trimethoprim--sulfamethoxazole-drug-combination and Genital-Diseases--Female

Topics: Anti-Bacterial Agents; Chlamydia trachomatis; Doxycycline; Erythromycin; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Lymphogranuloma Venereum; Male; Pregnancy; Pregnancy Complications, Infectious; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

In Yaoundé, chancroid occurs frequently among adolescents and young men (95 p. 100 of the cases) who have sexual contacts regularly with prostitutes. Apart of classical clinical forms complicated in 2/3 of cases by inguinal adenopathies, we have observed furuncular chancroid which is quite characteristic of the disease. Giemsa stain represents for us a simple and reliable diagnostic method for this disease because in 1/3 of smears, typical cultural aspects of Haemophilus ducreyi were seen.

Topics: Adolescent; Adult; Cameroon; Chancroid; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Trimethoprim, Sulfamethoxazole Drug Combination

For prevention of postoperative cystitis the authors tested currently used drugs which influence the adherence of bacteria to the urothelium, nitrofurantoin (FurantoinR), 3 x 1 tabl. per day and trimetroprim with clotrimoxazole (BiseptolR), one tablet in the evening before operation. They found that Furantoin reduced the frequency of the inflammation in patients subjected to abdominal operations from 12.3% in the control group to 2.3% and in those subjected to vaginal operations from 46.1% to 9.6%. The disadvantage of the drug is that it must be taken every day and that it is poorly tolerated by the patients. Biseptol is excreted more slowly and therefore 1 tablet before operation blocks the development for a maximum of 48 hours. In patients with abdominal operations the frequency of inflammation was similarly as in controls, 12%, in patients with vaginal operations the number of inflammations declined to 24.5%. Biseptol, 1 tablet before operation, is suitable only in patients where it is not assumed that the catheter will be inserted for a prolonged period.

Topics: Cystitis; Drug Therapy, Combination; Female; Genital Diseases, Female; Humans; Nitrofurantoin; Postoperative Complications; Premedication; Trimethoprim, Sulfamethoxazole Drug Combination

Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Female; Humans; Male; Penile Diseases; Serologic Tests; Sex Work; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer

Topics: Boston; Chancroid; Disease Outbreaks; Drug Combinations; Erythromycin; Female; Genital Diseases, Female; Humans; Male; Penile Diseases; Serologic Tests; Sex Work; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Ulcer