trimethoprim has been researched along with Agranulocytosis in 84 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients." | 9.06 | Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987) |
| "Fifty-six patients receiving remission induction treatment for acute leukemia were studied in a randomized trial comparing ciprofloxacin with trimethoprim-sulfamethoxazole plus colistin for prevention of infections." | 9.06 | Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. ( Dekker, AW; Rozenberg-Arska, M; Verhoef, J, 1987) |
| "Fifty-two patients with nonlymphocytic leukaemia were studied during remission induction treatment in a randomized trial to ascertain the effect of prophylactic oral trimethoprim-sulfamethoxazole on infection and fever rate." | 9.05 | Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia. ( Dekker, AW; Rozenberg-Arska, M; Sixma, JJ; Verhoef, J, 1981) |
| "The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days." | 7.67 | Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984) |
| "We report a case of prolonged fever, agranulocytosis, and anaemia associated with the long acting sulphametopyrazine-trimethoprim combination (Kelfiprim)." | 7.67 | Agranulocytosis and anaemia induced by sulfametopyrazine in a sulfametopyrazine-trimethoprim combination. ( Kueh, YK; Oh, VM; Teo, CP, 1989) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 7.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| "The amikacin-carbenicillin-cotrimoxazole combination was used as an empiric treatment for febrile episodes in patients with acute leukemia and severe granulocytopenia." | 7.66 | Empiric treatment of infections in granulocytopenic patients with acute leukemia: a study on amikacin-carbenicillin-cotrimoxazole. ( Cortelezzi, A; Penagini, R; Pogliani, EM; Radaelli, F, 1982) |
| "The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients." | 5.06 | Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987) |
| "Eighty-four cancer patients at risk of infection because of neutropenia were randomized to receive nalidixic acid as an alternative to trimethoprim-sulfamethoxazole (TMP-SMX) for infection prophylaxis." | 5.06 | Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration. ( Bow, EJ; Louie, TJ; Rayner, E; Scott, BA, 1987) |
| "Fifty-six patients receiving remission induction treatment for acute leukemia were studied in a randomized trial comparing ciprofloxacin with trimethoprim-sulfamethoxazole plus colistin for prevention of infections." | 5.06 | Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. ( Dekker, AW; Rozenberg-Arska, M; Verhoef, J, 1987) |
| "In an attempt to reduce the incidence of fever and infection, we randomized patients with cancer to receive trimethoprim/sulfamethoxazole plus erythromycin (TMP/SMX + E) versus placebos after each cycle of chemotherapy (no crossover) and to continue until granulocytopenia (polymorphonuclear leukocytes less than 500/mm3) resolved or the patient became febrile." | 5.05 | Oral antibiotic prophylaxis in patients with cancer: a double-blind randomized placebo-controlled trial. ( Edwards, BK; Johnson, A; Kramer, BS; Pizzo, PA; Robichaud, KJ; Schumaker, C, 1983) |
