trimethoprim has been researched along with Allergy, Drug in 84 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 9.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 7.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy." | 7.67 | Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989) |
| "Intravenous administration of trimethoprim-sulfamethoxazole (TMS) on three occasions resulted in fever, rash, and wheezing in a 30-year-old man with acquired immunodeficiency syndrome with Pneumocytis carinii pneumonia." | 7.67 | Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome. ( Finegold, I, 1986) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 5.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "Trimethoprim is the antibiotic of choice for treating uncomplicated community acquired urinary tract infections." | 3.73 | Fatal adverse drug reaction to trimethoprim. ( Bermingham, MR; Chapple, SJ; Mortimer, NJ; Sladden, MJ, 2005) |
| " the LTA by using trypan blue exclusion and to determine the utility of the assay to confirm drug hypersensitivity syndrome (DHS) to sulphonamides (SMX) and aromatic anticonvulsants." | 3.70 | A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes. ( Malkiewicz, IM; Neuman, MG; Shear, NH, 2000) |
| " Only 5 of 37 patients started on trimethoprim-sulfamethoxazole were able to complete treatment; in 29 patients drug toxicity occurred and in 19 treatment was changed due to adverse reactions that included rash, fever, neutropenia, thrombocytopenia, and transaminase elevation." | 3.67 | Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome. ( Gordin, FM; Mills, J; Simon, GL; Wofsy, CB, 1984) |
| "In three of eight patients with the acquired immune deficiency syndrome the Pneumocystis carinii pneumonia treated with intravenous trimethoprim sulfamethoxazole, drug-related reactions occurred 9, 10, and 13 days after therapy." | 3.67 | Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia. ( Brunner, E; Haddad, ZH; Sainz, C; White, MV, 1989) |
| "A patient with acquired immunodeficiency syndrome (AIDS) developed rash, fever, neutropenia, and elevated liver function tests during an initial course of trimethoprim-sulfamethoxazole (TMP-SMX) therapy." | 3.67 | Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS. ( Arnold, PA; Guglielmo, BJ; Hollander, H, 1988) |
| "Intravenous administration of trimethoprim-sulfamethoxazole (TMS) on three occasions resulted in fever, rash, and wheezing in a 30-year-old man with acquired immunodeficiency syndrome with Pneumocytis carinii pneumonia." | 3.67 | Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome. ( Finegold, I, 1986) |
| "After an acute course of pharyngitis and bronchitis treated with Bactrim (trimethoprim and sulfamethoxazol), a 52 year old woman suddenly developed a widespread, sterile pustular eruption with predilection of the distal parts of the extremities." | 3.66 | [Generalized acute pustulosis. An unusual presentation of leukocytoclastic vasculitis]. ( Braun-Falco, O; Luderschmidt, C; Maciejewski, W; Scherer, R, 1978) |
| "The onset of cutaneous adverse effects attributable to sulfamethoxazole-trimethoprim therapy within 3 months after desensitization." | 2.68 | Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus. ( Bricaire, F; Caumes, E; Guermonprez, G; Katlama, C; Lecomte, C, 1997) |
