trimethoprim--sulfamethoxazole-drug-combination and Nephrosis--Lipoid

Strongyloidiasis is caused by a small intestinal nematode with a complex life cycle. In Italy the infection is endemic in rural areas of the Po Valley. The clinical syndrome of S. stercoralis encompasses a broad spectrum of symptoms and signs and, in the immunocompromised host, larvae can migrate to different organs and tissues. Also immune response seems to play a role in the pathogenesis of the disease. We report a case of strongyloidiasis complicated by Gram-negative sepsis and nephrotic syndrome in an immigrant from South America with a normal immune response. Whereas sepsis cleared up quickly, parasitic clearance was obtained only after treatment with ivermectin and nephrotic syndrome was still present three months after the end of treatment.

Topics: Adult; Albendazole; Animals; Anthelmintics; Anti-Bacterial Agents; Bacteremia; Ecuador; Endemic Diseases; Escherichia coli Infections; Humans; Immunocompetence; Italy; Ivermectin; Larva; Male; Nephrosis, Lipoid; Nephrotic Syndrome; Prednisone; Strongyloides stercoralis; Strongyloidiasis; Trimethoprim, Sulfamethoxazole Drug Combination