trimethoprim has been researched along with Blepharitis in 2 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Blepharitis: Inflammation of the eyelids.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A safety and efficacy study comparing the clinical and bacteriologic effectiveness of trimethoprim-sulfacetamide-polymyxin B-neomycin-gramicidin in a group of patients with surface ocular bacterial infections was conducted." | 9.05 | Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections. ( Austin, R; Knowlton, G; Nozik, RA; Smolin, G, 1985) |
| "We studied trimethoprim in combination with sulfacetamide and polymyxin B and also in combination with polymyxin B alone (without the sulfacetamide) to determine the efficacy and safety of these new antibiotic combinations in the eyes of patients with bacterial conjunctivitis or blepharitis." | 5.05 | Clinical evaluation of trimethoprim-containing ophthalmic solutions in humans. ( Buka, T; Knowlton, GM; Lamberts, DW, 1984) |
| "A safety and efficacy study comparing the clinical and bacteriologic effectiveness of trimethoprim-sulfacetamide-polymyxin B-neomycin-gramicidin in a group of patients with surface ocular bacterial infections was conducted." | 5.05 | Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections. ( Austin, R; Knowlton, G; Nozik, RA; Smolin, G, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lamberts, DW | 1 |
| Buka, T | 1 |
| Knowlton, GM | 1 |
| Nozik, RA | 1 |
| Smolin, G | 1 |
| Knowlton, G | 1 |
| Austin, R | 1 |
2 trials available for trimethoprim and Blepharitis
| Article | Year |
|---|---|
Clinical evaluation of trimethoprim-containing ophthalmic solutions in humans.
Topics: Adolescent; Adult; Aged; Blepharitis; Child; Child, Preschool; Clinical Trials as Topic; Conjunctivi | 1984 |
Trimethoprim-polymyxin B ophthalmic solution in treatment of surface ocular bacterial infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Blepharitis; Child; Conjunctivitis, Bacterial; Double | 1985 |