trimetazidine has been researched along with Reperfusion Injury in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (21.88) | 18.2507 |
| 2000's | 30 (46.88) | 29.6817 |
| 2010's | 14 (21.88) | 24.3611 |
| 2020's | 6 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Ahangarpour, A; Amini, N; Badavi, M; Dianat, M; Mard, SA; Sarkaki, A | 3 |
| Martin, LC | 1 |
| Arpa, M; Deniz, E; Duman Ozturk, S; Kutlu Yilmaz, E; Ozturk, A; Topcu, A | 1 |
| Ferencz, S; Fincsur, A; Nemeth, B; Palkovics, A; Papp, A; Takacs, I; Vereczkei, A | 1 |
| Abdallah, HA; Aboulhoda, BE; Al Dreny, BA; Alghamdi, MA; Ali, IH; Elwi, HM; Hassan, FE; Khalifa, MM; Matter, LM; Morsy, SA; Selmy, A | 1 |
| Liu, C; Zheng, W | 1 |
| Liu, H; Lu, S; Yu, L | 1 |
| Arni, S; Cosgun, T; Inci, I; Iskender, I; Lipiski, M; van Tilburg, K; Weder, W; Yamada, Y | 1 |
| Ahangarpour, A; Badavi, M; Dianat, M; Mard, SA; Ramezani-Aliakbari, F | 1 |
| Bognar, L; Hardi, P; Jancso, G; Nagy, T; Pavlovics, G; Petrovics, L; Takacs, I; Tizedes, G | 1 |
| Abdennebi, HB; Bejaoui, M; Boncompagni, E; Folch-Puy, E; Freitas, I; Garcia-Gil, FA; Pantazi, E; Reiter, RJ; Roselló-Catafau, J; Zaouali, MA | 1 |
| Ben Abdennebi, H; Hadj Ayed Tka, K; Mahfoudh-Boussaid, A; Roselló-Catafau, J; Zaouali, MA | 1 |
| Avcı, B; Çavun, S; Savcı, V; Şentürk, T; Serdar, Z; Yermezler, A | 1 |
| Bejaoui, M; Ben Abdennebi, H; Folch-Puy, E; Palmeira, CM; Pantazi, E; Rolo, AP; Roselló-Catafau, J; Varela, AT; Zaouali, MA | 1 |
| Bejaoui, M; Ben Abdennebi, H; Hadj Ayed, K; Mahfoudh Boussaid, A; Selmi, R; Zaouali, MA | 1 |
| Adam, R; Carbonell, T; Castro, C; Folch, E; Garcia-Gil, A; Lopez, A; Palmeira, CM; Panisello, A; Rolo, A; Roselló-Catafau, J; Zaouali, MA | 1 |
| Belkahia, C; Ben Ali, R; Ben Saîd, D; Elkadri, N; Gaies, E; Klouz, A; Kourda, N; Lakhal, M | 1 |
| Da Silveira, M; Yoshida, WB | 1 |
| Ben Abdennebi, H; Mahfoudh-Boussaid, A; Padrissa-Altés, S; Roselló-Catafau, J; Zaouali, MA | 1 |
| Ben Abdennebi, H; Ghoul-Mazgar, S; Hadj-Ayed, K; Hauet, T; Mahfoudh-Boussaid, A; Miled, AH; Rosello-Catafau, J; Saidane-Mosbahi, D; Zaouali, MA | 1 |
| Atik, U; Aytacoğlu, B; Bilgin, R; Coskun, B; Dikmengil, M; Ercan, B; Gul, A; Sucu, N; Tamer, L; Unlu, A | 1 |
| Kurt, T; Oğuzhanoğlu, A; Ortaç, R; Turman, B | 1 |
| Barriere, M; Baumert, H; Carretier, M; Dutheil, D; Faure, JP; Favreau, F; Goujon, JM; Han, Z; Hauet, T; Mauco, G; Papadopoulos, V; Petit, I; Tallineau, C; Tillement, JP | 1 |
| Chopra, K; Kaur, H; Padi, SS | 1 |
| Doucet, C; Dutheil, D; Eugène, M; Faure, JP; Favreau, F; Goujon, JM; Hauet, T; Mauco, G; Petit, I; Tillement, JP; Vandewalle, A; Zhang, K | 1 |