| "Of 545 patients expected to develop prolonged neutropenia and randomized to received trimethoprim-sulfamethoxazole (TMP-SMZ) or placebo, 342 were evaluable for occurrence of infection or bacteremia." | 5.05 | Trimethoprim-sulfamethoxazole in the prevention of infection in neutropenic patients. EORTC International Antimicrobial Therapy Project Group. ( , 1984) |
| "Fifty-two patients with nonlymphocytic leukaemia were studied during remission induction treatment in a randomized trial to ascertain the effect of prophylactic oral trimethoprim-sulfamethoxazole on infection and fever rate." | 5.05 | Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia. ( Dekker, AW; Rozenberg-Arska, M; Sixma, JJ; Verhoef, J, 1981) |
| "Sixty-two profoundly granulocytopenic patients with acute leukemia undergoing induction chemotherapy were prospectively randomized to receive either trimethoprim-sulfamethoxazole plus nystatin or nalidixic acid plus nystatin for prevention of infection." | 5.05 | Selective antimicrobial modulation as prophylaxis against infection during granulocytopenia: trimethoprim-sulfamethoxazole vs. nalidixic acid. ( Crowley, J; de Jongh, CA; Newman, KA; Schimpff, SC; Wade, JC; Wiernik, PH, 1983) |
| "The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days." | 3.67 | Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984) |
| "We report a case of prolonged fever, agranulocytosis, and anaemia associated with the long acting sulphametopyrazine-trimethoprim combination (Kelfiprim)." | 3.67 | Agranulocytosis and anaemia induced by sulfametopyrazine in a sulfametopyrazine-trimethoprim combination. ( Kueh, YK; Oh, VM; Teo, CP, 1989) |
| "6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine." | 3.67 | Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986) |
| "The amikacin-carbenicillin-cotrimoxazole combination was used as an empiric treatment for febrile episodes in patients with acute leukemia and severe granulocytopenia." | 3.66 | Empiric treatment of infections in granulocytopenic patients with acute leukemia: a study on amikacin-carbenicillin-cotrimoxazole. ( Cortelezzi, A; Penagini, R; Pogliani, EM; Radaelli, F, 1982) |
| "Norfloxacin has been compared to placebo (136 patients), sulfamethoxazole plus trimethoprim (SXT, 72 patients) and oral vancomycin plus colistin (V/C, 61 patients) for the prevention of alimentary tract-associated infections during and after induction chemotherapy." | 2.66 | The tolerability profile of prophylactic norfloxacin in neutropenic patients. ( Corrado, ML; Hesney, M; Struble, WE, 1988) |
| "Ketoconazole or miconazole was randomly administered to 42 and 46 neutropenic patients respectively." | 2.65 | Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. ( Cruciani, M; Klastersky, J; Meunier-Carpentier, F, 1983) |
| "Although the incidence of bacterial infections in the two groups was not statistically significantly different, almost twice as many bacterial infections were observed in the group that received the short course of empirical therapy." | 2.65 | Empirical antibacterial therapy in febrile, granulocytopenic bone marrow transplant patients. ( Goldman, AI; Kersey, J; McGlave, P; Peterson, PK; Ramsay, NK; Rhame, F, 1984) |
