trimethoprim--sulfamethoxazole-drug-combination has been researched along with Cyanosis* in 2 studies
2 other study(ies) available for trimethoprim--sulfamethoxazole-drug-combination and Cyanosis
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Acute intoxication with propafenone and trimethoprim-sulfamethoxazole in a case of suicide attempt.
A 17-year-old male ingested about 20 tablets of propafenone (total 6,000 mg) and 24 tablets of trimethoprim (total 1,920 mg)--sulfamethoxazole (total 9,600 mg) with suicidal intent. Within one hour, he was brought to a hospital with vomiting, nausea, and loss of consciousness, where he developed cyanosis and mild acidosis, and eventually cardiorespiratory arrest, despite bicarbonate, saline infusion, and inotropic support. Fortunately, he was fully resuscitated and ventilated, and sinus rhythm was restored. He was then transported to our center. On admission, his heart rate was regular with 55 beats/min and blood pressure was 70/45 mmHg. The 12-lead electrocardiogram (ECG) showed sinus bradycardia, extreme widening of the QRS complex (260 msec) with a right bundle branch block pattern. Intravenous saline, bicarbonate, and dopamine were administered, and respiration was supported mechanically, which resulted in rapid restoration of sinus rhythm and improvement in hemodynamic parameters and acidosis. A subsequent ECG showed shortening of the QRS duration (230 msec). He was discharged with an appropriate hemodynamic balance on the third day with normal ECG findings. Topics: Acidosis; Bicarbonates; Cyanosis; Dopamine; Echocardiography, Transesophageal; Electrocardiography; Humans; Male; Middle Aged; Propafenone; Sodium Chloride; Suicide, Attempted; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2009 |
Acrocyanosis of cold agglutinin disease successfully treated with antibiotics.
Two women were seen for evaluation of acrocyanosis and vasculitis limited to the toes. General studies showed only the presence of low titer cold hemagglutinins. Complete rapid clearing of the cutaneous changes was achieved after treatment with systemic cephradine in one case and penicillin in the other. This supports the view that cold agglutinins, arising as a result of occult bacterial infection, were responsible for the clinical presentation of blue toes. Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Bacterial Infections; Cephalosporins; Cephradine; Cyanosis; Drug Combinations; Female; Humans; Penicillin V; Sulfamethoxazole; Toes; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1984 |