trimethadione has been researched along with Intraventricular Septal Defects in 2 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Congenital membranous ventricular septal defects (VSD) have been shown to close during postnatal development in rats [Solomon et al." | 1.32 | Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione. ( Cappon, GD; Fleeman, TL; Hurtt, ME, 2004) |
| "Membranous ventricular septal defects (VSDs) were observed in 2." | 1.30 | Spontaneous and induced alterations in the cardiac membranous ventricular septum of fetal, weanling, and adult rats. ( Fish, CJ; Gowan, CC; Hart, TK; Johnson, CM; Kerns, WD; Maleeff, BE; Posobiec, LM; Solomon, HM; Wier, PJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fleeman, TL | 1 |
| Cappon, GD | 1 |
| Hurtt, ME | 1 |
| Solomon, HM | 1 |
| Wier, PJ | 1 |
| Fish, CJ | 1 |
| Hart, TK | 1 |
| Johnson, CM | 1 |
| Posobiec, LM | 1 |
| Gowan, CC | 1 |
| Maleeff, BE | 1 |
| Kerns, WD | 1 |
2 other studies available for trimethadione and Intraventricular Septal Defects
| Article | Year |
|---|---|
Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione.
Topics: Animals; Anticonvulsants; Body Weight; Dose-Response Relationship, Drug; Female; Heart Septal Defect | 2004 |
Spontaneous and induced alterations in the cardiac membranous ventricular septum of fetal, weanling, and adult rats.
Topics: Animals; Diet, Reducing; Female; Fetal Growth Retardation; Fetus; Heart Septal Defects, Ventricular; | 1997 |