| " Initial protocol dosing achieved target plasma levels of trimethoprim (3 to 8 micrograms/ml) or gentamicin (4 to 10 micrograms/ml) in 57 of 68 (84 per cent) C-T/S trials compared to 21 of 60 (35 per cent) C-G trials." | 2.65 | Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. A prospective, randomized, double-blind study. ( Braine, HG; Fuller, DJ; Lietman, PS; Saral, R; Stuart, RK, 1980) |
| "The risks of agranulocytosis and aplastic anemia in relation to the use of anti-infective drugs were estimated in a population-based case-control study conducted in Europe and Israel." | 1.28 | Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study. ( , 1989) |
| "A seven-year-old boy presented with agranulocytosis after receiving cotrimoxazole for eight days." | 1.26 | [Agranulocytosis due to cotrimoxazole in a seven-year-old boy (author's transl)]. ( Lasson, U, 1977) |
| "Trimethoprim seems not to be a safe form of therapy in patients with a megaloblastic process; many of the toxic reactions reported with this drug may be on the basis of an unrecognized megaloblastic form of haemopoiesis." | 1.25 | Toxicity of trimethoprim-sulphamethoxazole in patients with megaloblastic haemopoiesis. ( Chanarin, I; England, JM, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (98.81) | 18.7374 |
| 1990's | 1 (1.19) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hargadon, MT | 1 |
| Young, VM | 1 |
| Schimpff, SC | 4 |
| Wade, JC | 3 |
| Minah, GE | 1 |
| Meunier-Carpentier, F | 2 |
| Cruciani, M | 1 |
| Klastersky, J | 2 |
| de Jongh, CA | 2 |
| Finley, RS | 2 |
| Joshi, JH | 2 |
| Aisner, J | 1 |
| Wiernik, PH | 2 |
| Principi, N | 1 |
| Marchisio, P | 1 |
| Biasini, A | 1 |
| Dalla Villa, A | 1 |
| Biasini, G | 1 |
| Pizzo, PA | 1 |
| Robichaud, KJ | 1 |
| Edwards, BK | 1 |
| Schumaker, C | 1 |
| Kramer, BS | 1 |
| Johnson, A | 1 |
| Riben, PD | 3 |
| Louie, TJ | 4 |
| Lank, BA | 2 |
| Kornachuk, E | 1 |
| Gurwith, MJ | 2 |
| Harding, GK | 3 |
| Ronald, AR | 4 |
| Zinner, SH | 1 |
| Bow, EJ | 2 |
| McNaughton, RD | 1 |
| Thompson, EI | 1 |
| Callihan, TR | 1 |
| Mauer, AM | 1 |
| Henry, SA | 1 |
| Peterson, PK | 1 |
| McGlave, P | 1 |
| Ramsay, NK | 1 |
| Rhame, F | 1 |
| Goldman, AI | 1 |
| Kersey, J | 1 |
| Gualtieri, RJ | 1 |
| Donowitz, GR | 1 |
| Kaiser, DL | 1 |
| Hess, CE | 1 |
| Sande, MA | 1 |
| Hendriks, WD | 1 |
| Sizoo, W | 1 |
| Löwenberg, B | 1 |
| Hagenbeek, A | 1 |
| Haaverstad, R | 1 |
| Kannelønning, KS | 1 |
| Dekker, AW | 2 |
| Rozenberg-Arska, M | 2 |
| Sixma, JJ | 1 |
| Verhoef, J | 2 |
| Mozzana, R | 1 |
| Cortelezzi, A | 2 |
| Radaelli, F | 2 |
| Polli, EE | 1 |
| Bakri, KM | 1 |
| Wasser, LP | 1 |
| Scaglione, C | 1 |
| Tormena, AM | 1 |
| Pavlovsky, S | 1 |
| Kauffman, CA | 1 |
| Liepman, MK | 1 |
| Bergman, AG | 1 |
| Mioduszewski, J | 1 |
| Newman, KA | 1 |
| Crowley, J | 1 |
| Beutler, SM | 1 |
| Barth, NM | 1 |
| Bayer, AS | 1 |
| Preisler, HD | 1 |
| Early, A | 1 |
| Hryniuk, W | 1 |
| Ekert, H | 1 |
| Jurk, IH | 1 |
| Waters, KD | 1 |
| Tiedemann, K | 1 |
| Lanzkowsky, P | 1 |
| Schaeffer, J | 1 |
| Penagini, R | 1 |
| Pogliani, EM | 1 |
| Stuart, RK | 1 |
| Braine, HG | 1 |
| Lietman, PS | 1 |
| Saral, R | 1 |
| Fuller, DJ | 1 |
| Bradley, PP | 1 |
| Warden, GD | 1 |
| Maxwell, JG | 1 |
| Rothstein, G | 1 |
| Siegenthaler, W | 1 |
| Fuchs, P | 1 |
| Lüthy, R | 1 |
| Rafecas, FJ | 1 |
| Sanz, MA | 1 |
| Balaguer, H | 1 |
| Santos, M | 1 |
| Besalduch, J | 1 |
| Martinez, J | 1 |
