trimethadione has been researched along with Liver Diseases in 9 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethadione (TMO) has the properties required of probe drugs for the evaluation of hepatic drug-oxidizing capacity in humans in vivo." | 2.39 | Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans. ( Abei, M; Ishikawa, A; Kobayashi, S; Tanaka, E, 1996) |
| "Fatty liver is paralleled by the block in Triton-induced hypertriglyceridaemia." | 1.27 | A model for monitoring changes in liver function. ( Aragno, M; Brando, C; Burdino, E; Danni, O; Ugazio, G, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DUBOIS, EL | 1 |
| Snyman, T | 1 |
| Stewart, MJ | 1 |
| Grove, A | 1 |
| Steenkamp, V | 1 |
| Bruni, J | 1 |
| Albright, PS | 1 |
| Tanaka, E | 5 |
| Funae, Y | 1 |
| Ishikawa, A | 2 |
| Abei, M | 1 |
| Kobayashi, S | 1 |
| Yasuhara, H | 1 |
| Breimer, DD | 1 |
| Ono, A | 1 |
| Okamura, T | 1 |
| Misawa, S | 1 |
| Danni, O | 1 |
| Brando, C | 1 |
| Burdino, E | 1 |
| Aragno, M | 1 |
| Ugazio, G | 1 |
4 reviews available for trimethadione and Liver Diseases
| Article | Year |
|---|---|
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal | 1984 |
Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans.
Topics: Administration, Oral; Animals; Clinical Trials as Topic; Dimethadione; Humans; Liver Diseases; Micro | 1996 |
[Evaluation of liver function in liver diseases using drugs as indicators].
Topics: Aminopyrine; Antipyrine; Erythromycin; Humans; Lidocaine; Liver; Liver Diseases; Liver Function Test | 1997 |
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome | 1997 |
5 other studies available for trimethadione and Liver Diseases
| Article | Year |
|---|---|
Toxic hepatic necrosis associated with taking dilantin, tridione and phenobarbital; report of a case.
Topics: Aged; Barbital; Hepatitis; Humans; Hydantoins; Liver; Liver Diseases; Phenobarbital; Phenytoin; Trim | 1950 |
Adulteration of South African traditional herbal remedies.
Topics: Acidosis, Lactic; Adult; Chemical and Drug Induced Liver Injury; Child, Preschool; Chromatography, H | 2005 |
Trimethadione: metabolism and assessment of hepatic drug-oxidizing capacity.
Topics: Animals; Anticonvulsants; Chromatography, Gas; Dimethadione; Humans; In Vitro Techniques; Liver; Liv | 1996 |
Trimethadione metabolism in patients with normal liver and in patients with chronic liver disease.
Topics: Carcinoma, Hepatocellular; Chronic Disease; Dimethadione; Female; Humans; Liver Cirrhosis; Liver Dis | 1987 |
A model for monitoring changes in liver function.
Topics: Animals; Biopsy; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Fatty Liver | 1986 |