Page last updated: 2024-11-05

trimethadione and Heart Defects, Congenital

trimethadione has been researched along with Heart Defects, Congenital in 6 studies

Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.

Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Harned, HS	1
Rischbieth, RH	1
Anderson, RC	1
German, J	1
Ehlers, KH	1
Kowal, A	1
De George, FV	1
Engle, MA	1
Passarge, E	1
Nichols, MM	1

Reviews

1 review available for trimethadione and Heart Defects, Congenital

Article	Year
Cardiovascular problems of the newborn and their etiologies. Progress in clinical and biological research, 1983, Volume: 140 Topics: Amphetamines; Animals; Cardiovascular Diseases; Estrogens; Ethanol; Female; Fetal Hypoxia; Heart Def	1983

Other Studies

5 other studies available for trimethadione and Heart Defects, Congenital

Article	Year
American Academy of Pediatrics Committee on Drugs: anticonvulsants and pregnancy. Pediatrics, 1979, Volume: 63, Issue:2 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec	1979
Troxidone (trimethadione) embryopathy: case report with reveiw of the literature. Clinical and experimental neurology, 1979, Volume: 16 Topics: Abnormalities, Drug-Induced; Aorta; Child; Ductus Arteriosus, Patent; Ear, External; Female; Heart D	1979
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy. The Journal of pediatrics, 1976, Volume: 89, Issue:2 Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadio	1976
Possible teratogenicity of trimethadione and paramethadione. Lancet (London, England), 1970, Aug-01, Volume: 2, Issue:7666 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Epilepsy; Female; Heart Defec	1970
Fetal anomalies following maternal trimethadione ingestion. The Journal of pediatrics, 1973, Volume: 82, Issue:5 Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Female; Heart Defects, Congen	1973