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trimethoprim and Brain Abscess

trimethoprim has been researched along with Brain Abscess in 16 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Brain Abscess: A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6)

Research Excerpts

ExcerptRelevanceReference
" We present a 49 year old woman with systemic lupus erythematosus and neuromyelitis optica spectrum disorder who was treated with mycophenolate mofetil, prednisone and recent plasmapheresis."4.02Disseminated nocardiosis in an immunosuppressed patient with systemic lupus erythematosus and neuromyelitis optica spectrum disorder. ( Chaudhry, ZA; Ginzler, E; Sharif, S; Terebelo, S, 2021)
" Antimicrobial treatment-related side effects require close monitoring, and dosage changes or therapy adjustments may be necessary."1.46First reported case of disseminated Nocardia kroppenstedtii sp nov. infection presenting with brain abscess and endocarditis in an immunocompromised patient with mantle cell lymphoma: challenges in diagnosis and treatment. ( Abdullah, HM; Al Mohajer, M; Majeed, A; Ullah, W, 2017)
"Tension pneumocephalus should be included in the differential diagnosis of nontraumatic hemiparesis for emergent evaluation and management."1.46Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma. ( Fernandez, J; Nanjappa, S; Pabbathi, S; Srikumar, T, 2017)
"We report 1 case of disseminated nocardiosis with pulmonary involvement, brain lesions, and bone lesions in a renal transplant patient, who was treated with stereotactic aspiration in association with high dose of trimethoprim/sulfamethoxazole (TMP/SMX) and imipenem, changed, after 3 weeks to moxifloxacin."1.33Intracranial Nocardia recurrence during fluorinated quinolones therapy. ( Dahan, K; Delahousse, M; El Kabbaj, D; Pastural, M; Venditto, M, 2006)
"Therapy in 19 consecutive cases of cerebral abscess was limited to medical treatment whenever possible, using high doses of a combination of several antibiotics."1.27[Primacy of medical treatment of cerebral abscesses (19 cases)]. ( Clarisse, J; Destée, A; Lesoin, F; Petit, H; Rousseaux, M; Warot, P, 1983)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199010 (62.50)18.7374
1990's0 (0.00)18.2507
2000's2 (12.50)29.6817
2010's2 (12.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Balachandar, A1
Zhabokritsky, A1
Matukas, LM1
Terebelo, S1
Sharif, S1
Chaudhry, ZA1
Ginzler, E1
Majeed, A1
Abdullah, HM1
Ullah, W1
Al Mohajer, M1
Srikumar, T1
Pabbathi, S1
Fernandez, J1
Nanjappa, S1
Dahan, K1
El Kabbaj, D1
Venditto, M1
Pastural, M1
Delahousse, M1
Khan, SH1
Sanche, SE1
Robinson, CA1
Pirouzmand, F1
Bertoldi, RV1
Sperling, MR1
Petit, H1
Rousseaux, M1
Lesoin, F1
Destée, A1
Clarisse, J1
Warot, P1
Takagi, T1
Nagai, H1
Kobayashi, M1
Shinagawa, N1
Greene, BM1
Thomas, FE1
Alford, RH1
Antonow, DR1
Yamaguchi, Y1
Miyake, H1
Nakahara, N1
Masuzawa, T1
Spehn, J1
Grosser, S1
Jessel, A1
von Essen, J1
Klose, G1
Klinger, M1
Fernández-Guerrero, ML1
Torres, A1
Díaz Curiel, M1
Soriano, F1
Maderazo, EG1
Quintiliani, R1

Reviews

1 review available for trimethoprim and Brain Abscess

ArticleYear
[Nocardial brain abscess: case report].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Brain Abscess; Combined Modality Therapy; Drug Combinations; Humans; M

1989

Other Studies

15 other studies available for trimethoprim and Brain Abscess

ArticleYear
Disseminated nocardiosis with multisite involvement in an immunocompetent patient.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2020, Aug-17, Volume: 192, Issue:33