| "Treatment of drug-induced aplastic anemia requires transfusions." | 2.35 | Drug-induced anaemias. ( Girdwood, RH, 1976) |
| "Trimethoprim clones were additionally stimulated with diaveridine and pyrimethamine but not other closely related structures." | 1.37 | Trimethoprim stimulates T-cells through metabolism-dependent and -independent pathways. ( El-Ghaiesh, S; Farrell, J; Lavergne, SN; Naisbitt, DJ; Park, BK; Pirmohamed, M; Sanderson, JP; Syn, WK, 2011) |
| "Thirty-four homosexual patients with AIDS were treated for Pneumocystis carinii pneumonia between April 1984 and November 1985." | 1.28 | Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions. ( Seitzman, PA; Shafer, RW; Tapper, ML, 1989) |
| "Clinical features of 49 episodes of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome were compared with those of 39 episodes in patients with other immunosuppressive diseases." | 1.27 | Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. ( Hiemenz, JW; Honig, C; Kovacs, JA; Lane, HC; Longo, DL; Macher, AM; Murray, HW; Shelhamer, J; Stover, D; Urmacher, C, 1984) |
| "Treatment with sulfadiazine-trimethoprim caused serious, but reversible, allergic drug reactions in 6 Doberman Pinschers 10 to 21 days after the first drug exposure and/or within 1 hour to 10 days after reexposure." | 1.27 | Sulfadiazine-induced allergy in six Doberman pinschers. ( Giger, U; Gorman, NT; Millichamp, NJ; Werner, LL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (72.62) | 18.7374 |
| 1990's | 13 (15.48) | 18.2507 |
| 2000's | 3 (3.57) | 29.6817 |
| 2010's | 5 (5.95) | 24.3611 |
| 2020's | 2 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Pereira, ARF | 1 |
| Aun, MV | 1 |
| Kelmann, NCP | 1 |
| Motta, AA | 1 |
| Kalil, J | 1 |
| Giavina-Bianchi, P | 1 |
| Pumar, M | 1 |
| Varese, N | 1 |
| Hew, M | 1 |
| O'Hehir, RE | 1 |
| Zubrinich, C | 1 |
| Mathanasenarajah, G | 1 |
| Hoi, A | 1 |
| Henao, MP | 1 |
| Ghaffari, G | 1 |
| Kuretski, J | 1 |
| Dahya, V | 1 |
| Cason, L | 1 |
| Chalasani, P | 1 |
| Ramgopal, M | 1 |
| El-Ghaiesh, S | 2 |
| Sanderson, JP | 2 |
| Farrell, J | 2 |
| Lavergne, SN | 2 |
| Syn, WK | 2 |
| Pirmohamed, M | 2 |
| Park, BK | 2 |
| Naisbitt, DJ | 2 |
| Nordstrand, IA | 1 |
| Mortimer, NJ | 1 |
| Bermingham, MR | 1 |
| Chapple, SJ | 1 |
| Sladden, MJ | 1 |
| Clark, AJ | 1 |
| Mouchizadeh, J | 1 |
| Faunch, R | 1 |
| McMichael, HB | 1 |
| Brumfitt, W | 2 |
| Hamilton-Miller, JM | 1 |
| Wood, A | 1 |
| Lennon, D | 1 |
| Gordin, FM | 1 |
| Simon, GL | 1 |
| Wofsy, CB | 1 |
| Mills, J | 1 |
| Kovacs, JA | 1 |
| Hiemenz, JW | 1 |
| Macher, AM | 1 |
| Stover, D | 1 |
| Murray, HW | 1 |
| Shelhamer, J | 1 |
| Lane, HC | 1 |
| Urmacher, C | 1 |
| Honig, C | 1 |
| Longo, DL | 1 |
| Burt, RA | 1 |
| Boghaert, A | 1 |
| Moulaert, P | 1 |
| Nollet, G | 1 |
| Bellon, A | 1 |
| Kremer, I | 1 |
| Ritz, R | 1 |
| Brunner, F | 1 |
| Cohn, DL | 1 |
| Penley, KA | 1 |
| Judson, FN | 1 |
| Kirkpatrick, CH | 1 |
| Horsburgh, CR | 1 |
| Davis, KC | 1 |
| Warrington, RJ | 1 |
| Sauder, PJ | 1 |
| McPhillips, S | 1 |
| Adiga, KM | 1 |
| de Jersey, P | 1 |
| Wooller, HO | 1 |
| Román, H | 1 |
| Miltényi, M | 1 |
| Görgényi, A | 1 |
| Chanu, B | 1 |
| Kernbaum, S | 1 |
| Uzzan, B | 1 |
| Faille, A | 1 |
| Blasetti, A | 1 |
| Rouffy, J | 1 |
| Nenci, GG | 1 |
| Agnelli, G | 1 |
