trimethadione has been researched along with Arrhythmia in 3 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is evidence that drug-induced embryonic arrhythmia initiates phenytoin (PHT) teratogenicity." | 3.71 | Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? ( Azarbayjani, F; Danielsson, BR, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azarbayjani, F | 2 |
| Danielsson, BR | 2 |
| Singh, N | 1 |
| Sinha, JN | 1 |
| Rastogi, SK | 1 |
| Dua, PR | 1 |
| Kohli, RP | 1 |
3 other studies available for trimethadione and Arrhythmia
| Article | Year |
|---|---|
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; | 1998 |
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Anticonvulsants; Arrhythmias, Cardiac; Cation Tra | 2002 |
An experimental investigation on the antiarrhythmic activity of antiepileptic agents.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Coronary Vessels; | 1971 |