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trimethadione and Myasthenia Gravis

trimethadione has been researched along with Myasthenia Gravis in 4 studies

Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.

Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peterson, H1
Booker, HE2
Chun, RW2
Sanguino, M2
Gilbert, GJ1

Other Studies

4 other studies available for trimethadione and Myasthenia Gravis

ArticleYear
Association of trimethadione therapy and myasthenia gravis.
    The New England journal of medicine, 1966, Mar-03, Volume: 274, Issue:9

    Topics: Anticonvulsants; Autoimmune Diseases; Child; Epilepsy, Absence; Female; Humans; Myasthenia Gravis; T

1966
Myasthenic syndrome associated with trimethadione.
    Neurology, 1968, Volume: 18, Issue:3

    Topics: Anticonvulsants; Autoantibodies; Child; Epilepsy, Absence; Female; Humans; Myasthenia Gravis; Oxazol

1968
Myasthenia gravis syndrome associated with trimethadione.
    JAMA, 1970, Jun-29, Volume: 212, Issue:13

    Topics: Anticonvulsants; Autoimmune Diseases; Child; Drug Hypersensitivity; Epilepsy, Absence; Female; Human

1970
Myasthenia gravis and epilepsy.
    The Journal of the Florida Medical Association, 1970, Volume: 57, Issue:5

    Topics: Adult; Anticonvulsants; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Myasthenia Gravis

1970