| Berrettini, M | 1 |
| Korraa, H | 1 |
| Saadeh, C | 1 |
| Pham, NH | 1 |
| Baldo, BA | 3 |
| Manfredi, M | 1 |
| Zerboni, R | 1 |
| Cribb, AE | 1 |
| Lee, BL | 1 |
| Trepanier, LA | 1 |
| Spielberg, SP | 1 |
| Caumes, E | 1 |
| Guermonprez, G | 1 |
| Lecomte, C | 1 |
| Katlama, C | 1 |
| Bricaire, F | 1 |
| Rich, JD | 1 |
| Sullivan, T | 1 |
| Greineder, D | 1 |
| Kazanjian, PH | 1 |
| Antonen, JA | 1 |
| Markula, KP | 1 |
| Pertovaara, MI | 1 |
| Pasternack, AI | 1 |
| Alfaya, T | 1 |
| Pulido, Z | 1 |
| González-Mancebo, E | 1 |
| Cuevas, M | 1 |
| Quirce, S | 1 |
| de la Hoz, B | 1 |
| Neuman, MG | 1 |
| Malkiewicz, IM | 1 |
| Shear, NH | 1 |
| Richmond, JM | 1 |
| Whitworth, JA | 1 |
| Fairley, KF | 1 |
| Kincaid-Smith, P | 1 |
| Kunz, HD | 1 |
| Friess, G | 1 |
| Hirschfeld, E | 1 |
| Chaubey, BS | 1 |
| Grover, S | 1 |
| Patil, SM | 1 |
| Azinge, NO | 1 |
| Garrick, GA | 1 |
| Stevenson, DK | 1 |
| Christie, DL | 1 |
| Haas, JE | 1 |
| Braun-Falco, O | 1 |
| Luderschmidt, C | 1 |
| Maciejewski, W | 1 |
| Scherer, R | 1 |
| Girdwood, RH | 1 |
| Juul, P | 1 |
| Weber, HD | 1 |
| Meyer, FP | 1 |
| Walther, H | 1 |
| Lynn, KL | 1 |
| Little, PJ | 1 |
| Brathwaite, AR | 1 |
| Dry, J | 1 |
| Leynadier, F | 1 |
| Herman, D | 1 |
| Pradalier, A | 1 |
| André, JM | 1 |
| Hofer, T | 1 |
| Becker, EW | 1 |
| Weigand, K | 1 |
| Berg, PA | 2 |
| Greenberger, PA | 1 |
| Little, CJ | 1 |
| Carmichael, S | 1 |
| Gray, A | 1 |
| Higgins, T | 1 |
| Niklasson, PM | 1 |
| Leslie, MD | 1 |
| Williams, DS | 1 |
| Patel, P | 1 |
| White, MV | 1 |
| Haddad, ZH | 1 |
| Brunner, E | 1 |
| Sainz, C | 1 |
| Shafer, RW | 1 |
| Seitzman, PA | 1 |
| Tapper, ML | 1 |
| Taraszewski, R | 1 |
| Harvey, R | 1 |
| Rosman, P | 1 |
| Ulstad, DR | 1 |
| Ampel, NM | 1 |
| Shon, BY | 1 |
| Galgiani, JN | 1 |
| Cutcher, AB | 1 |
| Papakonstantinou, G | 2 |
| Füessl, H | 2 |
| Matuschke, A | 1 |
| Hehlmann, R | 2 |
| Gottlieb, MS | 1 |
| Young, LS | 1 |
| Arnold, PA | 1 |
| Guglielmo, BJ | 1 |
| Hollander, H | 1 |
| Pioda, GB | 2 |
| Del Favero, A | 2 |
| Menichetti, F | 2 |
| Spinozzi, F | 1 |
| Gernini, I | 2 |
| Rambotti, P | 2 |
| Tanabe, K | 1 |
| Nakagawa, A | 1 |
| Kimura, S | 1 |
| Mitamura, K | 1 |
| Shimada, K | 1 |
| Mori, S | 1 |
| Wakabayashi, T | 1 |
| Inagaki, M | 1 |
| Miura, T | 1 |
| Smal, MA | 2 |
| Harle, DG | 2 |
| Sanders, PS | 1 |
| Daniel, PT | 1 |
| Guerciolini, R | 1 |
| Wälti, M | 1 |
| Neftel, KA | 1 |
| Cohen, M | 1 |
| Winkler, P | 1 |
| de Weck, AL | 1 |
| Van Nunen, SA | 1 |
| Finegold, I | 1 |
| Gibbons, RB | 1 |
| Lindauer, JA | 1 |
| Acero, D | 1 |
| Masabeu, A | 1 |
| Alabern, C | 1 |
| Oterino, A | 1 |
| Mayer, KH | 1 |
| DeTorres, OH | 1 |
| Giger, U | 1 |
| Werner, LL | 1 |
| Millichamp, NJ | 1 |
| Gorman, NT | 1 |
| Klein, U | 1 |
| Gikalov, I | 1 |
| Keller, M | 1 |
| Hoigné, R | 1 |
| Halpern, G | 1 |
| Münnich, D | 1 |
| Da Vela, G | 1 |
| Azzi, A | 1 |
| Marini, F | 1 |
| Pursell, R | 1 |
| Schulz, KH | 1 |
| Wilkinson, AE | 1 |
| Lalla, M | 1 |
| Virolainen, M | 1 |
| Gavras, H | 1 |
| Lawson, DH | 1 |
| Linton, AL | 1 |
4 reviews available for trimethoprim and Allergy, Drug
| Article | Year |
|---|---|
Options in the management of pneumonia caused by Pneumocystis carinii in patients with acquired immune deficiency syndrome and intolerance to trimethoprim/sulfamethoxazole.
