trimethadione has been researched along with Carbon Tetrachloride Poisoning in 5 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fatty liver is paralleled by the block in Triton-induced hypertriglyceridaemia." | 1.27 | A model for monitoring changes in liver function. ( Aragno, M; Brando, C; Burdino, E; Danni, O; Ugazio, G, 1986) |
| "6 h and 163 microgram/ml at 8 h and declined with a half-life of 2." | 1.26 | Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced liver injury. ( Kinoshita, H; Kuroiwa, Y; Takabatake, E; Tanaka, E; Yamamoto, T, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, E | 4 |
| Kinoshita, H | 2 |
| Yamamoto, T | 1 |
| Kuroiwa, Y | 2 |
| Takabatake, E | 1 |
| Yoshida, T | 1 |
| Ishikawa, A | 2 |
| Misawa, S | 2 |
| Tsuji, K | 1 |
| Fukao, K | 1 |
| Iwasaki, Y | 1 |
| Danni, O | 1 |
| Brando, C | 1 |
| Burdino, E | 1 |
| Aragno, M | 1 |
| Ugazio, G | 1 |
5 other studies available for trimethadione and Carbon Tetrachloride Poisoning
| Article | Year |
|---|---|
Pharmacokinetic studies of trimethadione and its metabolite in rats with chemical-induced liver injury.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Biotransformation; Carbon Tetrachloride Poi | 1981 |
Determination of plasma trimethadione and its metabolite carbon tetrachloride-intoxicated rat liver: a useful tool for estimation of hepatic drug metabolizing capacity.
Topics: Animals; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Dimethadione; In Vitro Tech | 1981 |
Simplified test for determination of drug-oxidizing capacity in rats with chemical-induced liver injury using caffeine and trimethadione as model drugs.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Caffeine; Carbon Tetrachloride Poisoning; G | 1992 |
[Measurement of microsomal function in hepatectomized rat].
Topics: Animals; Carbon Tetrachloride Poisoning; Dimethadione; Hepatectomy; Liver; Male; Microsomes, Liver; | 1987 |
A model for monitoring changes in liver function.
Topics: Animals; Biopsy; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Fatty Liver | 1986 |