trimethadione has been researched along with Libman-Sacks Disease in 5 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drug-induced systemic lupus erythematosus (SLE)-like syndromes in children are most commonly associated with the administration of ethosuximide, diphenylhydantoin, and trimethadione." | 1.26 | Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants. ( Fishman, L; Hanson, V; Singsen, BH, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOLLEY, HL | 1 |
| Singsen, BH | 1 |
| Fishman, L | 1 |
| Hanson, V | 1 |
| Thoenes, W | 1 |
| Thoenes, G | 1 |
| Ansorge, R | 1 |
| Eldredge, NT | 1 |
| van Robertson, WB | 1 |
| Jiller, JJ | 1 |
| Beernink, DH | 1 |
| Miller, JJ | 1 |
5 other studies available for trimethadione and Libman-Sacks Disease
| Article | Year |
|---|---|
EVIDENCE FOR A PREDISPOSITION TO RHEUMATIC DISEASES IN FAMILIES OF PATIENTS DEVELOPING DRUG-INDUCED SYSTEMIC LUPUS ERYTHEMATOSUS.
Topics: Adolescent; Anticonvulsants; Child; Disease Susceptibility; Drug Therapy; Genetics, Medical; Humans; | 1964 |
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide; | 1976 |
[Drug-induced lupus-nephritis light-, electron- and immunfluorescence-microscopic investigations on kidney biopsies (author's transl)].
Topics: Adolescent; Anticonvulsants; Biopsy; Child; Drug-Related Side Effects and Adverse Reactions; Female; | 1972 |
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immu | 1974 |
Anticonvulsant-induced antinuclear antibodies and lupus-like disease in children.
Topics: Adolescent; Adult; Age Factors; Antibodies, Antinuclear; Antibody Formation; Anticonvulsants; Child; | 1973 |