Topics: Adrenal Cortex Hormones; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal Ag | 1996 |
Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis.
Topics: Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Humans; Sulfamethoxazole; Sulfamoxo | 1996 |
Drug-induced anaemias.
Topics: Anemia; Anemia, Aplastic; Anemia, Megaloblastic; Anemia, Sideroblastic; Anticonvulsants; Bone Marrow | 1976 |
Current guidelines on the use of antibacterial drugs in patients with malignancies.
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Antibody Formation; Bacterial Infecti | 1985 |
7 trials available for trimethoprim and Allergy, Drug
| Article | Year |
|---|---|
Trimethoprim alone.
Topics: Adult; Clinical Trials as Topic; Drug Combinations; Drug Hypersensitivity; Humans; Male; Sulfamethox | 1980 |
Review of adverse reactions associated with cinoxacin and other drugs used to treat urinary tract infections.
Topics: Adult; Aged; Amoxicillin; Anti-Infective Agents, Urinary; Central Nervous System Diseases; Cinoxacin | 1984 |
Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Cinoxacin; Clinical Trials as | 1982 |
Efficacy and safety of desensitization with sulfamethoxazole and trimethoprim in 48 previously hypersensitive patients infected with human immunodeficiency virus.
Topics: Adult; Anti-Infective Agents; Desensitization, Immunologic; Drug Administration Schedule; Drug Erupt | 1997 |
Treatment of gonorrhea in the male with trimethoprim-sulfamethoxazole using a one- or two-dose regimen.
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Drug Combinations; Drug Evaluatio | 1975 |
[Radioimmunologic detection of IgE and IgG antibodies against drugs. Conclusions after experience with over 1200 patients].
Topics: Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Drug Hypersensitivity; Flavonoids; Hum | 1986 |
Double-blind trial to compare ampicillin, cephalexin, co-trimoxazole, and trimethoprim in treatment of urinary infection.
Topics: Ampicillin; Bacteriuria; Cephalexin; Cephalosporins; Drug Hypersensitivity; Escherichia coli Infecti | 1972 |
73 other studies available for trimethoprim and Allergy, Drug
| Article | Year |
|---|---|
Loss of tolerance 5 days after discontinuing sulphonamide introduced via desensitization in delayed reaction.
Topics: Aged; Desensitization, Immunologic; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Sulfamethox | 2020 |
Trimethoprim anaphylaxis confirmed by a novel basophil activation test.
Topics: Anaphylaxis; Anti-Infective Agents, Urinary; Basophil Degranulation Test; Drug Hypersensitivity; Fem | 2021 |
Trimethoprim-induced aseptic meningitis: a reminder case review.
Topics: Aged, 80 and over; Anti-Infective Agents, Urinary; Drug Hypersensitivity; Female; Humans; Meningitis | 2017 |
Anaphylaxis to polymyxin B-trimethoprim eye drops.
Topics: Anaphylaxis; Child, Preschool; Conjunctivitis, Bacterial; Drug Combinations; Drug Hypersensitivity; | 2016 |
Nocardia Bacteremia and Endocarditis in a Patient With a Sulfa Allergy.
Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Hypersensitivity; Dyspnea; Endocard | 2016 |
Trimethoprim stimulates T-cells through metabolism-dependent and -independent pathways.