| Barrière, M; Baumert, H; Dutheil, D; Faure, JP; Favreau, F; Goujon, JM; Hauet, T; Mauco, G; Papadopoulos, V; Petit, I; Tillement, JP; Zhang, K | 1 |
| Dutheil, D; Eugene, M; Faure, JP; Goujon, JM; Hauet, T; Jayle, C; Mauco, G; Petit-Paris, I; Robert, R; Seguin, F; Tillement, JP; Touchard, G; Vandewalle, A; Wahl, A; Zhang, K | 1 |
| Chopra, K; Singh, D | 1 |
| Argaud, L; Couture-Lepetit, E; Gateau-Roesch, O; Gomez, L; Loufouat, J; Ovize, M; Robert, D | 1 |
| Chlubek, D; Ciechanowski, K; Domanski, L; Olszewska, M; Pawlik, A; Safranow, K; Sulikowski, T; Urasinska, E | 1 |
| Batmaz, B; Dernek, S; Erkasap, N; Ikizler, M; Kaygisiz, Z; Kural, T | 1 |
| Barsotti, A; Chierchia, S; De Caterina, R; Di Napoli, P; Felaco, M; Grilli, A; Taccardi, AA | 1 |
| Bartrons, R; Ben Mosbah, I; Boillot, O; Fernández-Monteiro, I; Massip-Salcedo, M; Peralta, C; Roselló-Catafau, J; Xaus, C | 1 |
| Carretier, M; Doucet, C; Eugene, M; Favreau, F; Goujon, JM; Hauet, T; Hebrard, W; Jayle, C; Mauco, G; Tillement, JP; Zhang, K | 1 |
| Bitiren, M; Erel, O; Karatas, OF; Keser, BS; Savas, M; Unal, D; Verit, A; Yeni, E | 1 |
| Bagriyanik, A; Erbil, G; Ergur, BU; Kiray, M; Ozogul, C; Pekcetin, C; Tugyan, K | 1 |
| Cau, J; Favreau, F; Goujon, JM; Hauet, T; Lerman, LO; Tillement, JP | 1 |
| Balaraman, R; Dhote, V | 1 |
| Adler, G; Chlubek, D; Ciechanowicz, A; Ciechanowski, K; Domanski, L; Dziedziejko, V; Pawlik, A; Safranow, K; Sulikowski, T | 1 |
| Calinon, F; Delbarre, B; Delbarre, G | 1 |
| Karayianni, M; Karkabounas, S; Kotoulas, OB; Moschos, CM; Moutesidou, KJ; Tsimoyiannis, EC | 1 |
| Boissel, JP; Bompard, D; Champsaur, G; Lehot, JJ; Vedrinne, C; Vedrinne, JM | 1 |
| Alivanis, P; Dimitriadou, A; Dioudis, C; Grekas, D; Iliadis, S; Papageorgiou, G; Tourkantonis, A; Zilidis, C | 1 |
| Bauza, G; Caritez, JC; Carretier, M; Dore, B; Eugene, M; Goujon, JM; Hauet, T; Le Moyec, L; Mothes, D; Tillement, JP | 1 |
| Caritez, JC; Carretier, M; Eugene, M; Goujon, JM; Hauet, T; le Moyec, L; Mothes, D; Tillement, JP | 1 |
| Cherrah, Y; Elimadi, A; Lamchouri, F; Morin, D; Sapena, R; Settaf, A; Tillement, JP | 1 |
| Baumert, H; Caritez, JC; Carretier, M; Eugene, M; Germonville, T; Hauet, T; Journe, F; Mothes, D; Tillement, JP | 1 |
| Aybek, Z; Calli, N; Düzcan, E; Güner, G; Ozden, A; Saydam, N; Saydam, O | 1 |
| Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Tallineau, C; Tillement, JP | 1 |
| Caritez, JC; Carretier, M; Eugene, M; Germonville, T; Goujon, J; Hauet, T; Mothes, D; Tillement, J | 1 |
| Cherrah, Y; Elimadi, A; Lamchouri, F; Morin, D; Settaf, A; Tillement, JP | 1 |
| Bayramoglu, H; Bilgihan, A; Bostanci, B; Calli, N; Ozden, A; Tetik, C; Yis, O | 1 |
| Baumert, H; Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Lacoste, L; Richer, JP; Tillement, JP | 1 |
| Baumert, H; Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Lacoste, L; Tillement, JP; Vandewalle, A | 1 |
| Amor, IB; Baumert, H; Carretier, M; Eugene, M; Faure, JP; Gibelin, H; Hauet, T; Hebrard, W; Richer, JP; Tillement, JP | 1 |
| Tognoni, G | 1 |
| Hauet, T; Morin, D; Spedding, M; Tillement, J | 1 |
| Mariani, M; Marzilli, M | 1 |
| Kara, CO; Kara, IG; Oçsel, H; Ozden, A | 1 |
| Allibardi, S; Chierchia, S; Costa, S; Monti, LD; Piatti, PM; Pozza, G; Samaja, M; Valsecchi, G | 1 |
| Boehler, A; Dutly, A; Inci, D; Inci, I; Weder, W | 1 |
| Boehler, A; Dutly, A; Inci, I; Rousson, V; Weder, W | 1 |
2 review(s) available for trimetazidine and Reperfusion Injury
| Article | Year |
|---|---|
Pharmacological strategies against cold ischemia reperfusion injury.
Topics: Cold Ischemia; Cold Temperature; Endothelin Receptor Antagonists; Humans; Intercellular Signaling Peptides and Proteins; Melatonin; Organ Preservation; Organ Preservation Solutions; Perfusion; Polyethylene Glycols; Reperfusion Injury; Tissue and Organ Procurement; Trimetazidine | 2010 |
Mitochondria as target for antiischemic drugs.
Topics: Acetanilides; Animals; Antioxidants; Coenzymes; Drug Delivery Systems; Enzyme Inhibitors; Humans; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Piperazines; Potassium Channels; Ranolazine; Reperfusion Injury; Sodium-Calcium Exchanger; Trimetazidine; Ubiquinone; Vasodilator Agents | 2001 |
2 trial(s) available for trimetazidine and Reperfusion Injury
| Article | Year |
|---|---|
Protective effects of trimetazidine on testicular ischemia-reperfusion injury in rats.
Topics: Animals; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Testis; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2007 |
Myocardial protection during coronary artery bypass graft surgery: a randomized, double-blind, placebo-controlled study with trimetazidine.
Topics: Coronary Artery Bypass; Double-Blind Method; Female; Hemodynamics; Humans; Male; Malondialdehyde; Middle Aged; Myocardium; Prospective Studies; Reperfusion Injury; Trimetazidine | 1996 |
60 other study(ies) available for trimetazidine and Reperfusion Injury
| Article | Year |
|---|---|
Naringin and Trimetazidine Improve Baroreflex Sensitivity and Nucleus Tractus Solitarius Electrical Activity in Renal Ischemia-Reperfusion Injury.
Topics: Animals; Baroreflex; Flavanones; Kidney; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Solitary Nucleus; Trimetazidine | 2021 |
Naringin, Trimetazidine and Baroreflex in Renal Ischemia-Reperfusion Injury.
Topics: Baroreflex; Flavanones; Humans; Reperfusion Injury; Trimetazidine | 2021 |
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway.
Topics: Animals; Female; Inflammation; Ischemia; NF-kappa B; Ovary; Rats; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Trimetazidine | 2022 |
The Effect of Trimetazidine on Diathermy-related Thermic Injury of the Rat Liver.
Topics: Animals; Diathermy; Liver; Necrosis; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2022 |
Evaluating the protective role of trimetazidine versus nano-trimetazidine in amelioration of bilateral renal ischemia/reperfusion induced neuro-degeneration: Implications of ERK1/2, JNK and Galectin-3 /NF-κB/TNF-α/HMGB-1 signaling.
Topics: Caspase 3; Galectin 3; HMGB Proteins; Humans; Ischemia; Kidney Diseases; MAP Kinase Signaling System; NF-kappa B; Reperfusion; Reperfusion Injury; Trimetazidine; Tumor Necrosis Factor-alpha | 2023 |
The cystathionine γ-lyase/hydrogen sulfide pathway mediates the trimetazidine-induced protection of H9c2 cells against hypoxia/reoxygenation-induced apoptosis and oxidative stress.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cystathionine gamma-Lyase; Disease Models, Animal; Hydrogen Sulfide; Myocytes, Cardiac; Oxidative Stress; Rats; Reperfusion Injury; Trimetazidine | 2019 |
Protective effects of naringin and trimetazidine on remote effect of acute renal injury on oxidative stress and myocardial injury through Nrf-2 regulation.
Topics: Acute Kidney Injury; Animals; Flavanones; Glutathione Peroxidase; Male; Malondialdehyde; Myocardial Ischemia; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Trimetazidine | 2019 |
Trimetazidine alleviates hypoxia/reoxygenation-induced apoptosis in neonatal mice cardiomyocytes via up-regulating HMGB1 expression to promote autophagy.
Topics: Animals; Animals, Newborn; Apoptosis; Autophagy; Beclin-1; Cell Hypoxia; Cell Survival; Gene Expression Regulation; HMGB1 Protein; Humans; Mice; Microtubule-Associated Proteins; Myocardial Infarction; Myocytes, Cardiac; Reperfusion Injury; Signal Transduction; Trimetazidine | 2021 |
Ex vivo administration of trimetazidine improves post-transplant lung function in pig model.
Topics: Allografts; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Lung Diseases; Lung Transplantation; Postoperative Period; Preoperative Care; Reperfusion Injury; Respiratory Function Tests; Swine; Time Factors; Tissue Donors; Trimetazidine; Vasodilator Agents | 2017 |
The Beneficial Effects of Trimetazidine on Reperfusion-Induced Arrhythmia in Diabetic Rats.
Topics: Animals; Arrhythmias, Cardiac; Diabetes Mellitus, Experimental; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2019 |
The effect of trimetazidine in reducing the ischemia-reperfusion injury in rat epigastric skin flaps.
Topics: Animals; Male; Rats; Rats, Wistar; Reperfusion Injury; Surgical Flaps; Trimetazidine; Vasodilator Agents | 2018 |
The renoprotective effects of naringin and trimetazidine on renal ischemia/reperfusion injury in rats through inhibition of apoptosis and downregulation of micoRNA-10a.
Topics: Animals; Apoptosis; Down-Regulation; Drug Therapy, Combination; Flavanones; Kidney; Male; MicroRNAs; Protective Agents; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2019 |
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Endoplasmic Reticulum Stress; Fatty Liver; Histocytochemistry; Liver Transplantation; Melatonin; Protective Agents; Rats; Rats, Zucker; Reperfusion Injury; Trimetazidine | 2013 |
Effects of trimetazidine on the Akt/eNOS signaling pathway and oxidative stress in an in vivo rat model of renal ischemia-reperfusion.
Topics: Animals; Blotting, Western; Heme Oxygenase-1; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Diseases; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Trimetazidine; Vasodilator Agents | 2014 |
Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury.
Topics: Acetylcysteine; Animals; Apoptosis; Blood Pressure; Caspase 3; Cell Death; Coronary Vessels; Disease Models, Animal; Fatty Acids; Glucose; Glutathione; Inflammation; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit; Trimetazidine | 2014 |
Sirtuin 1 in rat orthotopic liver transplantation: an IGL-1 preservation solution approach.
Topics: Animals; Autophagy; Biomarkers; Cold Ischemia; Graft Survival; Liver; Liver Transplantation; Male; Mitochondria, Liver; Organ Preservation; Organ Preservation Solutions; Oxidative Stress; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Sirtuin 1; Time Factors; Trimetazidine; Up-Regulation | 2015 |
Effectiveness of a single versus repeated administration of trimetazidine in the protection against warm ischemia/reperfusion injury of rat liver.
Topics: Animals; Liver; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine; Warm Ischemia | 2016 |
GSK3β and VDAC Involvement in ER Stress and Apoptosis Modulation during Orthotopic Liver Transplantation.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Glycogen Synthase Kinase 3 beta; Lipid Peroxidation; Liver Function Tests; Liver Transplantation; Male; Mitochondria; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Reperfusion Injury; Trimetazidine; Vasodilator Agents; Voltage-Dependent Anion Channels | 2017 |
Effect of liver hypothermic preservation: exploration and protection.
Topics: Animals; Cell Membrane; Cold Ischemia; Female; Glucose; In Vitro Techniques; Liver; Liver Transplantation; Magnetic Resonance Spectroscopy; Organ Preservation; Organ Preservation Solutions; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine; Tromethamine | 2009 |
Trimetazidine and N-acetylcysteine in attenuating hind-limb ischemia and reperfusion injuries: experimental study in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Creatine Kinase; Disease Models, Animal; Glutathione; Hindlimb; Male; Malondialdehyde; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Time Factors; Trimetazidine | 2009 |
Attenuation of endoplasmic reticulum stress and mitochondrial injury in kidney with ischemic postconditioning application and trimetazidine treatment.
Topics: Animals; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Ischemic Postconditioning; Kidney; Mitochondria; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine | 2012 |
Effects of trimetazidine on tissue damage in kidney after hindlimb ischemia-reperfusion.
Topics: Animals; Glutathione; Hindlimb; Kidney Diseases; Male; Malondialdehyde; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion Injury; Sodium-Potassium-Exchanging ATPase; Superoxide Dismutase; Trimetazidine; Vasodilator Agents | 2002 |
Somatosensory evoked potential and histopathological investigations in ischaemia-induced brain damage: effects of trimetazidine in rats.
Topics: Animals; Brain Ischemia; Cell Death; Chi-Square Distribution; Disease Models, Animal; Evoked Potentials, Somatosensory; Hippocampus; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric; Trimetazidine; Vasodilator Agents | 2003 |
Evidence for a protective role of trimetazidine during cold ischemia: targeting inflammation and nephron mass.
Topics: Animals; Cold Temperature; Drug Delivery Systems; Ischemia; Kidney Function Tests; Kidney Medulla; Nephritis; Nephrons; Reperfusion Injury; Swine; Transplantation, Autologous; Trimetazidine | 2003 |
Attenuation of renal ischemia-reperfusion injury by trimetazidine: evidence of an in vivo antioxidant effect.
Topics: Animals; Antioxidants; Blood Pressure; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drug Administration Schedule; Female; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Lipid Peroxidation; Lipid Peroxides; Male; Rats; Rats, Wistar; Renal Artery Obstruction; Reperfusion Injury; Trimetazidine; Urea | 2003 |
Protective roles of polyethylene glycol and trimetazidine against cold ischemia and reperfusion injuries of pig kidney graft.
Topics: Animals; CD4-Positive T-Lymphocytes; Cold Temperature; Fibrosis; Glomerular Filtration Rate; Graft Survival; Immunohistochemistry; Kidney; Kidney Transplantation; Organ Preservation; Organ Preservation Solutions; Polyethylene Glycols; Potassium; Reperfusion Injury; Solvents; Swine; T-Lymphocytes; Time Factors; Trimetazidine | 2004 |
Evidence for a mitochondrial impact of trimetazidine during cold ischemia and reperfusion.
Topics: Adenosine; Allopurinol; Animals; Biomarkers; Cryopreservation; Disaccharides; Disease Models, Animal; Drug Evaluation, Preclinical; Electrolytes; Glutamates; Glutathione; Histidine; Insulin; Kidney Function Tests; Kidney Transplantation; Mannitol; Mitochondria; Organ Preservation; Organ Preservation Solutions; Raffinose; Receptors, GABA-A; Reperfusion Injury; Swine; Time Factors; Transplantation, Autologous; Trimetazidine | 2004 |
Evidence for protective roles of polyethylene glycol plus high sodium solution and trimetazidine against consequences of renal medulla ischaemia during cold preservation and reperfusion in a pig kidney model.
Topics: Animals; Cold Temperature; Kidney; Kidney Medulla; Organ Preservation; Organ Preservation Solutions; Polyethylene Glycols; Reperfusion Injury; Sodium Chloride; Swine; Time Factors; Trimetazidine | 2004 |
Effect of trimetazidine on renal ischemia/reperfusion injury in rats.
Topics: Animals; Kidney; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Trimetazidine | 2004 |
Trimetazidine inhibits mitochondrial permeability transition pore opening and prevents lethal ischemia-reperfusion injury.
Topics: Animals; Calcium; Calcium Signaling; Ion Channels; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Permeability; Rabbits; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2005 |
Effect of trimetazidine on the nucleotide profile in rat kidney with ischemia-reperfusion injury.
Topics: Adenine Nucleotides; Animals; Antioxidants; Disease Models, Animal; Graft Rejection; Kidney Cortex Necrosis; Kidney Diseases; Kidney Tubules; Male; Organ Preservation; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine | 2006 |
Trimetazidine-induced enhancement of myocardial recovery during reperfusion: a comparative study in diabetic and non-diabetic rat hearts.
Topics: Animals; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Heart; Humans; In Vitro Techniques; Male; Myocardium; Rats; Rats, Sprague-Dawley; Regeneration; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2006 |
Trimetazidine improves post-ischemic recovery by preserving endothelial nitric oxide synthase expression in isolated working rat hearts.
Topics: Animals; Base Sequence; Blotting, Western; Capillary Permeability; DNA Primers; Heart; Male; Myocardium; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Trimetazidine | 2007 |
Addition of adenosine monophosphate-activated protein kinase activators to University of Wisconsin solution: a way of protecting rat steatotic livers.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Enzyme Activators; Fatty Liver; Glutathione; Insulin; Liver; Mitochondria, Liver; Multienzyme Complexes; Nitric Oxide; Nitric Oxide Synthase; Organ Preservation Solutions; Oxidative Stress; Protein Serine-Threonine Kinases; Raffinose; Rats; Rats, Zucker; Reperfusion Injury; Ribonucleotides; Trimetazidine; Vascular Resistance | 2007 |
Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model.
Topics: Animals; Blotting, Western; Creatinine; Gene Expression; Histocompatibility Antigens Class II; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Kidney Cortex; Kidney Function Tests; Kidney Medulla; Male; Nephrectomy; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stathmin; Survival Analysis; Sus scrofa; Time Factors; Treatment Outcome; Trimetazidine; Vascular Cell Adhesion Molecule-1; Vasodilator Agents; Warm Ischemia | 2007 |
The protective effects of trimetazidine on testicular ischemia and reperfusion injury in rats.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Follow-Up Studies; Immunohistochemistry; In Situ Nick-End Labeling; Ischemia; Male; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Spermatozoa; Testis; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2007 |
Trimetazidine reduces early and long-term effects of experimental renal warm ischemia: a dose effect study.
Topics: Animals; Apoptosis; Blotting, Western; Dose-Response Relationship, Drug; Fibrosis; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kidney; Nephrectomy; Renal Circulation; Reperfusion Injury; Swine; Tissue Survival; Trimetazidine; Vasodilator Agents; Vimentin; Warm Ischemia | 2008 |
Anti-oxidant activity mediated neuroprotective potential of trimetazidine on focal cerebral ischaemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Biomarkers; Blood-Brain Barrier; Body Temperature; Brain; Brain Edema; Brain Ischemia; Cerebral Infarction; Male; Neuroprotective Agents; Oxidative Stress; Permeability; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Trimetazidine | 2008 |
Effect of trimetazidine on xanthine oxidoreductase expression in rat kidney with ischemia--reperfusion injury.
Topics: Animals; Kidney; Male; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine; Vasodilator Agents; Xanthine Dehydrogenase | 2008 |
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisates; Gerbillinae; Glutamic Acid; Hydroxybenzoates; Hydroxyl Radical; Ischemia; Male; Reperfusion Injury; Retina; Retinal Vessels; Trimetazidine | 1994 |
Trimetazidine for prevention of hepatic injury induced by ischaemia and reperfusion in rats.
Topics: Animals; Ischemia; Liver; Prospective Studies; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine | 1993 |
Lipid peroxidation after acute renal ischemia and reperfusion in rats: the effect of trimetazidine.
Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Infusions, Intravenous; Lipid Peroxidation; Male; Malondialdehyde; Rats; Renal Artery Obstruction; Reperfusion Injury; Spectrophotometry; Trimetazidine; Vasodilator Agents | 1996 |
Beneficial effect on rat kidney preservation of the antiischemic agent trimetazidine during cold storage and reperfusion: assessment by 31P nuclear magnetic resonance spectroscopy.
Topics: Animals; Cryopreservation; Kidney; Magnetic Resonance Spectroscopy; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine | 1997 |
Trimetazidine prevents renal injury in the isolated perfused pig kidney exposed to prolonged cold ischemia.
Topics: Adenosine; Allopurinol; Animals; Glutathione; Hypertonic Solutions; In Vitro Techniques; Insulin; Ischemia; Kidney; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Renal Circulation; Reperfusion Injury; Swine; Trimetazidine | 1997 |
Trimetazidine counteracts the hepatic injury associated with ischemia-reperfusion by preserving mitochondrial function.
Topics: Adenosine Triphosphate; Animals; Ischemia; Liver; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; NAD; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 1998 |
Lipid peroxidation after cold storage and normothermic reperfusion: the effect of trimetazidine.
Topics: Animals; Cold Temperature; Lipid Peroxidation; Reperfusion; Reperfusion Injury; Swine; Trimetazidine; Vasodilator Agents | 1998 |
Cytoprotective effect of trimetazidine on 75 min warm renal ischemia-reperfusion injury in rats.
Topics: Animals; Glutathione; Ischemia; Kidney; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 1998 |
Efficiency of trimetazidine in renal dysfunction secondary to cold ischemia-reperfusion injury: a proposed addition to University of Wisconsin solution.
Topics: Adenosine; Allopurinol; Animals; Citric Acid; Cold Temperature; Glomerular Filtration Rate; Glutathione; Humans; Insulin; Kidney; Kidney Transplantation; Kidney Tubules; Lactic Acid; Lipid Peroxidation; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Reperfusion Injury; Swine; Trimetazidine | 1998 |
Trimetazidine reverses deleterious effects of ischemia-reperfusion in the isolated perfused pig kidney model.
Topics: Animals; Biomarkers; Cold Temperature; Hypertonic Solutions; Kidney; Kidney Tubules; Magnetic Resonance Spectroscopy; Male; Malondialdehyde; Microscopy, Electron; Models, Biological; Organ Preservation; Organ Preservation Solutions; Organ Size; Perfusion; Reperfusion Injury; Swine; Time Factors; Trimetazidine; Urine | 1998 |
Trimetazidine ameliorates the hepatic injury associated with ischaemia-reperfusion in rats.
Topics: Animals; Liver Diseases; Male; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Trimetazidine | 1999 |
Cytoprotective effect of trimetazidine on 60 minutes of intestinal ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Free Radical Scavengers; Ileum; Intestinal Mucosa; Male; Malondialdehyde; Mesenteric Artery, Superior; Mesenteric Veins; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Trimetazidine | 1999 |
Renoprotective effects of trimetazidine against ischemia-reperfusion injury and cold storage preservation: a preliminary study.
Topics: Adenosine; Allopurinol; Animals; Cold Temperature; Cryoprotective Agents; Glutathione; Graft Survival; Hypertonic Solutions; In Vitro Techniques; Insulin; Kidney; Kidney Transplantation; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Swine; Trimetazidine | 1999 |
Trimetazidine reduces renal dysfunction by limiting the cold ischemia/reperfusion injury in autotransplanted pig kidneys.
Topics: Animals; Cold Temperature; Dimethylamines; Disease Models, Animal; Graft Rejection; Graft Survival; Kidney; Kidney Function Tests; Kidney Transplantation; Male; Methylamines; Reference Values; Reperfusion Injury; Swine; Transplantation, Autologous; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2000 |
Limitation of ischemic damage to the renal medulla by trimetazidine added to Euro-Collins solution: evaluation in an autotransplant model.
Topics: Animals; Creatinine; Hypertonic Solutions; Ischemia; Kidney; Kidney Transplantation; Organ Preservation Solutions; Reperfusion Injury; Swine; Transplantation, Autologous; Trimetazidine; Vasodilator Agents | 2000 |
The EMIP project. European Myocardial Infarction Project.
Topics: Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Reperfusion Injury; Thrombolytic Therapy; Trimetazidine; Vasodilator Agents | 2000 |
About EMIP-FR and reperfusion damage in AMI: a comment to the comment.
Topics: Animals; Humans; Myocardial Infarction; Reperfusion Injury; Trimetazidine; Vasodilator Agents | 2001 |
The effect of trimetazidine on the survival of rat island skin flaps subjected to ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Female; Graft Survival; Rats; Rats, Wistar; Reperfusion Injury; Surgical Flaps; Trimetazidine; Vasodilator Agents | 2001 |
Triglycerides impair postischemic recovery in isolated hearts: roles of endothelin-1 and trimetazidine.
Topics: Animals; Dose-Response Relationship, Drug; Endothelin-1; Glucose; Heart Rate; Hyperglycemia; Hyperinsulinism; In Vitro Techniques; Insulin; Male; Myocardial Ischemia; Myocardial Reperfusion; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Recovery of Function; Reperfusion Injury; Triglycerides; Trimetazidine; Vasodilator Agents; Ventricular Function, Left | 2001 |
Recipient treatment with trimetazidine improves graft function and protects energy status after lung transplantation.
Topics: Animals; Energy Metabolism; Free Radicals; Graft Survival; Lung Transplantation; Male; Rats; Rats, Inbred F344; Reperfusion Injury; Respiratory Distress Syndrome; Trimetazidine; Vasodilator Agents | 2001 |
Trimetazidine protects the energy status after ischemia and reduces reperfusion injury in a rat single lung transplant model.
Topics: Adenosine Triphosphate; Animals; Cold Temperature; Energy Metabolism; Lipid Peroxidation; Lung; Lung Transplantation; Male; Peroxidase; Rats; Rats, Inbred F344; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Trimetazidine; Vasodilator Agents | 2001 |