Page last updated: 2024-11-05

trimethoprim and Bleb

trimethoprim has been researched along with Bleb in 8 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Research Excerpts

ExcerptRelevanceReference
"Skin blisters were induced by applying 0."2.70[Skin penetration of sulfamethoxazole and trimethoprim after oral administration]. ( Królicki, A, 2002)
"We investigated the pharmacokinetic properties of brodimoprim (B), a new diaminopyrimidine, including its penetration into suction blister fluid (SBF) after a single or multiple oral dose in 15 patients with a mean age of 61."1.29Pharmacokinetics and blister fluid penetration of brodimoprim in adults. ( Cassetta, MI; Fallani, S; Mazzei, T; Meli, E; Novelli, A; Periti, P, 1993)
"Plasma and skin blister fluid concentration-time curves following a single oral dose of trimethoprim have been evaluated."1.27Plasma and skin blister fluid concentrations of trimethoprim following its oral administration. ( Kadyków, M; Klimowicz, A; Nowak, A, 1988)
" Considering the minimal inhibitory concentrations of potential target organisms and the slow elimination, the results suggest that brodimoprim may be useful in the treatment of infections, and that dosage once a day may be sufficient."1.27Pharmacokinetics of brodimoprim in serum and skin blister fluid. ( Bergan, T; Digranes, A; Kalager, T; Salveson, A, 1985)
" However, on the basis of dosage the highest sulfonamide concentration both in serum and blister fluid was obtained with sulfamethoxazole."1.26Sulfonamide and trimethoprim concentrations in human serum and skin blister fluid. ( Bredesen, JE; Bruun, JN; Kierulf, P; Lunde, PK; Ostby, N, 1981)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Królicki, A1
Nowak, A2
Kadyków, M2
Klimowicz, A2
Bruun, JN2
Bergan, T2
Ostby, N2
Bredesen, JE2
Lunde, PK2
Kierulf, P1
Novelli, A1
Mazzei, T1
Meli, E1
Cassetta, MI1
Fallani, S1
Periti, P1
McNicholl, B1
Kalager, T1
Digranes, A1
Salveson, A1

Trials

1 trial available for trimethoprim and Bleb

ArticleYear
[Skin penetration of sulfamethoxazole and trimethoprim after oral administration].
    Annales Academiae Medicae Stetinensis, 2002, Volume: 48

    Topics: Administration, Oral; Adult; Blister; Exudates and Transudates; Half-Life; Humans; Male; Middle Aged

2002

Other Studies

7 other studies available for trimethoprim and Bleb

ArticleYear
Penetration of trimethoprim and sulfamethoxazole into skin blister fluid.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Aged; Blister; Drug Combinations; Female; Humans; Male; Middle Aged; Sulfamethoxa

1983
Pharmacokinetics of methioprim in human volunteers.
    Chemotherapy, 1983, Volume: 29, Issue:3

    Topics: Blister; Body Fluids; Humans; Kinetics; Models, Biological; Trimethoprim

1983
Sulfonamide and trimethoprim concentrations in human serum and skin blister fluid.
    Antimicrobial agents and chemotherapy, 1981, Volume: 19, Issue:1

    Topics: Adult; Blister; Exudates and Transudates; Female; Humans; Kinetics; Male; Skin; Sulfonamides; Time F

1981
Pharmacokinetics and blister fluid penetration of brodimoprim in adults.
    Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:6

    Topics: Adult; Aged; Blister; Exudates and Transudates; Humans; Male; Middle Aged; Trimethoprim

1993
Recurrent herpetic whitlow.
    Archives of emergency medicine, 1990, Volume: 7, Issue:2

    Topics: Acyclovir; Adult; Blister; Diagnosis, Differential; Fingers; Herpes Simplex; Humans; Male; Recurrenc

1990
Plasma and skin blister fluid concentrations of trimethoprim following its oral administration.
    European journal of clinical pharmacology, 1988, Volume: 34, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Blister; Female; Half-Life; Humans; Male; Middle Aged; Trim

1988
Pharmacokinetics of brodimoprim in serum and skin blister fluid.
    Chemotherapy, 1985, Volume: 31, Issue:6

    Topics: Administration, Oral; Adult; Blister; Female; Humans; Kinetics; Male; Trimethoprim

1985