trimethadione has been researched along with Complications, Pregnancy in 19 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 7.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 3.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| "Only trimethadione has been convincingly linked to fetal malformation." | 2.36 | The pregnant epileptic: a review and recommendations. ( Fenichel, GM; McLain, LW; Montouris, GD, 1979) |
| "The dislocation of the hip and the patent ductus arteriosus have been corrected surgically." | 1.25 | Persistent fifth aortic arch in man. ( Lawrence, TY; Stiles, QR, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weitz, R | 1 |
| Merlob, P | 1 |
| Kelly, TE | 1 |
| Friis, ML | 1 |
| Clifford, DB | 1 |
| Goldner, JC | 1 |
| Zackai, EH | 1 |
| Mellman, WJ | 1 |
| Neiderer, B | 1 |
| Hanson, JW | 1 |
| Montouris, GD | 1 |
| Fenichel, GM | 1 |
| McLain, LW | 1 |
| Feldman, GL | 1 |
| Weaver, DD | 1 |
| Lovrien, EW | 1 |
| Goldman, AS | 1 |
| Yaffe, SJ | 1 |
| Smith, DW | 1 |
| Anderson, RC | 1 |
| Biale, Y | 1 |
| Lewenthal, H | 1 |
| Aderet, NB | 1 |
| Lawrence, TY | 1 |
| Stiles, QR | 1 |
| Piccione, E | 1 |
| Ticconi, C | 1 |
| Cennamo, M | 1 |
| Dalessio, DJ | 1 |
| Stumpf, DA | 1 |
| German, J | 1 |
| Ehlers, KH | 1 |
| Kowal, A | 1 |
| De George, FV | 1 |
| Engle, MA | 1 |
| Passarge, E | 1 |
| Zellweger, H | 1 |
5 reviews available for trimethadione and Complications, Pregnancy
| Article | Year |
|---|---|
Teratogenicity of anticonvulsant drugs. I: Review of the literature.
Topics: Animals; Anticonvulsants; Epilepsy; Female; Humans; Hydantoins; Pregnancy; Pregnancy Complications; | 1984 |
The pregnant epileptic: a review and recommendations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetus; Humans; Infant, Newborn; Kine | 1979 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; | 1989 |
Current concepts. Seizure disorders and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Epilepsy; | 1985 |
Anticonvulsants during pregnancy: a danger to the developing fetus?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Barbiturates; Blood Coagulation Disorders; Chromosome | 1974 |
14 other studies available for trimethadione and Complications, Pregnancy
| Article | Year |
|---|---|
[Fetal trimethadione syndrome and behavior disorders in children of epilectic mothers].
Topics: Child; Epilepsy; Female; Fetal Diseases; Humans; Male; Mental Disorders; Pregnancy; Pregnancy Compli | 1979 |
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newbo | 1983 |
Seizures and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetal Diseases; Humans; Hydantoins; | 1984 |
Anticonvulsants and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Humans; Infant, Newborn; Maternal-Fe | 1981 |
The fetal trimethadione syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental | 1975 |
The fetal trimethadione syndrome: report of an additional family and further delineation of this syndrome.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Drug Therapy, Combination; Epilepsy, Absence; Fe | 1977 |
American Academy of Pediatrics Committee on Drugs: anticonvulsants and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cleft Lip; Cleft Palate; Epilepsy; Female; Heart Defec | 1979 |
Fetal trimethadione syndrome.
Topics: Abnormalities, Drug-Induced; Ear, External; Epilepsy; Eyebrows; Female; Humans; Male; Oxazoles; Pala | 1978 |
Teratogenicity of anticonvulsive medications.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Barbiturates; Drug Therapy, Combination; Epilepsy; Fem | 1977 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadio | 1976 |
Congenital malformations due to anticonvulsive drugs.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord | 1975 |
Persistent fifth aortic arch in man.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Aorta; Child, Preschool; Ductus Arteriosus, Pa | 1975 |
Anticonvulsant use during pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Fetal Death; Humans; Phenobarbital; | 1985 |
Possible teratogenicity of trimethadione and paramethadione.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Epilepsy; Female; Heart Defec | 1970 |