trimethadione has been researched along with Adverse Drug Event in 6 studies
Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| HOLOWACH, J | 1 |
| SANDEN, HV | 1 |
| Jakubski, B | 1 |
| Thoenes, W | 1 |
| Thoenes, G | 1 |
| Ansorge, R | 1 |
| Nishimura, H | 1 |
| Tanimura, T | 1 |
2 reviews available for trimethadione and Adverse Drug Event
| Article | Year |
|---|---|
[Drugs and the kidney].
Topics: Analgesics; Anti-Bacterial Agents; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reac | 1979 |
[Drugs and congenital anomalies of the central nervous system].
Topics: Abnormalities, Drug-Induced; Animals; Brain; Carbon Monoxide Poisoning; Central Nervous System; Drug | 1972 |
4 other studies available for trimethadione and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Alopecia as a side effect of treatment of epilepsy with trimethadione. Report of two cases.
Topics: Alopecia; Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Humans; Iatrog | 1960 |
[Drug-induced lupus-nephritis light-, electron- and immunfluorescence-microscopic investigations on kidney biopsies (author's transl)].
Topics: Adolescent; Anticonvulsants; Biopsy; Child; Drug-Related Side Effects and Adverse Reactions; Female; | 1972 |