Compounds > trimethadione
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trimethadione and Brain Injuries

trimethadione has been researched along with Brain Injuries in 3 studies

Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.

Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pastore, V1
Wasowski, C1
Higgs, J1
Mangialavori, IC1
Bruno-Blanch, LE1
Marder, M1
Friedlander, WJ1
Swinyard, EA1

Reviews

2 reviews available for trimethadione and Brain Injuries

ArticleYear
Epilepsy.
    Progress in neurology and psychiatry, 1967, Volume: 22

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Amphetamine; Anesthetics, Local; Anticonvulsants; Ba

1967
Laboratory evaluation of antiepileptic drugs. Review of laboratory methods.
    Epilepsia, 1969, Volume: 10, Issue:2

    Topics: Animals; Anticonvulsants; Biological Assay; Brain Injuries; Diagnosis; Electroconvulsive Therapy; El

1969

Other Studies

1 other study available for trimethadione and Brain Injuries

ArticleYear
A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:8

    Topics: Animals; Anticonvulsants; Antidepressive Agents; Brain Injuries; Disease Models, Animal; Flunitrazep

2014