Page last updated: 2024-11-05

trimethoprim and Bacteremia

trimethoprim has been researched along with Bacteremia in 14 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
"Tension pneumocephalus should be included in the differential diagnosis of nontraumatic hemiparesis for emergent evaluation and management."1.46Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma. ( Fernandez, J; Nanjappa, S; Pabbathi, S; Srikumar, T, 2017)
"Ampicillin resistance was relatively stable over time, but varied between Health Regions."1.31Regional variation in ampicillin and trimethoprim resistance in Escherichia coli in England from 1990 to 1997, in relation to antibacterial prescribing. ( George, RC; Gifford, T; James, D; Johnson, AP; Livermore, DM; Northcott, D; Speller, DC; Stephens, P; Weinberg, J, 2000)
"aureus bacteremia were compared against 188 controls selected from patients with CD4 cell counts < 200 x 10(6)/l."1.30Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients. ( Chaisson, RE; Moore, RD; Styrt, BA, 1997)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's8 (57.14)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Chang, TH1
Chuang, YC1
Wang, JT1
Sheng, WH1
McCowan, C1
Bakhshi, A1
McConnachie, A1
Malcolm, W1
Barry, SJ1
Santiago, VH1
Leanord, A1
Mokraoui, NR1
Ganim, R1
Paez, A1
Iki, Y1
Hata, A1
Fukuyama, M1
Yoshioka, T1
Watanabe, K1
Asari, S1
Hata, D1
Watson, L1
Esterly, J1
Jensen, AO1
Postelnick, M1
Aguirre, A1
McLaughlin, M1
Lishman, H1
Costelloe, C1
Hopkins, S1
Johnson, AP2
Hope, R1
Guy, R1
Muller-Pebody, B1
Holmes, A1
Aylin, P1
Rijnders, B1
DiSciullo, GJ1
Csiky, B1
Rutkowski, B1
Appelt, K1
Cheronis, J1
Aitchison, R1
Gordon, G1
Jadoul, M1
Fluck, R1
Vinker-Shuster, M1
Stepensky, P1
Temper, V1
Shayovitz, V1
Masarwa, R1
Averbuch, D1
Kuretski, J1
Dahya, V1
Cason, L1
Chalasani, P1
Ramgopal, M1
Srikumar, T1
Pabbathi, S1
Fernandez, J1
Nanjappa, S1
Melendez, J1
Claxton, A1
Erskine, K1
Styrt, BA1
Chaisson, RE1
Moore, RD1
Pedersen, G1
Schønheyder, HC1
Steffensen, FH1
Sørensen, HT1
Livermore, DM1
Stephens, P1
Weinberg, J1
Gifford, T1
Northcott, D1
James, D1
George, RC1
Speller, DC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-Center, Prospective, Randomized, Open-Label, Sponsor-Blinded, Active-Control (Heparin) Clinical Investigation to Evaluate the Safety and Effectiveness of B-Lock™ as an Antimicrobial Catheter Lock Solution in Dialysis Patients With a Central Venous C[NCT01989091]Phase 3270 participants (Actual)Interventional2012-07-31Terminated (stopped due to Did not meet predetermined primary endpoint)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for trimethoprim and Bacteremia

ArticleYear
Locking Hemodialysis Catheters With Trimethoprim-Ethanol-Ca-EDTA to Prevent Bloodstream Infections: A Randomized, Evaluator-blinded Clinical Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 06-18, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Infective Agents, Local; Bac

2019
Gram-negative Bacteremia in Children With Hematologic Malignancies and Following Hematopoietic Stem Cell Transplantation: Epidemiology, Resistance, and Outcome.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:8

    Topics: Adolescent; Allografts; Bacteremia; Child; Child, Preschool; Drug Combinations; Drug Resistance, Bac

2019

Other Studies

12 other studies available for trimethoprim and Bacteremia

ArticleYear
Clinical characteristics and outcomes of non-cystic fibrosis patients with Burkholderia cepacia complex bacteremia at a medical center in Taiwan.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2022, Volume: 55, Issue:6 Pt 2

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Burkholderia cepacia; Burkholderia cepacia complex;

2022
E. coli bacteraemia and antimicrobial resistance following antimicrobial prescribing for urinary tract infection in the community.
    BMC infectious diseases, 2022, Oct-28, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacteremia; Drug Res

2022
Chest wall abscess and costochondritis due to Salmonella enterica serotype Choleraesuis: a case report.
    Journal of medical case reports, 2023, Dec-06, Volume: 17, Issue:1

    Topics: Abscess; Aged; Bacteremia; Female; Gastrointestinal Diseases; Humans; Salmonella; Salmonella enteric

2023
Successful Conservative Treatment of Mycotic Pulmonary Artery Aneurysms Caused by MRSA Bacteremia.
    Pediatrics, 2019, Volume: 144, Issue:5

    Topics: Aneurysm, Infected; Anti-Bacterial Agents; Bacteremia; Clindamycin; Conservative Treatment; Drug Com

2019
Sulfamethoxazole/trimethoprim versus fluoroquinolones for the treatment of Stenotrophomonas maltophilia bloodstream infections.
    Journal of global antimicrobial resistance, 2018, Volume: 12

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Drug Therapy, Combination; Female; Fluoroquinolones;

2018
Exploring the relationship between primary care antibiotic prescribing for urinary tract infections, Escherichia coli bacteraemia incidence and antimicrobial resistance: an ecological study.
    International journal of antimicrobial agents, 2018, Volume: 52, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Drug Resistance, Bacterial; Engla

2018
Nocardia Bacteremia and Endocarditis in a Patient With a Sulfa Allergy.
    The American journal of the medical sciences, 2016, Volume: 352, Issue:5

    Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Hypersensitivity; Dyspnea; Endocard

2016
Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma.
    The American journal of case reports, 2017, Jan-10, Volume: 18

    Topics: Aged; Anti-Bacterial Agents; Aspergillosis; Aspergillus; Bacteremia; Brain Abscess; Cefepime; Cephal

2017
MRSA bacteraemia after caesarean section wound infection: when screening is missed and things go wrong.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:3

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cefuroxime; Cesarean Sec

2012
Prior antimicrobials and staphylococcal bacteremia in HIV-infected patients.
    AIDS (London, England), 1997, Volume: 11, Issue:10

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Bacteremia; Case-Control Studie

1997
Risk of resistance related to antibiotic use before admission in patients with community-acquired bacteraemia.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:1

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Bacteremia; Community-Acquired Infections; Denmark; Drug Pr

1999
Regional variation in ampicillin and trimethoprim resistance in Escherichia coli in England from 1990 to 1997, in relation to antibacterial prescribing.
    The Journal of antimicrobial chemotherapy, 2000, Volume: 46, Issue:3

    Topics: Ampicillin; Ampicillin Resistance; Anti-Infective Agents, Urinary; Bacteremia; Drug Prescriptions; D

2000