| Marty, ML | 1 |
| Gobernado, M | 1 |
| Malarme, M | 1 |
| Wilson, JM | 1 |
| Guiney, DG | 1 |
| Jacoby, GA | 1 |
| Kuntz, HD | 1 |
| Erbs, G | 1 |
| Thiel, H | 1 |
| Müller, FE | 1 |
| May, B | 1 |
| Guess, HA | 1 |
| Cohen, MS | 1 |
| Schimpff, S | 1 |
| Keränen, N | 1 |
| Kauko, M | 1 |
| Talvensaari, T | 1 |
| Veikkolin, T | 1 |
| Tiililä, M | 1 |
| Ward, TT | 1 |
| Thomas, RG | 1 |
| Fye, CL | 1 |
| Arbeit, R | 1 |
| Coltman, CA | 1 |
| Craig, W | 1 |
| Dana, BW | 1 |
| Finegold, SM | 1 |
| Lentino, J | 1 |
| Penn, RL | 1 |
| Kunz, HD | 1 |
| Brunton, JL | 1 |
| Marty, M | 1 |
| Gisselbrecht, C | 1 |
| Samson-Lepors, MJ | 1 |
| Masera, G | 1 |
| Baronciani, D | 1 |
| Conti, A | 1 |
| Jankovic, M | 1 |
| Uderzo, C | 1 |
| Lawson, DH | 1 |
| Henry, DA | 1 |
| Inman, WH | 1 |
| Lasson, U | 1 |
| Melikian, V | 1 |
| Falk, R | 1 |
| Ceri, J | 1 |
| Bratić-Mikes, V | 1 |
| Stefanović, N | 1 |
| Mikes, A | 1 |
| Teo, CP | 1 |
| Oh, VM | 1 |
| Kueh, YK | 1 |
| Gava, R | 1 |
| Carli, M | 1 |
| Chastagner, P | 1 |
| Hartmann, O | 1 |
| Tancrede, C | 1 |
| Kalifa, C | 1 |
| Patte, C | 1 |
| Flamant, F | 1 |
| Lemerle, J | 1 |
| Bartoloni, A | 1 |
| Fanci, R | 1 |
| Orsi, A | 1 |
| Aquilini, D | 1 |
| Bosi, A | 1 |
| Rossi Ferrini, P | 1 |
| Paradisi, F | 1 |
| Hatton, CS | 1 |
| Peto, TE | 1 |
| Bunch, C | 1 |
| Pasvol, G | 1 |
| Russell, SJ | 1 |
| Singer, CR | 1 |
| Edwards, G | 1 |
| Winstanley, P | 1 |
| Koletzko, B | 1 |
| Wendel, U | 1 |
| Bremer, HJ | 1 |
| Winston, DJ | 1 |
| Ho, WG | 1 |
| Champlin, RE | 1 |
| Karp, J | 1 |
| Bartlett, J | 1 |
| Talbot, G | 1 |
| Levitt, L | 1 |
| Deresinski, S | 1 |
| Funada, H | 1 |
| Otis, LL | 1 |
| Terezhalmy, GT | 1 |
| Corrado, ML | 1 |
| Struble, WE | 1 |
| Hesney, M | 1 |
| Rayner, E | 1 |
| Scott, BA | 1 |
| Wells, CL | 1 |
| Ferrieri, P | 1 |
| Weisdorf, DJ | 1 |
| Rhame, FS | 1 |
| Harris, GJ | 1 |
| Franson, TR | 1 |
| Linares, M | 1 |
| García, S | 1 |
| Colomina, P | 1 |
| Miguel-Borja, JM | 1 |
| Riou, B | 1 |
| Richard, C | 1 |
| Rimailho, A | 1 |
| Auzepy, P | 1 |
| Magyar, T | 1 |
| Graber, H | 1 |
| Arr, M | 1 |
| Csiba, A | 1 |
| Kelemen, E | 1 |
| Péterfy, M | 1 |
| Jánossa, M | 1 |
| Buchanan, AG | 1 |
| Rayner, EN | 1 |
| Parker, SE | 1 |
| van der Waaij, D | 1 |
| Spiers, AS | 1 |
| Tattersall, MH | 1 |
| Gaya, H | 1 |
| Frisch, JM | 1 |
| Lagarde, B | 1 |
| Varieras, B | 1 |
| Casey, TP | 1 |
| Matthews, JR | 1 |
| Buchanan, JG | 1 |
| Herbert, V | 1 |
| Lewin, EB | 1 |
| Klein, JO | 1 |
| Finland, M | 1 |
| Williamson, GD | 1 |
| Crowe, GR | 1 |
| Pines, A | 1 |
| Schmid, F | 1 |
| Haus, E | 1 |
| Schreiber, A | 1 |
| Stamps, TJ | 1 |
| Wicks, AC | 1 |
| Chanarin, I | 1 |
| England, JM | 1 |
| Destaing, F | 1 |
| Villand, J | 1 |
| Carli, H | 1 |
| Carli, PM | 1 |
| Martin, F | 1 |
| Klepping, C | 1 |
| Palva, IP | 1 |
| Koivisto, O | 1 |
6 reviews available for trimethoprim and Agranulocytosis
| Article | Year |
|---|---|
Prophylaxis in severe granulocytopenia.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Clinical Trials as | 1984 |
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of bacterial infections in granulocytopenic patients.
Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topi | 1984 |
[Bacteriologic management of patients with decreased resistance].
Topics: Agranulocytosis; Anti-Bacterial Agents; Antisepsis; Bacterial Infections; Drug Combinations; Humans; | 1984 |
[Co-trimoxazole chemoprophylaxis in immunocompromised patients: analysis of the literature].
Topics: Adult; Agranulocytosis; Anti-Infective Agents; Bacterial Infections; Child; Drug Combinations; Human | 1989 |
[Prophylactic administration of antimicrobiological agents and reflection thereon--prevention of infections in hematologic diseases and malignancies].
Topics: Agranulocytosis; Drug Combinations; Hematologic Diseases; Humans; Infection Control; Neoplasms; Pati | 1986 |
Trimethoprim-sulfamethoxazole. Metabolism of folic acid in man.
Topics: Agranulocytosis; Aminobenzoates; Anemia; Bile; Biological Transport, Active; Bone Marrow; Bone Marro | 1973 |
27 trials available for trimethoprim and Agranulocytosis
| Article | Year |
|---|---|
Selective suppression of alimentary tract microbial flora as prophylaxis during granulocytopenia.
Topics: Agranulocytosis; Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Carcinoma, Small Cell; D | 1981 |
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Keto | 1983 |
Trimethoprim/sulfamethoxazole versus placebo: a double-blind comparison of infection prophylaxis in patients with small cell carcinoma of the lung.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; | 1983 |
Oral antibiotic prophylaxis in patients with cancer: a double-blind randomized placebo-controlled trial.
Topics: Adolescent; Adult; Agranulocytosis; Bacterial Infections; Child; Child, Preschool; Clinical Trials a | 1983 |
Reduction in mortality from gram-negative sepsis in neutropenic patients receiving trimethoprim/sulfamethoxazole therapy.
Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Female; Humans; Leukem | 1983 |
Prophylaxis of bacterial infections with oral antibiotics in neutropenic patients. Lessons from the last two EORTC trials and prospects for the future.
Topics: Administration, Oral; Agranulocytosis; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; | 1983 |
Randomized controlled trial comparing trimethoprim/sulfamethoxazole and trimethoprim for infection prophylaxis in hospitalized granulocytopenic patients.
Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; | 1984 |
Prophylaxis in severe granulocytopenia.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Clinical Trials as | 1984 |
Symposium on infectious complications of neoplastic disease (Part II). Chemoprophylaxis of bacterial infections in granulocytopenic patients.
Topics: Acute Disease; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topi | 1984 |
Trimethoprim-sulfamethoxazole in the prevention of infection in neutropenic patients. EORTC International Antimicrobial Therapy Project Group.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Drug Combina | 1984 |
Empirical antibacterial therapy in febrile, granulocytopenic bone marrow transplant patients.
Topics: Adolescent; Adult; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transpl | 1984 |
Double-blind randomized study of prophylactic trimethoprim/sulfamethoxazole in granulocytopenic patients with hematologic malignancies.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Clinical Trials as Topic; Double-Blind Method; Drug Therap | 1983 |
Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia.
Topics: Acute Disease; Agranulocytosis; Amphotericin B; Drug Combinations; Drug Therapy, Combination; Fever; | 1981 |
[Prophylactic controlled trials with cotrimoxazole in afebrile neutropenic patients with malignant hemopathies].
Topics: Adult; Agranulocytosis; Child; Clinical Trials as Topic; Drug Combinations; Fever; Humans; Infection | 1982 |
Trimethoprim/sulfamethoxazole prophylaxis in neutropenic patients. Reduction of infections and effect on bacterial and fungal flora.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Drug Resistance | 1983 |
Selective antimicrobial modulation as prophylaxis against infection during granulocytopenia: trimethoprim-sulfamethoxazole vs. nalidixic acid.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Child; Drug Combinations; Female; Hu | 1983 |
Prophylactic co-trimoxazole and lactobacilli preparation in neutropenic patients.
Topics: Agranulocytosis; Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Biological Products | 1980 |
Carbenicillin-trimethoprim/sulfamethoxazole versus carbenicillin-gentamicin as empiric therapy of infection in granulocytopenic patients. A prospective, randomized, double-blind study.
Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Carbenicillin; Clinical Trials as Topic; Double- | 1980 |
[Carbenicillin-trimethoprim/sulphamethoxazole or carbenicillin-tobramycin as empirical treatment of infection in granulocytopenic patients. A controlled prospective trial (author's transl)].
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Clinical Trials as Topi | 1981 |
Vancomycin plus gentamicin and cotrimoxazole for prevention of infections in neutropenic cancer patients (a comparative, placebo-controlled pilot study).
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Clinical | 1981 |
Trimethoprim-sulfamethoxazole prophylaxis in granulocytopenic patients with acute leukemia: evaluation of serum antibiotic levels in a randomized, double-blind, placebo-controlled Department of Veterans Affairs Cooperative Study.
Topics: Acute Disease; Adult; Agranulocytosis; Bacterial Infections; Double-Blind Method; Female; Humans; Le | 1993 |
A prospective controlled investigation of prophylactic trimethoprim/sulfamethoxazole in hospitalized granulocytopenic patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacteriological Tech | 1979 |
The influence of ofloxacin versus trimethoprim-sulfamethoxazole on the aerobic flora in granulocytopenic subjects.
Topics: Adult; Aged; Agranulocytosis; Bacteria, Aerobic; Drug Combinations; Female; Humans; Intestines; Leuk | 1989 |
Norfloxacin for prevention of bacterial infections in granulocytopenic patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Drug Combinations; Drug Therapy, Com | 1987 |
The tolerability profile of prophylactic norfloxacin in neutropenic patients.
Topics: Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Colistin; Diarrhea; Gastrointestina | 1988 |
Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration.
Topics: Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dr | 1987 |
Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin.
Topics: Acute Disease; Agranulocytosis; Bacterial Infections; Ciprofloxacin; Colistin; Drug Combinations; Dr | 1987 |
53 other studies available for trimethoprim and Agranulocytosis
| Article | Year |
|---|---|
Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole).
Topics: Agranulocytosis; Amoxicillin; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; | 1984 |
[Fatal agranulocytosis and toxic liver damage after use of trimethoprim-sulfamethoxazole].
Topics: Aged; Agranulocytosis; Drug Combinations; Female; Humans; Liver; Sepsis; Sulfamethoxazole; Trimethop | 1984 |
Efficacy of the tobramycin - cotrimoxazole - cephalothin combination for febrile episodes in leukemic patients with granulocytopenia.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Cephalothin; Child; Drug Combinatio | 1981 |
Trimethoprim-sulfamethoxazole and granulocytopenia.
Topics: Agranulocytosis; Humans; Infection Control; Sulfamethoxazole; Trimethoprim | 1982 |
Preventing infection in neutropenic cancer patients.
Topics: Agranulocytosis; Bacterial Infections; Humans; Immunosuppression Therapy; Leukemia; Neutropenia; Sul | 1983 |
Prevention of infection and bleeding in leukemic patients receiving intensive remission maintenance therapy.
Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Drug Combinations; Female | 1981 |
Prophylactic use of TMP-SMZ in leukemia.
Topics: Agranulocytosis; Child; Drug Combinations; Humans; Leukemia, Lymphoid; Neutropenia; Pulmonary Fibros | 1982 |
Empiric treatment of infections in granulocytopenic patients with acute leukemia: a study on amikacin-carbenicillin-cotrimoxazole.
Topics: Acute Disease; Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial | 1982 |
Neutropenia and thrombocytopenia in renal allograft recipients treated with trimethoprim-sulfamethoxazole.
Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Drug Combinations; Drug Synergism; Humans; Kidney | 1980 |
[Prevention of bacterial infections].
Topics: Agranulocytosis; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Endocarditis; | 1981 |
Failure of oral trimethoprim-sulfamethoxazole prophylaxis in acute leukemia: isolation of resistant plasmids from strains of Enterobacteriaceae causing bacteremia.
Topics: Acute Disease; Adult; Agranulocytosis; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterobact | 1982 |
Perils of prophylaxis.
Topics: Agranulocytosis; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Drug Resistance, Mi | 1982 |
[Hematologic and dermatologic side-effects of antibiotic therapy].
Topics: Aged; Agranulocytosis; Drug Combinations; Epidermolysis Bullosa; Female; Humans; Middle Aged; Sulfam | 1982 |
Drug treatment of otitis media and urinary tract infections.
