trimethoprim has been researched along with Bone Marrow Diseases in 4 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Bone Marrow Diseases: Diseases involving the BONE MARROW.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 61-year-old patient with rheumatoid arthritis receiving treatment with methotrexate developed bone marrow hypoplasia after treatment with trimethoprim-sulfamethoxazole." | 3.67 | Methotrexate toxicity in a patient receiving trimethoprim-sulfamethoxazole. ( Gutterman, LA; Thomas, MH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Collins, IS | 1 |
| Blackwell, EA | 1 |
| Hawson, GA | 1 |
| Leer, J | 1 |
| Bain, B | 1 |
| Thomas, MH | 1 |
| Gutterman, LA | 1 |
| Lindahl, A | 1 |
1 review available for trimethoprim and Bone Marrow Diseases
| Article | Year |
|---|---|
[Sulfamethoxazole-trimethoprim and megaloblastic anemia].
Topics: Anemia, Macrocytic; Bone Marrow Diseases; Drug Combinations; Folic Acid; Humans; Sulfamethoxazole; T | 1974 |
3 other studies available for trimethoprim and Bone Marrow Diseases
| Article | Year |
|---|---|
Co-trimoxazole.
Topics: Aged; Bone Marrow Diseases; Drug Combinations; Erythrocytes, Abnormal; Female; Folic Acid Deficiency | 1978 |
Acute pancytopenia due to megaloblastic arrest in association with co-trimoxazole.
Topics: Acute Disease; Aged; Anemia, Megaloblastic; Bone Marrow Diseases; Drug Combinations; Erythrocytes, A | 1978 |
Methotrexate toxicity in a patient receiving trimethoprim-sulfamethoxazole.
Topics: Arthritis, Rheumatoid; Bone Marrow Diseases; Drug Combinations; Drug Interactions; Female; Humans; M | 1986 |