trimethoprim has been researched along with Abnormalities, Autosome in 11 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A sever Pneumocystis carinii pneumonitis developed, but was successfully treated with pentamidine, sulfametoxazole with trimetoprim and transfer factor." | 1.26 | Indication of primary immune deficiency in Fanconi's anemia. ( Hertz, H; Lundsteen, C; Pedersen, FK; Platz, P; Thomsen, M, 1977) |
| "Human diploid fibroblasts cultured in Dulbecco's Modified Eagle's medium (DME) were exposed to different concentrations of 15 antibiotics to determine the limiting toxic concentration." | 1.25 | Toxicity of antibiotics on cultured human skin fibroblasts. ( Byarugaba, W; Koske-Westphal, T; Passarge, E; Rüdiger, HW; Wöhler, W, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abou-Eisha, A | 1 |
| Lentze, MJ | 1 |
| Sørensen, PJ | 1 |
| Jensen, MK | 1 |
| Pedersen, FK | 1 |
| Hertz, H | 1 |
| Lundsteen, C | 1 |
| Platz, P | 1 |
| Thomsen, M | 1 |
| Bennett, PM | 1 |
| Richmond, MH | 1 |
| Gebhart, E | 3 |
| Byarugaba, W | 1 |
| Rüdiger, HW | 1 |
| Koske-Westphal, T | 1 |
| Wöhler, W | 1 |
| Passarge, E | 1 |
| Salter, AJ | 1 |
| Stevenson, AC | 1 |
| Clarke, G | 1 |
| Patel, CR | 1 |
| Hughes, DT | 1 |
11 other studies available for trimethoprim and Abnormalities, Autosome
| Article | Year |
|---|---|
Evaluation of cytogenetic and DNA damage induced by the antibacterial drug, trimethoprim.
Topics: Anti-Infective Agents, Urinary; Chromosome Aberrations; Chromosome Breakage; Comet Assay; DNA Damage | 2006 |
[Useful and superfluous measures in the treatment of infant diarrhea].
Topics: Bacterial Infections; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Diarrhea; Diar | 1982 |
Cytogenetic studies in patients treated with trimethoprim-sulfamethoxazole.
Topics: Bone Marrow Cells; Cell Nucleus; Chromosome Aberrations; Drug Combinations; Female; Humans; Male; Mu | 1981 |
Indication of primary immune deficiency in Fanconi's anemia.
Topics: Abnormalities, Multiple; Adrenal Cortex Hormones; Androgens; Anemia, Aplastic; Child; Chromosome Abe | 1977 |
Translocation of a discrete piece of deoxyribonucleic acid carrying an amp gene between replicons in Eschericha coli.
Topics: Ampicillin; Carbenicillin; Chromosome Aberrations; DNA, Bacterial; DNA, Circular; Escherichia coli; | 1976 |
[Chromosome studies in children treated with bactrim (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Chromosome Aberrations; Drug Combinations; Female; Humans; Lymp | 1975 |
Toxicity of antibiotics on cultured human skin fibroblasts.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cell Survival; Cells, Cultured; Cephalothin; Chloramphenicol | 1975 |
Proceedings: Chromosomal studies in Bactrim therapy.
Topics: Chromosome Aberrations; Drug Combinations; Sulfamethoxazole; Trimethoprim | 1975 |
The toxicity profile of trimethoprim-sulphamethoxazole after four years of widespread use.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Anti-Infective Agents; Child; Child, Presch | 1973 |
Chromosomal studies in vivo and in vitro of trimethoprim and sulphamethoxazole (co-trimoxazole).
Topics: Aged; Anti-Infective Agents; Cell Division; Cells, Cultured; Chromatids; Chromosome Aberrations; Chr | 1973 |
[Studies on chromosomes in Bactrim therapy].
Topics: Adolescent; Adult; Anti-Infective Agents; Chromosome Aberrations; Drug Combinations; Female; Folic A | 1973 |