Topics: Adult; Anti-Infective Agents, Urinary; Antigen Presentation; Antigen-Presenting Cells; Clone Cells; | 2011 |
Characterization of drug-specific lymphocyte responses in a patient with drug-induced liver injury.
Topics: Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Huma | 2011 |
Anaphylaxis to trimethoprim: an under-appreciated risk in acute medical care.
Topics: Acute Disease; Aged; Anaphylaxis; Anti-Infective Agents, Urinary; Drug Hypersensitivity; Emergency T | 2004 |
Fatal adverse drug reaction to trimethoprim.
Topics: Aged; Anti-Infective Agents, Urinary; Drug Hypersensitivity; Fatal Outcome; Humans; Male; Stevens-Jo | 2005 |
Failure to stimulate antibodies in man after 7 days' high-dose treatment with rifampicin.
Topics: Antibodies; Drug Combinations; Drug Hypersensitivity; Female; Humans; Male; Rifampin; Trimethoprim | 1981 |
Co-trimoxazole toxicity.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Humans; Sulfamethoxazole; Trimethoprim; Trimethopri | 1984 |
Adverse reactions to trimethoprim-sulfamethoxazole in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; | 1984 |
Pneumocystis carinii pneumonia: a comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Child; Drug Combinations; Drug Eruption | 1984 |
Identification of the causative antigen in immune complex allergy. A simple method.
Topics: Antigens; Complement System Proteins; Drug Hypersensitivity; Female; Humans; Immune Complex Diseases | 1980 |
Aseptic meningitis as an adverse effect of co-trimoxazole.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Female; Humans; Meningitis; Meningitis, Aseptic; Su | 1983 |
The acquired immunodeficiency syndrome and a trimethoprim-sulfamethoxazole adverse reaction.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Hypersensitivity; Humans; Male; P | 1984 |
Lymphocyte transformation studies in suspected hypersensitivity to trimethoprim-sulphamethoxazole.
Topics: Adolescent; Adult; Aged; Child; Drug Hypersensitivity; Female; Humans; Lymphocyte Activation; Male; | 1983 |
Conjunctival photosensitivity to co-trimoxazole.
Topics: Conjunctival Diseases; Drug Combinations; Drug Hypersensitivity; Humans; Male; Middle Aged; Sulfamet | 1982 |
[Interstitial pneumonia caused by Sumetrolim allergy].
Topics: Child; Chronic Disease; Drug Hypersensitivity; Humans; Male; Pulmonary Fibrosis; Pyelonephritis; Tri | 1982 |
[Bone marrow aplasia induced by sulfamethoxazole-trimethoprim. Evidence of an allergic mechanism].
Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Pancytopenia; Sulfamethoxazole; Trimethoprim | 1981 |
[Acute immunoallergic thrombopenia due to sulfamethoxazole-trimethoprim].
Topics: Acute Disease; Drug Hypersensitivity; Humans; Sulfamethoxazole; Thrombocytopenia; Trimethoprim | 1980 |
Fine structural specificity differences of trimethoprim allergenic determinants.
Topics: Adolescent; Adult; Allergens; Drug Hypersensitivity; Epitope Mapping; Epitopes; Female; Humans; Midd | 1996 |
Trimethoprim/sulfamethoxazole incremental dose regimen in human immunodeficiency virus-infected persons.
Topics: Administration, Oral; Adult; CD4-Positive T-Lymphocytes; Dose-Response Relationship, Drug; Drug Admi | 1997 |
Adverse drug reactions in Sjögren's syndrome. Frequent allergic reactions and a specific trimethoprim-associated systemic reaction.
Topics: Adult; Aged; Antimalarials; Autoimmune Diseases; Drug Hypersensitivity; Female; Health Surveys; Huma | 1999 |
Anaphylaxis to trimethoprim.
Topics: Adult; Anaphylaxis; Drug Hypersensitivity; Histamine Release; Humans; Male; Skin Tests; Trimethoprim | 1999 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Surviva | 2000 |
Co-trimoxazole nephrotoxicity.
Topics: Acute Kidney Injury; Drug Combinations; Drug Hypersensitivity; Erythema; Humans; Kidney; Stevens-Joh | 1979 |
[Allergic-toxic agranulocytosis].
Topics: Abscess; Agranulocytosis; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Leukemia; | 1979 |
[Allergic vasculitis with arthritis due to bactrim allergy (author's transl)].
