trimethadione has been researched along with Epilepsy, Tonic-Clonic in 15 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BELNAP, WD | 1 |
| TOMAN, JE | 1 |
| GOODMAN, LS | 1 |
| Rosen, RC | 1 |
| Lightner, ES | 1 |
| Goodman, RM | 1 |
| Katznelson, MB | 1 |
| Hertz, M | 1 |
| Katznelson, D | 1 |
| Rotem, Y | 1 |
| Thomas, JA | 1 |
| Knotts, GR | 1 |
| Krip, G | 1 |
| Vazquez, AJ | 1 |
| Lippe, BM | 1 |
| Crandall, BF | 1 |
| Saper, JR | 1 |
| Lossing, JH | 1 |
| Millichap, JG | 1 |
| Hooshmand, H | 1 |
| Suter, CG | 1 |
| Jannasch, R | 1 |
| Livingston, S | 1 |
| Torres, I | 1 |
| Pauli, LL | 1 |
| Rider, RV | 1 |
| Charlton, MH | 1 |
| Yahr, MD | 1 |
| Northway, JD | 1 |
| West, CD | 1 |
| Shimazono, Y | 1 |
| Fukuta, T | 1 |
| Gilbert, GJ | 1 |
2 reviews available for trimethadione and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
[Antiepileptics. 39].
Topics: Acetazolamide; Adrenocorticotropic Hormone; Aminoglutethimide; Anticonvulsants; Barbiturates; Carbam | 1969 |
[Drug therapy of epilepsy].
Topics: Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Trimethadione; Urea | 1967 |
13 other studies available for trimethadione and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Tridione-diphenylhydantoin combination therapy in grand mal with slow-wave EEG dysrhythmia.
Topics: Combined Modality Therapy; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenyto | 1947 |
Phenotypic malformations in association with maternal trimethadione therapy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Epilepsy, Absence; Epilepsy, Tonic-Clon | 1978 |
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epil | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1976 |
Effects of diphenylhydantoin and cholinergic agents on the neuronally isolated cerebral cortex.
Topics: Animals; Atropine; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; | 1971 |
Turner syndrome with partial deletion of the X chromosome long arm.
Topics: Adolescent; Amenorrhea; Dermatoglyphics; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Follicle | 1973 |
Prolonged trance-like stupor in epilepsy. Petit mal status-wave stupor, spaced-out status.
Topics: Adult; Behavior; Diagnosis, Differential; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Abse | 1974 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; E | 1972 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, | 1970 |
Petit mal epilepsy. Results of a prolonged follow-up study of 117 patients.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Tonic-Clon | 1965 |
Long-term follow-up of patients with petit mal.
Topics: Adolescent; Adult; Aging; Child; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; | 1967 |
Successful therapy of trimethadione nephrosis with prednisone and cyclophosphamide. Report of a case.
Topics: Anticonvulsants; Birth Injuries; Child, Preschool; Cyclophosphamide; Epilepsy, Tonic-Clonic; Female; | 1967 |
Myasthenia gravis and epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Female; Humans; Myasthenia Gravis | 1970 |