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trimethoprim and Anemia, Aplastic

trimethoprim has been researched along with Anemia, Aplastic in 20 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Anemia, Aplastic: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements.

Research Excerpts

ExcerptRelevanceReference
"Treatment of drug-induced aplastic anemia requires transfusions."2.35Drug-induced anaemias. ( Girdwood, RH, 1976)
"Records of 8 dogs with drug-associated aplastic anemia were reviewed."1.28Drug-associated aplastic anemia in dogs: eight cases (1984-1988). ( Klausner, JS; Weiss, DJ, 1990)
"The risks of agranulocytosis and aplastic anemia in relation to the use of anti-infective drugs were estimated in a population-based case-control study conducted in Europe and Israel."1.28Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study. ( , 1989)
"A sever Pneumocystis carinii pneumonitis developed, but was successfully treated with pentamidine, sulfametoxazole with trimetoprim and transfer factor."1.26Indication of primary immune deficiency in Fanconi's anemia. ( Hertz, H; Lundsteen, C; Pedersen, FK; Platz, P; Thomsen, M, 1977)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199018 (90.00)18.7374
1990's2 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Winston, DJ1
Ho, WG1
Champlin, RE1
Gale, RP1
Markman, M1
Mannisi, J1
Dick, JD1
Filburn, B1
Santos, GW1
Saral, R1
Pedersen, FK1
Hertz, H1
Lundsteen, C1
Platz, P1
Thomsen, M1
Masera, G1
Baronciani, D1
Conti, A1
Jankovic, M1
Uderzo, C1
Girdwood, RH1
Tulloch, AL1
Weiss, DJ2
Klausner, JS1
Bashey, A1
McMullin, MF1
Hows, JM1
Adams, LG1
Serrate San Miguel, G1
Franco Comet, P1
Puigbó Casañé, MD1
Font Creus, B1
Gordon-Smith, EC1
Knolle, P1
Frisch, JM1
Stephens, ME1
Wilfert, CM1
Hill, AV1
Kerr, DN1
Lapage, SP1
Owen, RJ1
Toghill, PJ1
Ryrie, DR1
Tanna, MK1
Tattersall, RB1

Reviews

2 reviews available for trimethoprim and Anemia, Aplastic

ArticleYear
Infectious complications of bone marrow transplantation.
    Experimental hematology, 1984, Volume: 12, Issue:3

    Topics: Aminoglycosides; Amphotericin B; Anemia, Aplastic; Bacterial Infections; Bone Marrow Transplantation

1984
Drug-induced anaemias.
    Drugs, 1976, Volume: 11, Issue:5

    Topics: Anemia; Anemia, Aplastic; Anemia, Megaloblastic; Anemia, Sideroblastic; Anticonvulsants; Bone Marrow

1976

Other Studies

18 other studies available for trimethoprim and Anemia, Aplastic

ArticleYear
Sulfamethoxazole-trimethoprim-resistant pneumococcal sepsis.
    JAMA, 1982, Dec-10, Volume: 248, Issue:22

    Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Drug Resistance, Microbial; Female; Graft

1982
Indication of primary immune deficiency in Fanconi's anemia.
    Acta paediatrica Scandinavica, 1977, Volume: 66, Issue:6

    Topics: Abnormalities, Multiple; Adrenal Cortex Hormones; Androgens; Anemia, Aplastic; Child; Chromosome Abe

1977
[Hemopathies caused by drugs in children: aplastic anemia, agranulocytosis, megaloblastic anemia].
    Minerva pediatrica, 1978, Sep-30, Volume: 30, Issue:18

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents;

1978
Pancytopenia in an infant associated with sulfamethoxazole-trimethoprim therapy.
    The Journal of pediatrics, 1976, Volume: 88, Issue:3

    Topics: Anemia, Aplastic; Cough; Drug Combinations; Histiocytes; Humans; Infant; Male; Plasma Cells; Sulfame

1976
Drug-associated aplastic anemia in dogs: eight cases (1984-1988).
    Journal of the American Veterinary Medical Association, 1990, Feb-01, Volume: 196, Issue:3

    Topics: Anemia, Aplastic; Animals; Anti-Infective Agents; Antimalarials; Dog Diseases; Dogs; Drug Combinatio

1990
Pneumocystis prophylaxis after bone marrow transplantation for severe aplastic anaemia.
    Bone marrow transplantation, 1990, Volume: 5, Issue:4

    Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Drug Combinations; Female; Humans;

1990
Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study.
    Archives of internal medicine, 1989, Volume: 149, Issue:5

    Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Anti-Infective Agents; Drug Combinations;

1989
Aplastic anemia associated with trimethoprim-sulfadiazine and fenbendazole administration in a dog.
    Journal of the American Veterinary Medical Association, 1987, Nov-01, Volume: 191, Issue:9

    Topics: Anemia, Aplastic; Animals; Anti-Infective Agents; Benzimidazoles; Bronchiectasis; Bronchitis; Dog Di

1987
[Pure red-cell aplasia associated with cotrimoxazole].
    Medicina clinica, 1985, Mar-02, Volume: 84, Issue:8

    Topics: Anemia, Aplastic; Drug Combinations; Female; Humans; Middle Aged; Sulfamethoxazole; Trimethoprim; Tr

1985
Treatment of aplastic anemias.
    Hospital practice (Office ed.), 1985, May-15, Volume: 20, Issue:5

    Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Antifungal Agents; Antilymphocyte Serum; Bone Marrow

1985
Editorial: Co-trimoxazole and blood.
    Lancet (London, England), 1973, Oct-27, Volume: 2, Issue:7835

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Bone Marrow; Drug Combinations; Female; Folic

1973
Side reactions of chloramphenicol in mouse erythroblasts.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:4

    Topics: Anemia, Aplastic; Animals; Antimetabolites; Binding Sites; Cell Division; Cell Line; Cells; Chloramp

1974
Clinical experience with adverse reactions to trimethoprim-sulfamethoxazole.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Aged; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Child; Depression; Drug Combinations; D

1973
Transient erythroid hypoplasia in a patient on long-term co-trimoxazole therapy.
    Postgraduate medical journal, 1974, Volume: 50, Issue:582

    Topics: Anemia, Aplastic; Blood Transfusion; Crohn Disease; Erythrocyte Count; Female; Hematocrit; Hemoglobi

1974
Trimethoprim-sulfamethoxazole in children: pharmacokinetics and clinical studies.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Anemia, Aplastic; Anemia, Sickle Cell; Bacterial Infections; Child; Child, Preschool; Drug Combinati

1973
Toxicity of co-trimoxazole in nutritional haematinic deficiency.
    Postgraduate medical journal, 1973, Volume: 49, Issue:574

    Topics: Anemia, Aplastic; Anemia, Macrocytic; Blood Cell Count; Folic Acid; Folic Acid Deficiency; Humans; I

1973
Flavobacterium meningosepticum from cases of meningitis in Botswana and England.
    Journal of clinical pathology, 1973, Volume: 26, Issue:10

    Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Bangladesh; Botswana; England; Flavobacterium; Human

1973
Induction of remission in myeloblastic and monoblastic leukaemia in adults with rubidomycin.
    Acta haematologica, 1971, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Aged; Alopecia; Ampicillin; Anemia, Aplastic; Antibiotics, Antineoplastic; Blood

1971