Topics: Aged; Arthritis; Blood Coagulation; Blood Platelets; Bronchitis; Drug Combinations; Drug Hypersensit | 1977 |
Co-trimoxazole induced angiitis presenting as acute renal failure. Report of a case.
Topics: Acute Kidney Injury; Adult; Diagnosis, Differential; Drug Combinations; Drug Hypersensitivity; Human | 1979 |
Stevens-Johnson syndrome (erythema multiforme) following ingestion of trimethoprim-sulfamethoxazole on two separate occasions in the same person: a case report.
Topics: Drug Combinations; Drug Hypersensitivity; Erythema Multiforme; Humans; Male; Middle Aged; Sulfametho | 1978 |
Hepatic injury in a child caused by trimethoprim-sulfamethoxazole.
Topics: Adolescent; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Combinations; Drug Hyp | 1978 |
[Generalized acute pustulosis. An unusual presentation of leukocytoclastic vasculitis].
Topics: Basement Membrane; Bronchitis; Complement C3; Drug Combinations; Drug Hypersensitivity; Female; Huma | 1978 |
[Adverse effects of treatment with sulfamethoxazole and trimethoprim. Report to the Adverse Drug Reaction Committee of the National Board of Health and Welfare].
Topics: Aged; Chemical and Drug Induced Liver Injury; Denmark; Drug Combinations; Drug Hypersensitivity; Fem | 1977 |
[Problems of ambulatory pharmacotherapy. 7. Report: combination of antibiotics, sulfanilamides and trimethoprim in monoinfections in ambulatory practice].
Topics: Ambulatory Care; Anti-Bacterial Agents; Bacterial Infections; Drug Combinations; Drug Hypersensitivi | 1976 |
Letter: Reaction to trimoxazole.
Topics: Aged; Drug Combinations; Drug Hypersensitivity; Humans; Male; Sulfamethoxazole; Trimethoprim | 1976 |
[Letter: Sulfamethoxazole-trimethoprim combination (cotrimoxazole). Unusual immuno-allergic reaction].
Topics: Blood Platelet Disorders; Drug Combinations; Drug Hypersensitivity; Drug Tolerance; Female; Humans; | 1975 |
[Letter: Acute iatrogenic colitis following clindamycin and various antibiotics].
Topics: Acute Disease; Anti-Bacterial Agents; Bone Diseases; Clindamycin; Colistin; Colitis; Drug Combinatio | 1975 |
[Pulmonary hypersensitive reactions].
Topics: Adolescent; Adult; Aged; Chlorpromazine; Drug Hypersensitivity; Humans; Lung Diseases; Methotrexate; | 1976 |
Demonstration of sensitized lymphocytes to trimethoprim/sulfamethoxazole and ofloxacin in a patient with cholestatic hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Hypersensitivity; Female; Humans; O | 1992 |
Allergy to sulfa drugs with postcoital urticaria.
Topics: Coitus; Drug Hypersensitivity; Female; Humans; Male; Prostatitis; Sulfamethoxazole; Trimethoprim; Ur | 1991 |
Trimethoprim-sulphonamide hypersensitivity in dogs.
Topics: Animals; Dog Diseases; Dogs; Drug Hypersensitivity; Joint Diseases; Male; Sulfonamides; Trimethoprim | 1990 |
Trimethoprim-sulphonamide hypersensitivity in dogs.
Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Drug Hypersensitivity; Female; Male; Sulfonamides; T | 1990 |
Hypersensitivity pneumonitis induced by trimethoprim.
Topics: Adult; Alveolitis, Extrinsic Allergic; Drug Hypersensitivity; Female; Humans; Trimethoprim | 1990 |
A localized hypersensitivity reaction to cotrimoxazole in a previously irradiated field simulating a recall phenomenon.
Topics: Drug Hypersensitivity; Humans; Skin; Trimethoprim | 1990 |
Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Desensitizat | 1989 |
Successful prophylaxis of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in AIDS patients with previous allergic reactions.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anti-Infective Agents; Cohort Studi | 1989 |
Death from drug-induced hemolytic anemia.