    Topics: Aged; Anti-Infective Agents; Brain Abscess; Humans; Immunocompetence; Lung Diseases; Male; Nocardia

2020
Disseminated nocardiosis in an immunosuppressed patient with systemic lupus erythematosus and neuromyelitis optica spectrum disorder.
    Lupus, 2021, Volume: 30, Issue:2

    Topics: Brain Abscess; Female; Humans; Imipenem; Immunocompromised Host; Lung Abscess; Lupus Erythematosus,

2021
First reported case of disseminated Nocardia kroppenstedtii sp nov. infection presenting with brain abscess and endocarditis in an immunocompromised patient with mantle cell lymphoma: challenges in diagnosis and treatment.
    BMJ case reports, 2017, Jan-06, Volume: 2017

    Topics: Aged; Anti-Infective Agents; Brain Abscess; Diagnosis, Differential; Drug Combinations; Echocardiogr

2017
Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma.
    The American journal of case reports, 2017, Jan-10, Volume: 18

    Topics: Aged; Anti-Bacterial Agents; Aspergillosis; Aspergillus; Bacteremia; Brain Abscess; Cefepime; Cephal

2017
Intracranial Nocardia recurrence during fluorinated quinolones therapy.
    Transplant infectious disease : an official journal of the Transplantation Society, 2006, Volume: 8, Issue:3

    Topics: Amikacin; Aza Compounds; Brain Abscess; Drug Combinations; Fluoroquinolones; Humans; Imipenem; Kidne

2006
N. paucivorans infection presenting as a brain abscess.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2006, Volume: 33, Issue:4

    Topics: Anti-Bacterial Agents; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Humans; Hypertension

2006
Nocardia brain stem abscess: diagnosis and response to medical therapy.
    Bulletin of clinical neurosciences, 1984, Volume: 49

    Topics: Brain Abscess; Cefotaxime; Drug Therapy, Combination; Humans; Male; Middle Aged; Nocardia Infections

1984
[Primacy of medical treatment of cerebral abscesses (19 cases)].
    Revue neurologique, 1983, Volume: 139, Issue:10

    Topics: Adolescent; Adult; Aminoglycosides; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Brain

1983
[Pseudomonas cepacia meningitis: report of 3 cases].
    No shinkei geka. Neurological surgery, 1982, Volume: 10, Issue:1

    Topics: Adolescent; Brain Abscess; Cerebrospinal Fluid Shunts; Drug Therapy, Combination; Female; Humans; Hy

1982
Letter: Trimethoprim-sulfamethoxazole and brain abscess.
    Annals of internal medicine, 1975, Volume: 82, Issue:6

    Topics: Adult; Brain Abscess; Drug Combinations; Humans; Male; Mastoiditis; Sulfamethoxazole; Trimethoprim

1975
Acute pancreatitis associated with trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1986, Volume: 104, Issue:3

    Topics: Acute Disease; Adult; Amylases; Brain Abscess; Drug Combinations; Humans; Male; Nocardia asteroides;

1986
[High-dosage cotrimoxazole therapy of disseminated Nocardia brasiliensis infection].
    Deutsche medizinische Wochenschrift (1946), 1986, Feb-07, Volume: 111, Issue:6

    Topics: Brain Abscess; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Genta

1986
[Cerebrospinal fluid, brain and abscess permeability of antibiotics].
    Der Nervenarzt, 1986, Volume: 57, Issue:10

    Topics: Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Brain Abscess; Cefurox

1986
Successful treatment of nocardial thigh abscess and possible brain abscess with co-trimoxazole.
    European journal of clinical microbiology, 1985, Volume: 4, Issue:4

    Topics: Abscess; Brain Abscess; Drug Combinations; Humans; Male; Middle Aged; Nocardia asteroides; Nocardia

1985
Treatment of nocardial infection with trimethoprim and sulfamethoxazole.
    The American journal of medicine, 1974, Volume: 57, Issue:4

    Topics: Administration, Oral; Adult; Ampicillin; Brain Abscess; Humans; Lung; Lung Diseases; Male; Nocardia

1974