trimethobenzamide has been researched along with Idiopathic Parkinson Disease in 4 studies
trimethobenzamide: major descriptor (64-84); on-line search BENZAMIDES (64-84); Index Medicus search TRIMETHOBENZAMIDE (64-84); RN given refers to parent cpd
trimethobenzamide : The amide obtained by formal condensation of 3,4,5-trihydroxybenzoic acid with 4-[2-(N,N-dimethylamino)ethoxy]benzylamine. It is used to prevent nausea and vomitting in humans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 9.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| "Incidence of nausea and/or vomiting on Day 1 of apomorphine initiation (primary endpoint) was not significantly different between trimethobenzamide and placebo." | 5.19 | Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection. ( Clinch, T; Hauser, RA; Isaacson, S, 2014) |
| " Oral trimethobenzamide was used to prevent apomorphine-induced nausea." | 5.08 | Intranasal apomorphine rescue therapy for parkinsonian "off" periods. ( Ahlskog, JE; Dewey, RB; Maraganore, DM; Matsumoto, JY, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hauser, RA | 1 |
| Isaacson, S | 1 |
| Clinch, T | 1 |
| Dewey, RB | 3 |
| Maraganore, DM | 2 |
| Ahlskog, JE | 2 |
| Matsumoto, JY | 2 |
3 trials available for trimethobenzamide and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antiemetics; Apomorphine; Benzamides; Dopamine | 2014 |
Intranasal apomorphine rescue therapy for parkinsonian "off" periods.
Topics: Administration, Intranasal; Antiemetics; Antiparkinson Agents; Apomorphine; Benzamides; Carbidopa; D | 1996 |
A double-blind, placebo-controlled study of intranasal apomorphine spray as a rescue agent for off-states in Parkinson's disease.
Topics: Administration, Intranasal; Aerosols; Aged; Antiemetics; Antiparkinson Agents; Apomorphine; Benzamid | 1998 |
1 other study available for trimethobenzamide and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
10 questions about using apomorphine for Parkinson disease.
Topics: Antiemetics; Antiparkinson Agents; Apomorphine; Benzamides; Humans; Injections, Intravenous; Parkins | 2005 |