiosis. ( Aulicino, TM; Berkowitz, LB; duBouchet, L; Gombert, ME, 1989) |
| "A patient with a large paracoccidioidal granuloma in the right fronto-parietal region was treated with sulfamethoxazole-trimethoprim alone, without the use of amphotericin B or any surgical measures." | 1.27 | A new treatment for large cerebral paracoccidioidomycosis. ( Branchini, ML; Chuluc, SS; Guerreiro, CA, 1987) |
| "A mouse model of cerebral nocardiosis was used to determine relative antibiotic efficacy by reducing bacterial colony counts per gram of brain tissue." | 1.27 | Therapy of experimental cerebral nocardiosis with imipenem, amikacin, trimethoprim-sulfamethoxazole, and minocycline. ( Aulicino, TM; duBouchet, L; Gombert, ME; Sheinbaum, WM; Silverman, GE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piper, KJ | 1 |
| Foster, H | 1 |
| Susanto, D | 1 |
| Maree, CL | 1 |
| Thornton, SD | 1 |
| Cobbs, CS | 1 |
| Güven, MB | 1 |
| Cirak, B | 1 |
| Kutluhan, A | 1 |
| Ugras, S | 1 |
| Saül, A | 1 |
| Lavalle, P | 1 |
| Serrano, A | 1 |
| Zenteno, J | 1 |
| Hunziker, UA | 1 |
| Nadal, D | 1 |
| Jendis, JB | 1 |
| Tomasik, Z | 1 |
| Wetzel, JC | 1 |
| Schüpbach, J | 1 |
| Seger, RA | 1 |
| Gombert, ME | 2 |
| duBouchet, L | 2 |
| Aulicino, TM | 2 |
| Berkowitz, LB | 1 |
| Guerreiro, CA | 1 |
| Chuluc, SS | 1 |
| Branchini, ML | 1 |
| Silverman, GE | 1 |
| Sheinbaum, WM | 1 |
7 other studies available for trimethoprim and Brain Diseases
| Article | Year |
|---|---|
Fatal Balamuthia mandrillaris brain infection associated with improper nasal lavage.
Topics: Aged; Balamuthia mandrillaris; Brain; Brain Diseases; Exanthema; Fatal Outcome; Female; Humans; Nasa | 2018 |
Pituitary abscess secondary to neurobrucellosis. Case illustration.
Topics: Abscess; Adult; Anti-Infective Agents; Brain Diseases; Brucellosis; Drug Therapy, Combination; Endos | 1999 |
[Cephalic mycetoma, caused by Streptomyces somaliensis, involving the cranial cavity].
Topics: Adult; Brain Diseases; Diagnosis, Differential; Exophthalmos; Humans; Male; Mycetoma; Streptomyces; | 1975 |
Stable human immunodeficiency virus encephalopathy in two infants receiving early intravenous gammaglobulin plus antimicrobial prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Drug Combinations; Drug Therapy, Combination; HI | 1989 |
Antimicrobial synergism in the therapy of experimental cerebral nocardiosis.
Topics: Animals; Brain Diseases; Cefotaxime; Colony Count, Microbial; Drug Combinations; Drug Synergism; Dru | 1989 |
A new treatment for large cerebral paracoccidioidomycosis.
Topics: Brain Diseases; Drug Therapy, Combination; Humans; Male; Middle Aged; Paracoccidioidomycosis; Sulfam | 1987 |
Therapy of experimental cerebral nocardiosis with imipenem, amikacin, trimethoprim-sulfamethoxazole, and minocycline.
Topics: Amikacin; Animals; Brain Diseases; Drug Combinations; Female; Imipenem; Kinetics; Mice; Minocycline; | 1986 |