trimethobenzamide has been researched along with Vomiting in 18 studies
trimethobenzamide: major descriptor (64-84); on-line search BENZAMIDES (64-84); Index Medicus search TRIMETHOBENZAMIDE (64-84); RN given refers to parent cpd
trimethobenzamide : The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 9.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 5.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| " Oral trimethobenzamide was used to prevent apomorphine-induced nausea." | 5.08 | Intranasal apomorphine rescue therapy for parkinsonian "off" periods. ( Ahlskog, JE; Dewey, RB; Maraganore, DM; Matsumoto, JY, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (77.78) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hauser, RA | 1 |
| Isaacson, S | 1 |
| Clinch, T | 1 |
| BURWELL, JA | 1 |
| WOLFSON, B | 1 |
| PERRYMAN, CR | 1 |
| FOLDES, FF | 1 |
| ROBIN, BA | 1 |
| DAVIDSON, OL | 1 |
| SELENY, FL | 1 |
| SPOEREL, WE | 1 |
| WOYTON, J | 1 |
| SWARD, J | 1 |
| MOERTEL, CG | 1 |
| REITEMEIER, RJ | 1 |
| GAGE, RP | 1 |
| PICHA, E | 1 |
| MARCUS, PS | 1 |
| ETTENBERG, M | 1 |
| WEAVER, LC | 1 |
| RAHDERT, E | 1 |
| RICHARDS, AB | 1 |
| ABREU, BE | 1 |
| NATHAN, LA | 1 |
| PRETORIUS, HM | 1 |
| QUINLAN, DK | 1 |
| MULLA, NP | 1 |
| Dewey, RB | 2 |
| Silver, JM | 1 |
| Koumaras, B | 1 |
| Chen, M | 1 |
| Mirski, D | 1 |
| Potkin, SG | 1 |
| Reyes, P | 1 |
| Warden, D | 1 |
| Harvey, PD | 1 |
| Arciniegas, D | 1 |
| Katz, DI | 1 |
| Gunay, I | 1 |
| Ginsburg, CM | 1 |
| Clahsen, J | 1 |
| Davis, LE | 1 |
| Maraganore, DM | 1 |
| Ahlskog, JE | 1 |
| Matsumoto, JY | 1 |
4 trials available for trimethobenzamide and Vomiting
| Article | Year |
|---|---|
Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antiemetics; Apomorphine; Benzamides; Dopamine | 2014 |
Effects of rivastigmine on cognitive function in patients with traumatic brain injury.
Topics: Adolescent; Adult; Antiemetics; Benzamides; Brain Injuries; Cognition Disorders; Dose-Response Relat | 2006 |
Evaluation of trimethobenzamide hydrochloride (Tigan) suppositories for treatment of nausea and vomiting in children.
Topics: Adolescent; Benzamides; Child; Child, Preschool; Evaluation Studies as Topic; Female; Humans; Infant | 1980 |
Intranasal apomorphine rescue therapy for parkinsonian "off" periods.
Topics: Administration, Intranasal; Antiemetics; Antiparkinson Agents; Apomorphine; Benzamides; Carbidopa; D | 1996 |
14 other studies available for trimethobenzamide and Vomiting
| Article | Year |
|---|---|
The use of trimethobenzamide (tigan) for the treatment of radiation induced nausea and emesis.
Topics: Benzamides; Benzoates; Humans; Nausea; Radiotherapy; Vomiting | 1961 |
Comparative study of the effectiveness of tigan and a placebo in controlling emesis.
Topics: Antiemetics; Benzamides; Gastrointestinal Contents; Humans; Vomiting | 1960 |
Clinical experience with a combination of trimethobenzamide and pyridoxine in patients with nausea and vomiting of pregnancy.
Topics: Antiemetics; Benzamides; Female; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; Pregnancy Compli | 1960 |
Observations on postoperative vomiting.
Topics: Antiemetics; Benzamides; Cyclizine; Humans; Postoperative Nausea and Vomiting; Surgical Procedures, | 1963 |
[Results of the treatment of persistent vomiting with Tigan and Theadryl].
Topics: Anti-Allergic Agents; Antiemetics; Benzamides; Benzoates; Histamine H1 Antagonists; Vomiting | 1962 |
A CONTROLLED CLINICAL EVALUATION OF ANTIEMETIC DRUGS.
Topics: Antiemetics; Benzamides; Fluorouracil; Humans; Pharmacology; Prochlorperazine; Tranquilizing Agents; | 1963 |
USE OF A NEW ANTIEMETIC IN GYNECOLOGICAL RADIATION THERAPY.
Topics: Antiemetics; Benzamides; Gynecology; Humans; Intestinal Obstruction; Peritonitis; Radioisotopes; Rad | 1964 |
ANTIEMETIC PROPHYLAXIS IN ADENOTONSILLECTOMIES; A DOUBLE-BLIND STUDY.
Topics: Adenoidectomy; Antiemetics; Benzamides; Biomedical Research; Child; Double-Blind Method; Drug Therap | 1964 |
EFFECT OF ANTIEMETICS AND OTHER COMPOUNDS ON PROTOVERATRINE INDUCED EMESIS IN DOGS.
Topics: Antiemetics; Atropine; Benzamides; Dogs; Haloperidol; Meclizine; Niacin; Perphenazine; Pharmacology; | 1964 |
Pediatric use of trimethobenzamide, a specific antiemetic.
Topics: Antiemetics; Benzamides; Child; Humans; Infant; Pediatrics; Vomiting | 1960 |
Nausea and vomiting in pregnancy. A report of a new drug trimethobenzamide (Tigan).
Topics: Antiemetics; Benzamides; Benzoates; Nausea; Pregnancy; Vomiting | 1961 |
EVALUATION OF TRIMETHOBENZAMIDE WITH PYRIDOXINE IN NAUSEA AND VOMITING OF PREGNANCY.
Topics: Benzamides; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting | 1963 |
10 questions about using apomorphine for Parkinson disease.
Topics: Antiemetics; Antiparkinson Agents; Apomorphine; Benzamides; Humans; Injections, Intravenous; Parkins | 2005 |
Pharmacologic control of vomiting.
Topics: Animals; Antiemetics; Benzamides; Cats; Dogs; Haloperidol; Motion Sickness; Phenothiazines; Swine; V | 1980 |