trimethobenzamide has been researched along with Nausea in 9 studies
trimethobenzamide: major descriptor (64-84); on-line search BENZAMIDES (64-84); Index Medicus search TRIMETHOBENZAMIDE (64-84); RN given refers to parent cpd
trimethobenzamide : The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 9.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 5.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| " Oral trimethobenzamide was used to prevent apomorphine-induced nausea." | 5.08 | Intranasal apomorphine rescue therapy for parkinsonian "off" periods. ( Ahlskog, JE; Dewey, RB; Maraganore, DM; Matsumoto, JY, 1996) |
| " In the present study, the role of nausea in TCDD-induced hypophagia was assessed by a battery of behavioral (conditioned taste aversion [CTA], kaolin consumption, protein selection), biochemical (plasma oxytocin), and antiemetic drug intervention (trimethobenzamine, metoclopramide) approaches." | 3.69 | TCDD-induced hypophagia is not explained by nausea. ( Pohjanvirta, R; Tuomisto, J; Unkila, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hauser, RA | 1 |
| Isaacson, S | 1 |
| Clinch, T | 1 |
| BURWELL, JA | 1 |
| WOLFSON, B | 1 |
| PERRYMAN, CR | 1 |
| FOLDES, FF | 1 |
| MOLANDER, DW | 1 |
| DAVIDSON, OL | 1 |
| PRETORIUS, HM | 1 |
| QUINLAN, DK | 1 |
| MULLA, NP | 1 |
| Ginsburg, CM | 1 |
| Clahsen, J | 1 |
| Pohjanvirta, R | 1 |
| Unkila, M | 1 |
| Tuomisto, J | 1 |
| Dewey, RB | 1 |
| Maraganore, DM | 1 |
| Ahlskog, JE | 1 |
| Matsumoto, JY | 1 |
3 trials available for trimethobenzamide and Nausea
| Article | Year |
|---|---|
Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antiemetics; Apomorphine; Benzamides; Dopamine | 2014 |
Evaluation of trimethobenzamide hydrochloride (Tigan) suppositories for treatment of nausea and vomiting in children.
Topics: Adolescent; Benzamides; Child; Child, Preschool; Evaluation Studies as Topic; Female; Humans; Infant | 1980 |
Intranasal apomorphine rescue therapy for parkinsonian "off" periods.
Topics: Administration, Intranasal; Antiemetics; Antiparkinson Agents; Apomorphine; Benzamides; Carbidopa; D | 1996 |
6 other studies available for trimethobenzamide and Nausea
| Article | Year |
|---|---|
The use of trimethobenzamide (tigan) for the treatment of radiation induced nausea and emesis.
Topics: Benzamides; Benzoates; Humans; Nausea; Radiotherapy; Vomiting | 1961 |
Use of trimethobenzamide in nausea associated with neoplastic disease.
Topics: Benzamides; Benzoates; Humans; Nausea; Neoplasms | 1961 |
Clinical experience with a combination of trimethobenzamide and pyridoxine in patients with nausea and vomiting of pregnancy.
Topics: Antiemetics; Benzamides; Female; Humans; Hyperemesis Gravidarum; Nausea; Pregnancy; Pregnancy Compli | 1960 |
Nausea and vomiting in pregnancy. A report of a new drug trimethobenzamide (Tigan).
Topics: Antiemetics; Benzamides; Benzoates; Nausea; Pregnancy; Vomiting | 1961 |
EVALUATION OF TRIMETHOBENZAMIDE WITH PYRIDOXINE IN NAUSEA AND VOMITING OF PREGNANCY.
Topics: Benzamides; Female; Humans; Nausea; Pregnancy; Pregnancy Complications; Pyridoxine; Vomiting | 1963 |
TCDD-induced hypophagia is not explained by nausea.
Topics: Animals; Antiemetics; Benzamides; Body Weight; Eating; Energy Metabolism; Female; Kaolin; Male; Meto | 1994 |