trimethoprim--sulfamethoxazole-drug-combination and Macrophage-Activation-Syndrome

Topics: Abdominal Abscess; Adult; Anti-Bacterial Agents; Bone Marrow; Humans; Macrophage Activation; Macrophage Activation Syndrome; Osteitis; Pubic Symphysis; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Wound Infection

We report the case of a patient with disseminated toxoplasmosis who presented with cervical lymphadenopathies and pneumonia. Although the infection was successfully treated with co-trimoxazole, the patient developed reactive macrophage activation syndrome (rMAS). To our knowledge, this is the first reported case of rMAS triggered by toxoplasmosis in the medical literature.

Topics: Anti-Infective Agents; Female; Humans; Lymphatic Diseases; Macrophage Activation Syndrome; Middle Aged; Neck; Pneumonia; Toxoplasmosis; Trimethoprim, Sulfamethoxazole Drug Combination