Topics: Aged; Anemia, Hemolytic; Cause of Death; Drug Combinations; Drug Hypersensitivity; Humans; Male; Sul | 1989 |
Reaction after re-exposure to trimethoprim-sulfamethoxazole.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Drug Hypersensitivity; Humans; Male; P | 1989 |
Therapy of pneumocystis carinii pneumonia after trimethoprim-sulfamethoxazole desensitization.
Topics: Acquired Immunodeficiency Syndrome; Adult; Combined Modality Therapy; Desensitization, Immunologic; | 1989 |
Adverse reactions to pyrimethamine-sulfadoxine in context of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Hypersensitivity; Humans; Pyrimethamine; | 1985 |
Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dermatitis, Exfoliative; Drug Combinations; Drug Hypersen | 1988 |
[Allergy to trimethoprim-sulfamethoxazole in normal, atopic and immunodepressed subjects].
Topics: Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate | 1987 |
[A case report of acquired immunodeficiency syndrome (AIDS) with hypersensitivity reactions to trimethoprim-sulfamethoxazole].
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Infective Agents; Drug Combinations; Drug Hypersensi | 1988 |
Trimethoprim-sulfamethoxazole desensitization in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Desensitization, Immunologic; Drug Hypersensitivity; Huma | 1988 |
Drugs as allergens. The molecular basis of IgE binding to trimethoprim.
Topics: Allergens; Drug Hypersensitivity; Haptens; Humans; Immunoglobulin E; Structure-Activity Relationship | 1988 |
Malpractice claim review. Pediatrics, urology.
Topics: Child; Drug Combinations; Drug Hypersensitivity; Humans; Male; Malpractice; Sulfamethoxazole; Trimet | 1987 |
Co-trimoxazole-induced hepatic injury--an analysis of cases with hypersensitivity-like reactions.
Topics: Adult; Aged; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug | 1987 |
[Immuno-allergic reactions to cotrimoxazole in a hospital population].
Topics: Anti-Infective Agents; Complement Activation; Drug Combinations; Drug Hypersensitivity; Hospitalizat | 1987 |
An immunoassay for the detection of IgE antibodies to trimethoprim in the sera of allergic patients.
Topics: Adult; Drug Combinations; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Radioimmunoassay; | 1987 |
Oral desensitization to trimethoprim-sulfamethoxazole in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Hypersensitivity; Humans; Male; Sulfamethoxazole; Tr | 1986 |
Successful treatment of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole in hypersensitive AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Diphenhydramine; Drug Combinations; Drug Hypersensitivity | 1985 |
[Cholestasis caused by co-trimoxazole. Presentation of a new patient and review of the literature].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Combinations; Drug Hyp | 1985 |
Sulfadiazine-induced allergy in six Doberman pinschers.
Topics: Animals; Arthritis; Dog Diseases; Dogs; Drug Hypersensitivity; Drug Therapy, Combination; Glomerulon | 1985 |
[Drug monitoring in the medical ward of a regional hospital].
Topics: Adult; Ampicillin; Anticoagulants; Antidepressive Agents; Central Nervous System Stimulants; Chemica | 1972 |
[Allergic reactons and composite drugs].
Topics: Adult; Anti-Infective Agents; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Female; Foli | 1971 |
The treatment of salmonellosis with trimethoprim-sulphamethoxazole and their combination with polymyxin B in adult patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Drug Combinations; Drug Hypersensitivity; Feces; Fem | 1973 |
[Drug hypersensitivity].
Topics: Aminopyrine; Anti-Bacterial Agents; Drug Hypersensitivity; Humans; Lymphocyte Activation; Sulfonamid | 1974 |
[Lymphocyte transformation test in drug hypersensitivity].
Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; | 1972 |
Problems in the treatment of venereal disease: bacterial resistance: allergy.
Topics: Drug Hypersensitivity; Gonorrhea; Humans; Kanamycin; Leucomycins; Male; Neisseria gonorrhoeae; Penic | 1972 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |
Extended therapy with a trimethoprim-sulphonamide for the treatment of established urinary tract infection.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Escherichi | 1971 |
Adverse effects of drugs commonly used in the treatment of urinary tract infection. A report from the Australian Drug Evaluation Committee.
Topics: Ampicillin; Anti-Infective Agents, Urinary; Australia; Chloramphenicol; Drug Hypersensitivity; Human | 1972 |