trimethoprim--sulfamethoxazole-drug-combination and Ulcer

We describe the first case of chancroid seen in the Czech Republic, diagnosed in a 40-year-old heterosexual HIV-positive man. Despite genital localization of the ulcer, the transmission of Haemophilus ducreyi infection in our patient remains unclear, as he denied having sexual intercourse and he did not travel outside the Czech Republic for several months before the ulcer appeared. The correct diagnosis has been revealed by a multiplex nucleic acid amplification test. Physicians in countries in the eastern and central Europe region should be aware that chancroid can occur in their patients.

Topics: Adult; Azithromycin; Chancroid; Haemophilus ducreyi; HIV Seropositivity; Humans; Lymphadenopathy; Male; Methicillin-Resistant Staphylococcus aureus; Multiplex Polymerase Chain Reaction; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Basidiobolomycosis is an uncommon chronic deep fungal infection in which gradually enlarging granulomas form, usually in the subcutaneous fat tissues of the limbs, chest or trunk of immunocompetent hosts, primarily children and young adults. It is caused by the fungus. None declared.

Topics: Child, Preschool; Combined Modality Therapy; Entomophthorales; Female; Humans; Itraconazole; Potassium Iodide; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer; Zygomycosis

Granuloma inguinale, or Donovanosis, is a rare, sexually transmitted ulcerative disease primarily affecting the genital area. In this report, we present a case of a 50-year-old man that was diagnosed with granuloma inguinale after a 2-month history of a penile ulcer. Histological analysis demonstrated the presence of Donovan bodies within macrophages, confirming the diagnosis. He was subsequently treated with trimethoprim/sulfamethoxazole with improvement in the ulcer. This case serves as a reminder to clinicians that although granuloma inguinale is rarely encountered in the US, it should still be suspected in patients with non-healing penile ulcers.

Topics: Anti-Bacterial Agents; Granuloma Inguinale; Humans; Male; Middle Aged; Penile Diseases; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Doxycycline; Erythromycin; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Lymphogranuloma Venereum; Male; Pregnancy; Pregnancy Complications, Infectious; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Chemistry Tests; Clonixin; Colic; Esophageal Diseases; Esophageal Perforation; Fatal Outcome; Horse Diseases; Horses; Male; Metronidazole; Pleurisy; Thorax; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer; Ultrasonography

Topics: Adult; Anti-Infective Agents, Urinary; Drug Therapy, Combination; Female; Humans; Metronidazole; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer; Vulva; Vulvar Diseases

Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Female; Humans; Male; Penile Diseases; Serologic Tests; Sex Work; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Topics: Adolescent; Drug Combinations; Esophageal Diseases; Hiccup; Humans; Male; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Female; Humans; Male; Penile Diseases; Serologic Tests; Sex Work; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer