Page last updated: 2024-11-05

trimethadione and Abnormalities, Multiple

trimethadione has been researched along with Abnormalities, Multiple in 9 studies

Trimethadione: An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)
trimethadione : An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent.

Abnormalities, Multiple: Congenital abnormalities that affect more than one organ or body structure.

Research Excerpts

ExcerptRelevanceReference
"Three families are described in which each of the mothers took trimethadione during pregnancy."7.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
"Three families are described in which each of the mothers took trimethadione during pregnancy."3.65The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975)
"The dislocation of the hip and the patent ductus arteriosus have been corrected surgically."1.25Persistent fifth aortic arch in man. ( Lawrence, TY; Stiles, QR, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qin, W1
Hu, ZY1
Tong, JW1
Meng, J1
You, XF1
Zhang, JP1
Nakane, Y1
Zackai, EH1
Mellman, WJ1
Neiderer, B1
Hanson, JW1
Rosen, RC1
Lightner, ES1
Goodman, RM1
Katznelson, MB1
Hertz, M1
Katznelson, D1
Rotem, Y1
Biale, Y1
Lewenthal, H1
Aderet, NB1
Lawrence, TY1
Stiles, QR1
German, J2
Ehlers, KH2
Kowal, A2
De George, FV1
Engle, MA1
Passarge, E1

Reviews

1 review available for trimethadione and Abnormalities, Multiple

ArticleYear
[Fetal trimethadione effects].
    Ryoikibetsu shokogun shirizu, 2000, Issue:30 Pt 5

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Diagnosis, Differential; Fema

2000

Other Studies

8 other studies available for trimethadione and Abnormalities, Multiple

ArticleYear
[Toxic effects of trimethadione on zebrafish early development].
    Yi chuan = Hereditas, 2012, Volume: 34, Issue:9

    Topics: Abnormalities, Multiple; Animals; Embryonic Development; Gene Expression Profiling; Gene Expression

2012
The fetal trimethadione syndrome.
    The Journal of pediatrics, 1975, Volume: 87, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental

1975
Phenotypic malformations in association with maternal trimethadione therapy.
    The Journal of pediatrics, 1978, Volume: 92, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Epilepsy, Absence; Epilepsy, Tonic-Clon

1978
Congenital malformations in four siblings of a mother taking anticonvulsant drugs.
    American journal of diseases of children (1960), 1976, Volume: 130, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Child; Child, Preschool; Epil

1976
Congenital malformations due to anticonvulsive drugs.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:4

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord

1975
Persistent fifth aortic arch in man.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:10

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Aorta; Child, Preschool; Ductus Arteriosus, Pa

1975
Possible teratogenicity of trimethadione and paramethadione.
    Lancet (London, England), 1970, Aug-01, Volume: 2, Issue:7666

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anticonvulsants; Epilepsy; Female; Heart Defec

1970
Trimethadione and human teratogenesis.
    Teratology, 1970, Volume: 3, Issue:4

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Abortion, Spontaneous; Adult; Epilepsy, Absenc

1970