trimethoprim has been researched along with Biliary Atresia in 3 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Biliary Atresia: Progressive destruction or the absence of all or part of the extrahepatic BILE DUCTS, resulting in the complete obstruction of BILE flow. Usually, biliary atresia is found in infants and accounts for one third of the neonatal cholestatic JAUNDICE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacokinetics for combination trimethoprim/ sulfamethoxazole (TMP/SMX) was studied in only four patients with biliary atresia (BA): three girls, 6." | 9.08 | Kinetic effects of trimethoprim-sulfamethoxazole in children with biliary atresia: a new dosing regimen. ( Camacho, A; Lares-Asseff, I; López, DC; Pérez, G; Toledo, A; Villegas, F, 1996) |
| "Pharmacokinetics for combination trimethoprim/ sulfamethoxazole (TMP/SMX) was studied in only four patients with biliary atresia (BA): three girls, 6." | 5.08 | Kinetic effects of trimethoprim-sulfamethoxazole in children with biliary atresia: a new dosing regimen. ( Camacho, A; Lares-Asseff, I; López, DC; Pérez, G; Toledo, A; Villegas, F, 1996) |
| " Adult wild-type (WT) and Cxcr2-/- mice were fed a diet supplemented with sulfamethoxazole/trimethoprim (SMZ/TMP) during pregnancy and lactation, and their pups were injected intraperitoneally with rhesus rotavirus (RRV) within 24 hours of life to induce experimental biliary atresia." | 3.85 | Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia. ( Bezerra, JA; Fei, L; Jee, J; Mourya, R; Shivakumar, P; Wagner, M, 2017) |
| "The records of all patients with biliary atresia seen at the Childrens Hospital of Los Angeles during a 14-year period were reviewed." | 1.28 | Perioperative factors affecting the outcome following repair of biliary atresia. ( Atkinson, JB; Kanegaye, J; Lally, KP; Matsumura, M; Rosenthal, P; Sinatra, F, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jee, J | 1 |
| Mourya, R | 1 |
| Shivakumar, P | 1 |
| Fei, L | 1 |
| Wagner, M | 1 |
| Bezerra, JA | 1 |
| Lares-Asseff, I | 1 |
| Villegas, F | 1 |
| Pérez, G | 1 |
| Toledo, A | 1 |
| Camacho, A | 1 |
| López, DC | 1 |
| Lally, KP | 1 |
| Kanegaye, J | 1 |
| Matsumura, M | 1 |
| Rosenthal, P | 1 |
| Sinatra, F | 1 |
| Atkinson, JB | 1 |
1 trial available for trimethoprim and Biliary Atresia
| Article | Year |
|---|---|
Kinetic effects of trimethoprim-sulfamethoxazole in children with biliary atresia: a new dosing regimen.
Topics: Biliary Atresia; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Mal | 1996 |
2 other studies available for trimethoprim and Biliary Atresia
| Article | Year |
|---|---|
Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia.
Topics: Animals; Bile Ducts; Biliary Atresia; Disease Models, Animal; Female; Gene Expression Profiling; Inf | 2017 |
Perioperative factors affecting the outcome following repair of biliary atresia.
Topics: Biliary Atresia; Cholangitis; Humans; Infant; Portoenterostomy, Hepatic; Postoperative Complications | 1989 |