trimethoprim has been researched along with Bleb in 8 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Skin blisters were induced by applying 0." | 2.70 | [Skin penetration of sulfamethoxazole and trimethoprim after oral administration]. ( Królicki, A, 2002) |
| "We investigated the pharmacokinetic properties of brodimoprim (B), a new diaminopyrimidine, including its penetration into suction blister fluid (SBF) after a single or multiple oral dose in 15 patients with a mean age of 61." | 1.29 | Pharmacokinetics and blister fluid penetration of brodimoprim in adults. ( Cassetta, MI; Fallani, S; Mazzei, T; Meli, E; Novelli, A; Periti, P, 1993) |
| "Plasma and skin blister fluid concentration-time curves following a single oral dose of trimethoprim have been evaluated." | 1.27 | Plasma and skin blister fluid concentrations of trimethoprim following its oral administration. ( Kadyków, M; Klimowicz, A; Nowak, A, 1988) |
| " Considering the minimal inhibitory concentrations of potential target organisms and the slow elimination, the results suggest that brodimoprim may be useful in the treatment of infections, and that dosage once a day may be sufficient." | 1.27 | Pharmacokinetics of brodimoprim in serum and skin blister fluid. ( Bergan, T; Digranes, A; Kalager, T; Salveson, A, 1985) |
| " However, on the basis of dosage the highest sulfonamide concentration both in serum and blister fluid was obtained with sulfamethoxazole." | 1.26 | Sulfonamide and trimethoprim concentrations in human serum and skin blister fluid. ( Bredesen, JE; Bruun, JN; Kierulf, P; Lunde, PK; Ostby, N, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Królicki, A | 1 |
| Nowak, A | 2 |
| Kadyków, M | 2 |
| Klimowicz, A | 2 |
| Bruun, JN | 2 |
| Bergan, T | 2 |
| Ostby, N | 2 |
| Bredesen, JE | 2 |
| Lunde, PK | 2 |
| Kierulf, P | 1 |
| Novelli, A | 1 |
| Mazzei, T | 1 |
| Meli, E | 1 |
| Cassetta, MI | 1 |
| Fallani, S | 1 |
| Periti, P | 1 |
| McNicholl, B | 1 |
| Kalager, T | 1 |
| Digranes, A | 1 |
| Salveson, A | 1 |
1 trial available for trimethoprim and Bleb
| Article | Year |
|---|---|
[Skin penetration of sulfamethoxazole and trimethoprim after oral administration].
Topics: Administration, Oral; Adult; Blister; Exudates and Transudates; Half-Life; Humans; Male; Middle Aged | 2002 |
7 other studies available for trimethoprim and Bleb
| Article | Year |
|---|---|
Penetration of trimethoprim and sulfamethoxazole into skin blister fluid.
Topics: Adolescent; Adult; Aged; Blister; Drug Combinations; Female; Humans; Male; Middle Aged; Sulfamethoxa | 1983 |
Pharmacokinetics of methioprim in human volunteers.
Topics: Blister; Body Fluids; Humans; Kinetics; Models, Biological; Trimethoprim | 1983 |
Sulfonamide and trimethoprim concentrations in human serum and skin blister fluid.
Topics: Adult; Blister; Exudates and Transudates; Female; Humans; Kinetics; Male; Skin; Sulfonamides; Time F | 1981 |
Pharmacokinetics and blister fluid penetration of brodimoprim in adults.
Topics: Adult; Aged; Blister; Exudates and Transudates; Humans; Male; Middle Aged; Trimethoprim | 1993 |
Recurrent herpetic whitlow.
Topics: Acyclovir; Adult; Blister; Diagnosis, Differential; Fingers; Herpes Simplex; Humans; Male; Recurrenc | 1990 |
Plasma and skin blister fluid concentrations of trimethoprim following its oral administration.
Topics: Administration, Oral; Adolescent; Adult; Blister; Female; Half-Life; Humans; Male; Middle Aged; Trim | 1988 |
Pharmacokinetics of brodimoprim in serum and skin blister fluid.
Topics: Administration, Oral; Adult; Blister; Female; Humans; Kinetics; Male; Trimethoprim | 1985 |