trimethadione has been researched along with Kidney Failure, Chronic in 1 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethadione (TMO) was chosen as an indicator of quantitative hepatic microsomal function, and its pharmacokinetics were studied in 52 patients with chronic hepatitis." | 7.69 | Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity. ( Abei, M; Ikegami, T; Ishikawa, A; Matsuzaki, Y; Osuga, T; Tanaka, E; Tanaka, N, 1995) |
| "Trimethadione (TMO) was chosen as an indicator of quantitative hepatic microsomal function, and its pharmacokinetics were studied in 52 patients with chronic hepatitis." | 3.69 | Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity. ( Abei, M; Ikegami, T; Ishikawa, A; Matsuzaki, Y; Osuga, T; Tanaka, E; Tanaka, N, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abei, M | 1 |
| Tanaka, E | 1 |
| Tanaka, N | 1 |
| Matsuzaki, Y | 1 |
| Ikegami, T | 1 |
| Ishikawa, A | 1 |
| Osuga, T | 1 |
1 other study available for trimethadione and Kidney Failure, Chronic
| Article | Year |
|---|---|
Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity.
Topics: Chronic Disease; Dimethadione; Drug Tolerance; Female; Hepatitis; Hepatitis B; Hepatitis C; Hepatiti | 1995 |