trimethoprim has been researched along with Anemia, Megaloblastic in 18 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Anemia, Megaloblastic: A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we describe the occurrence of severe combined immunodeficiency (SCID) with megaloblastic anemia, leukopenia, atypical hemolytic uremic syndrome, and neurologic abnormalities in which hydroxocobalamin and folate therapy provided partial immune reconstitution." | 3.79 | Severe combined immunodeficiency resulting from mutations in MTHFD1. ( Baluarte, HJ; Bergqvist, AG; Ganesh, J; Heltzer, M; Keller, MD; Orange, JS; Paessler, M; Rosenblatt, DS; Watkins, D, 2013) |
| "Treatment of drug-induced aplastic anemia requires transfusions." | 2.35 | Drug-induced anaemias. ( Girdwood, RH, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (88.89) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keller, MD | 1 |
| Ganesh, J | 1 |
| Heltzer, M | 1 |
| Paessler, M | 1 |
| Bergqvist, AG | 1 |
| Baluarte, HJ | 1 |
| Watkins, D | 1 |
| Rosenblatt, DS | 1 |
| Orange, JS | 1 |
| Dan, M | 1 |
| Shapira, I | 1 |
| Kobrinsky, NL | 1 |
| Ramsay, NK | 1 |
| Anguita, T | 1 |
| Magee, F | 1 |
| O'Sullivan, H | 1 |
| McCann, SR | 1 |
| Chan, MK | 1 |
| Beale, D | 1 |
| Moorhead, JF | 1 |
| Schütz, H | 1 |
| Ansdell, VE | 1 |
| Wright, SG | 1 |
| Hutchinson, DB | 1 |
| Heilmann, E | 1 |
| Hellmann, A | 1 |
| Nering, I | 1 |
| Blackwell, EA | 2 |
| Hawson, GA | 2 |
| Leer, J | 2 |
| Bain, B | 1 |
| Masera, G | 1 |
| Baronciani, D | 1 |
| Conti, A | 1 |
| Jankovic, M | 1 |
| Uderzo, C | 1 |
| Bain, BJ | 1 |
| Girdwood, RH | 2 |
| Malfatti, S | 1 |
| Piccini, A | 1 |
| Crosby, WH | 1 |
| Borgstein, A | 1 |
| Tozer, RA | 1 |
2 reviews available for trimethoprim and Anemia, Megaloblastic
| Article | Year |
|---|---|
[Drug-induced megaloblastic anemia].
Topics: Alcoholism; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Anticonvulsants; Antim | 1979 |
Drug-induced anaemias.
Topics: Anemia; Anemia, Aplastic; Anemia, Megaloblastic; Anemia, Sideroblastic; Anticonvulsants; Bone Marrow | 1976 |
16 other studies available for trimethoprim and Anemia, Megaloblastic
| Article | Year |
|---|---|
Severe combined immunodeficiency resulting from mutations in MTHFD1.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Anemia, Megaloblastic; Bone Marrow Examination; Cardiomyopathies; | 2013 |
Possible role of methotrexate in trimethoprim-sulfamethoxazole-induced acute megaloblastic anemia.
Topics: Acute Disease; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Drug Synergism; Female; | 1984 |
Acute megaloblastic anemia induced by high-dose trimethoprim-sulfamethoxazole.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Female; Humans; Leucovorin; Sul | 1981 |
[Bone marrow megaloblastosis associated with the use of pyrimethamine, triamterene and trimethoprim-sulfamethoxazole].
Topics: Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Drug Combinations; Female; Foli | 1982 |
Megaloblastosis and low-dose trimethoprim-sulfamethoxazole.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Sulfamethoxazole; Trimethoprim | 1981 |
Acute megaloblastosis due to cotrimoxazole.
Topics: Acute Disease; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Female; Folic Acid Defi | 1980 |
[Clinical demonstration (author's transl)].
Topics: Acute Kidney Injury; Adult; Aged; Alveolitis, Extrinsic Allergic; Anemia, Macrocytic; Anemia, Megalo | 1978 |
Megaloblastic anaemia associated with combined pyrimethamine and co-trimoxazole administration.
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Drug Therapy, Combination; Fema | 1976 |
[Complete bone marrow suppression and megaloblastic anemia as a result of long-term treatment with cotrimoxazole].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Drug Combinations; Humans; Male; Middle Aged | 1977 |
Acute pancytopenia due to megaloblastic arrest in association with co-trimoxazole.
Topics: Acute Disease; Aged; Anemia, Megaloblastic; Bone Marrow Diseases; Drug Combinations; Erythrocytes, A | 1978 |
[Hemopathies caused by drugs in children: aplastic anemia, agranulocytosis, megaloblastic anemia].
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; | 1978 |
Co-trimoxazole.
Topics: Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Humans; Sulfamethoxazole; Trimethoprim | 1978 |
[Pancytopenic megaloblastic anaemia following administration of pyrimethamine, trimethoprim and sulphamethoxazole (author's transl)].
Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Synergism; Folic Acid Antagonists; Humans; Ma | 1976 |
The nature of possible adverse reactions to co-trimoxazole.
Topics: Aminopterin; Anemia, Megaloblastic; Chemical Phenomena; Chemistry; Drug Combinations; Folic Acid; Hu | 1976 |
Megaloblastic pancytopenia associated with dapsone and trimethoprim treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Anemia, Macrocytic; Anemia, Megaloblastic; Dapsone; Humans; Leuc | 1990 |
Infectious mononucleosis and megaloblastic anaemia associated with daraprim and bactrim.
Topics: Adolescent; Anemia, Macrocytic; Anemia, Megaloblastic; Drug Combinations; Female; Folic Acid Deficie | 1974 |