trimethadione has been researched along with Body Weight in 4 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Congenital membranous ventricular septal defects (VSD) have been shown to close during postnatal development in rats [Solomon et al." | 1.32 | Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione. ( Cappon, GD; Fleeman, TL; Hurtt, ME, 2004) |
| " At dosage levels equimolar to 500 ppm PB, none of the three compounds promoted development of hepatocellular adenomas or carcinomas, in contrast to PB." | 1.28 | Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat. ( Diwan, BA; Henneman, JR; Lubet, RA; Nims, RW; Rice, JM; Ward, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fleeman, TL | 1 |
| Cappon, GD | 1 |
| Hurtt, ME | 1 |
| Diwan, BA | 1 |
| Nims, RW | 1 |
| Henneman, JR | 1 |
| Ward, JM | 1 |
| Lubet, RA | 1 |
| Rice, JM | 1 |
| Hooshmand, H | 1 |
| Endröczi, E | 1 |
| Fekete, T | 1 |
1 review available for trimethadione and Body Weight
| Article | Year |
|---|---|
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weig | 1974 |
3 other studies available for trimethadione and Body Weight
| Article | Year |
|---|---|
Postnatal closure of membranous ventricular septal defects in Sprague-Dawley rat pups after maternal exposure with trimethadione.
Topics: Animals; Anticonvulsants; Body Weight; Dose-Response Relationship, Drug; Female; Heart Septal Defect | 2004 |
Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.
Topics: Animals; Barbiturates; Body Weight; Cocarcinogenesis; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzy | 1992 |
Amino acid composition of the Ammon's horn and the effect of anticonvulsant drugs.
Topics: Amino Acids; Animals; Anticonvulsants; Body Weight; Brain Chemistry; Chromatography, Paper; DNA; Hip | 1967 |