Topics: Agranulocytosis; Child; Humans; Neutropenia; Otitis Media; Sulfamethoxazole; Thrombocytopenia; Trime | 1982 |
Intravenous sulfamethoxazole-trimethoprim plus ticarcillin as empiric antibiotic therapy for granulocytopenic patient.
Topics: Agranulocytosis; Bacterial Infections; Drug Therapy, Combination; Humans; Sulfamethoxazole; Trimetho | 1981 |
Antimicrobial prophylaxis and treatment in patients with granulocytopenia.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Humans; Sulfamethox | 1981 |
[Drug induced agranulocytosis].
Topics: Agranulocytosis; Dipyrone; Humans; Male; Middle Aged; Oxyphenbutazone; Sulfamethoxazole; Trimethopri | 1981 |
Infection prevention during profound granulocytopenia. New approaches to alimentary canal microbial suppression.
Topics: Agranulocytosis; Air Microbiology; Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Dru | 1980 |
[Allergic-toxic agranulocytosis].
Topics: Abscess; Agranulocytosis; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Leukemia; | 1979 |
[Treatment of febrile episodes in the neutropenic subject: use of the combination of amikacin-colistin-trimethoprim-sulphamethoxazole].
Topics: Agranulocytosis; Amikacin; Colistin; Drug Therapy, Combination; Fever; Humans; Kanamycin; Neutropeni | 1979 |
[Hemopathies caused by drugs in children: aplastic anemia, agranulocytosis, megaloblastic anemia].
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; | 1978 |
Fatal agranulocytosis attributed to co-trimoxazole therapy.
Topics: Agranulocytosis; Humans; Sulfamethoxazole; Trimethoprim | 1977 |
Fatal agranulocytosis attributed to co-trimoxazole therapy.
Topics: Agranulocytosis; Humans; Sulfamethoxazole; Trimethoprim | 1977 |
[Agranulocytosis due to cotrimoxazole in a seven-year-old boy (author's transl)].
Topics: Agranulocytosis; Child; Drug Combinations; Humans; Male; Respiratory Tract Infections; Sulfamethoxaz | 1977 |
Treatment of febrile episodes in neutropenic patients.
Topics: Agranulocytosis; Anti-Bacterial Agents; Clindamycin; Drug Combinations; Fever; Humans; Immunosuppres | 1976 |
[2 cases of fatal iatrogenic agranulocytosis most likely caused by a sulfamethoxazole/trimethoprim combination].
Topics: Adult; Agranulocytosis; Drug Combinations; Female; Humans; Middle Aged; Sulfamethoxazole; Trimethopr | 1976 |
Agranulocytosis and anaemia induced by sulfametopyrazine in a sulfametopyrazine-trimethoprim combination.
Topics: Adult; Agranulocytosis; Anemia; Antigens, Viral; Capsid Proteins; Cystitis; Drug Combinations; Femal | 1989 |
Role of parenteral antibiotherapy in gastrointestinal tract flora suppression. A study in children treated with high-dose chemotherapy and autologous bone marrow transplantation.
Topics: Adolescent; Agranulocytosis; Bone Marrow Transplantation; Cefotaxime; Child; Child, Preschool; Diges | 1989 |
Anti-infective drug use in relation to the risk of agranulocytosis and aplastic anemia. A report from the International Agranulocytosis and Aplastic Anemia Study.
Topics: Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Anti-Infective Agents; Drug Combinations; | 1989 |
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
Topics: Acute Disease; Adult; Agranulocytosis; Amodiaquine; Drug Combinations; Drug Therapy, Combination; Fe | 1986 |
Lithium for treatment of neutropenia in glycogen storage disease type Ib.
Topics: Agranulocytosis; Chlorides; Drug Combinations; Drug Therapy, Combination; Female; Glycogen Storage D | 1986 |
The granulocytopenic patient: another consideration for antimicrobial prophylaxis.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Dental Care for Disabled; Humans; Mout | 1985 |
[Cotrimoxazole-induced agranulocytosis].
Topics: Agranulocytosis; Anti-Infective Agents; Drug Combinations; Humans; Sulfamethoxazole; Trimethoprim; T | 1988 |
The importance of surveillance stool cultures during periods of severe neutropenia.
