trimethoprim--sulfamethoxazole-drug-combination and Hand-Dermatoses

Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Infections; Cephalexin; Ciprofloxacin; Clindamycin; Hand; Hand Dermatoses; Humans; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Abscess; Adult; Anti-Bacterial Agents; Cellulitis; Ciprofloxacin; Drug Therapy, Combination; Exudates and Transudates; Hand Dermatoses; Hand Injuries; Humans; Immunocompetence; Male; Recurrence; Serratia Infections; Serratia marcescens; Trimethoprim, Sulfamethoxazole Drug Combination; Wound Infection; Wounds, Penetrating

Topics: Aged; Anti-Bacterial Agents; Drug Eruptions; Hand Dermatoses; Humans; Male; Recurrence; Skin Ulcer; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Amputation, Surgical; Animals; Anti-Bacterial Agents; Delayed Diagnosis; Disease Susceptibility; Fingers; Fishes; Hand Dermatoses; Humans; Levofloxacin; Male; Middle Aged; Mycobacterium Infections, Nontuberculous; Mycobacterium marinum; Pneumonia; Postoperative Complications; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Adult; Anti-Infective Agents; Diagnosis, Differential; Female; Fingers; Hand Dermatoses; Humans; Mycetoma; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Adult; Anti-Infective Agents; Blister; Diagnosis, Differential; Drug Eruptions; Fingers; Hand Dermatoses; Humans; Male; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Adolescent; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antifungal Agents; Blood Sedimentation; Female; Fluconazole; Foot Dermatoses; Hand Dermatoses; Hepatomegaly; Herpes Zoster; HIV Infections; Humans; Hypergammaglobulinemia; Immunocompromised Host; Onychomycosis; Tinea; Trimethoprim, Sulfamethoxazole Drug Combination

A total of 105 patients with established fixed drug eruption (FDE) by oral provocation were evaluated with regard to a drug-related site involvement. Cotrimoxazole was the leading causative agent (63.8%), followed by naproxen sodium (23.8%), dipyrone (5.7%), oxicams (4.8%) and other rare causes (1.9%). Cotrimoxazole most frequently induced lesions on genital mucosa; naproxen and oxicams on lips; and dipyrone on trunk and extremities. Isolated FDE on male genitalia (n = 16) was exclusively because of cotrimoxazole. A highly significant association could be established between naproxen and FDE on lips (chi-square = 28.3; corrected P =.000002). As this study represents the largest series of patients with naproxen-induced FDE, we would suggest that naproxen should be considered as an important potential cause of FDE on lips.

Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dipyrone; Drug Eruptions; Facial Dermatoses; Female; Foot Dermatoses; Genital Diseases, Male; Hand Dermatoses; Humans; Lip Diseases; Male; Middle Aged; Naproxen; Trimethoprim, Sulfamethoxazole Drug Combination

A case of bilateral, symmetric, sporothricoid granulomas involving the dorsa of fingers and wrists is reported. The culture-proved Mycobacterium marinum skin infection was acquired by a fish-fancier while clearing his aquarium with bare hands. The patient suffered from chronic hand eczema. Treatment with co-trimoxazole was successful.

Topics: Adult; Hand Dermatoses; Humans; Male; Mycobacterium Infections, Nontuberculous; Sporotrichosis; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Adult; Hand Dermatoses; Humans; Male; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Swimming Pools; Trimethoprim, Sulfamethoxazole Drug Combination; Water Microbiology

A 33-year-old fish fancier developed a protracted skin infection that ultimately was found to be caused by Mycobacterium marinum. The organism was isolated from the lesion as well as from infected fish taken from his home aquarium. The lesion resolved after a six-week course of oral sulfamethoxazole and trimethoprim. Forty-four additional cases of culture-proved M marinum skin infections acquired from aquariums and reported in the English-language literature are reviewed. Almost universally, the lesions remained circumscribed and were either single nodular (14 patients) or multiple sporotrichoid (31 patients). Diagnosis was supported by acid-fast smears (15 patients) and isolation of the organism from skin lesions (43 patients) or from fish (two cases). In vitro studies, as well as clinical outcomes, suggest sulfamethoxazole-trimethoprim or ethambutol hydrochloride plus rifampin to be the drugs of choice.

Topics: Adult; Animals; Anti-Bacterial Agents; Drug Combinations; Fish Diseases; Fishes; Hand Dermatoses; Hobbies; Humans; Male; Mycobacterium Infections; Mycobacterium Infections, Nontuberculous; Nontuberculous Mycobacteria; Skin Diseases, Infectious; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination