trimethoprim--sulfamethoxazole-drug-combination and Anti-Glomerular-Basement-Membrane-Disease

Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative anti-GBM antibodies in plasma is even less frequent We report a 63 years old male in whom anti-GBM disease recurred without detectable anti-GBM antibodies in plasma, despite having positive antibodies at the onset.

Topics: Anti-Bacterial Agents; Anti-Glomerular Basement Membrane Disease; Autoantibodies; Biopsy; Cyclophosphamide; Fluorescent Antibody Technique; Humans; Kidney Diseases; Kidney Glomerulus; Male; Middle Aged; Prednisone; Recurrence; Trimethoprim, Sulfamethoxazole Drug Combination