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Bone Marrow Transplantation; Child; Drug Combinations | 1987 |
Neutropenia induced by short-term oral trimethoprim-sulfamethoxazole therapy; case report.
Topics: Adult; Agranulocytosis; Anti-Infective Agents, Urinary; Drug Combinations; Female; Humans; Neutropen | 1986 |
[Cotrimoxazole-induced agranulocytosis].
Topics: Aged; Agranulocytosis; Anti-Infective Agents, Urinary; Drug Combinations; Female; Humans; Sulfametho | 1987 |
Potential risks of trimethoprim-sulfamethoxazole prophylaxis in neutropenic patients.
Topics: Agranulocytosis; Drug Combinations; Drug Resistance, Microbial; Humans; Neutropenia; Risk; Sulfameth | 1985 |
[Treatment of infections in granulocytopenia patients with a brulamycin-bactrim combination].
Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Drug Combinations; Drug Therapy, Combination; Fe | 1985 |
Nystatin prophylaxis of fungal colonization and infection in granulocytopenic patients: correlation of colonization and clinical outcome.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Drug Combinations; Female; Fever; H | 1985 |
[Limitations of selective decontamination of the digestive system in granulopenia patients toward the prevention of infection].
Topics: Agranulocytosis; Digestive System; Disinfection; Drug Combinations; Drug Resistance, Microbial; Huma | 1985 |
Editorial: Co-trimoxazole and blood.
Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Bone Marrow; Drug Combinations; Female; Folic | 1973 |
Indications for systemic antibiotic prophylaxis in neutropenic patients.
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot | 1974 |
Clinical experience with adverse reactions to trimethoprim-sulfamethoxazole.
Topics: Aged; Agranulocytosis; Anemia, Aplastic; Anemia, Macrocytic; Child; Depression; Drug Combinations; D | 1973 |
[Transitory agranulocytosis of toxic origin in a child (during treatment with oxyphenylbutazone and sulfamethoxazole-trimethoprim)].
Topics: Agranulocytosis; Child, Preschool; Drug Therapy, Combination; Erythromycin; Fever; Humans; Male; Oxy | 1974 |
Adverse haematological effects and trimethoprim-sulphamethoxazole administration.
Topics: Aged; Agranulocytosis; Anemia; Child; Drug Combinations; Female; Hematologic Diseases; Humans; Male; | 1973 |
Trimethoprim-sulfamethoxazole: absorption, excretion, and toxicity in six children.
Topics: Agranulocytosis; Bacterial Infections; Carrier State; Child; Dose-Response Relationship, Drug; Drug | 1973 |
Trimethoprim-sulphamethoxazole mixtures and agranulocytosis.
Topics: Agranulocytosis; Anti-Infective Agents; Ear Diseases; Folic Acid Antagonists; Humans; Infant; Male; | 1972 |
Co-trimoxazole in prevention of purulent exacerbations of chronic bronchitis.
Topics: Adult; Aged; Agranulocytosis; Anti-Infective Agents; Bronchitis; Chronic Disease; Drug Combinations; | 1973 |
[Antibiotic therapy--conclusion. 5. Sulfonamides, trimethoprim].
Topics: Agranulocytosis; Bacterial Infections; Colitis; Cyanosis; Gastrointestinal Diseases; Humans; Psychos | 1973 |
Trimethoprim-sulphamethoxazole in typhoid fever.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Infective Agents; Child; Child, Preschool; Folic Acid | 1972 |
Toxicity of trimethoprim-sulphamethoxazole in patients with megaloblastic haemopoiesis.
Topics: Adult; Aged; Agranulocytosis; Anemia, Macrocytic; Anemia, Pernicious; Anti-Infective Agents; Arthrit | 1972 |
[Transient agranulocytosis in the course of treatment with sulfamethoxazole-trimethoprim].
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Anti-Infective Agents; Bone Marrow; Bon | 1972 |
Agranulocytosis associated with trimethoprim-sulphamethoxazole.
Topics: Aged; Agranulocytosis; Anti-Infective Agents; Female; Folic Acid Antagonists; Humans; Middle Aged; P | 1971 |