trimethoprim--sulfamethoxazole-drug-combination and Neural-Tube-Defects

Nocardiosis is an infection caused by a soil-borne aerobic micro-organism. The pathogen is most commonly introduced in humans by inhalation into the respiratory tract. This infection may be transient and subclinical or may result in an acute or chronic bronchopulmonary process. Although an unusual cause of pulmonary infection in immunocompentent individuals, human nocardiosis is now documented more often in patients whose cell-mediated immunity is compromised by immunosuppression from comorbid disease or as a result of modern medical intervention. The diagnosis is often elusive unless a high index of suspicion is maintained. We present a patient with localized pulmonary nocardiosis who was immunosuppressed by virtue of a myeloproliferative disorder.

Topics: Aged; Anti-Infective Agents; Biopsy, Needle; Bronchoscopy; Follow-Up Studies; Humans; Immunocompromised Host; Lung; Lung Diseases; Male; Neural Tube Defects; Nocardia asteroides; Nocardia Infections; Primary Myelofibrosis; Radiography, Thoracic; Solitary Pulmonary Nodule; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Female; Humans; Neural Tube Defects; Pregnancy; Trimethoprim, Sulfamethoxazole Drug Combination; Vitamins